Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jan Sahai"'
Autor:
Jan Sahai, Shurjeel H. Choudhri, Richard Long, Mark Hawken, Samuel Gathua, George O. Minyiri, Fred Y. Aoki, Daniel S. Sitar, William M. Watkins
Publikováno v:
Clinical Infectious Diseases. 25:104-111
To test the hypothesis that antituberculous drug disposition is altered in patients with AIDS, we studied the steady-state pharmacokinetics of isoniazid (300 mg/d), rifampin (600 mg/d), and pyrazinamide (1,500 mg/d) in 29 adults (14 patients infected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57412a6bb6a233956682bcf561a71142
https://doi.org/10.1086/514513
https://doi.org/10.1086/514513
Publikováno v:
Scopus-Elsevier
Didanosine (ddI) is currently used in the management of patients infected by the human immunodeficiency virus. Rifabutin (RBT) is being extensively used for prophylaxis against Mycobacterium avium complex (MAC) infections. Due to its acid-labile char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ddfeb9d78939373b26bf364e09f3734
https://doi.org/10.1128/aac.41.7.1566
https://doi.org/10.1128/aac.41.7.1566
Publikováno v:
Scopus-Elsevier
The effect of a therapeutic dose of fluconazole on the disposition of zidovudine was evaluated in 12 men infected with human immunodeficiency virus. The study was designed as a randomized, two-period, two-treatment, crossover trial. On two occasions,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d448955ba6d33903f6639617f33cbd10
https://doi.org/10.1093/infdis/169.5.1103
https://doi.org/10.1093/infdis/169.5.1103
Publikováno v:
Antimicrobial Agents and Chemotherapy. 38:894-897
The antacids in two didanosine placebo tablets had no significant effect on the plasma pharmacokinetics of a single oral dose of 300 mg of isoniazid administered to 12 healthy volunteers. These results suggest that isoniazid bioavailability will be u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f50bad8bb529cdee704ef34eb1a25b
https://doi.org/10.1128/aac.38.4.894
https://doi.org/10.1128/aac.38.4.894
Publikováno v:
Antimicrobial Agents and Chemotherapy. 34:550-554
Vancomycin-induced "red man syndrome" (RMS) is mediated in part by histamine release, and its severity is correlated with the area under the plasma histamine concentration-time curve. Ten adult male volunteers participated in a randomized, double-bli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2535a1f575b5134592129cd44dccf069
https://doi.org/10.1128/aac.34.4.550
https://doi.org/10.1128/aac.34.4.550
Publikováno v:
Drug Interactions in Infectious Diseases ISBN: 9781475750317
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead86d8980a86b667811f913d1fd94fa
https://doi.org/10.1385/1-59259-025-x:1
https://doi.org/10.1385/1-59259-025-x:1
Autor:
Francisco Diaz-Mitoma, Jan Sahai, Lionel G. Filion, Frédéric Baribaud, Daniel S. Sitar, Michael J. Orsini, Robert W. Doms, Benjamin J. Doranz, Jeffrey L. Benovic, William Cameron
Publikováno v:
AIDS research and human retroviruses. 17(6)
ALX40-4C is a small peptide inhibitor of the chemokine receptor CXCR4 that can inhibit X4 strains of HIV-1. Prior to the discovery of chemokine receptors as the HIV coreceptors, ALX40-4C was used in phase I/II clinical trials to evaluate its therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470733c81a2b5c4a13f6032853cbeca1
https://pubmed.ncbi.nlm.nih.gov/11350661
https://pubmed.ncbi.nlm.nih.gov/11350661
Autor:
Jan Sahai, K Gallicano
Publikováno v:
British journal of clinical pharmacology. 42(5)
The influence of gender on the single-dose pharmacokinetics of oral ciprofloxacin was investigated in a parallel designed study in 24 healthy, fasted volunteers. Ciprofloxacin (750 mg) was administered as a single tablet to 10 women and 14 men. All s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89e3443f2c21057b75ff9eec5c2b13d
https://pubmed.ncbi.nlm.nih.gov/8951196
https://pubmed.ncbi.nlm.nih.gov/8951196
Publikováno v:
Scopus-Elsevier
Our objective was to determine whether a pharmacokinetic interaction exists between zidovudine and didanosine when they are coadministered. This was designed as a randomized, three-period, three-treatment, six-sequence, crossover study with a 1-week
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302043c93841e61ae6a65ee959c922cf
https://pubmed.ncbi.nlm.nih.gov/7648285
https://pubmed.ncbi.nlm.nih.gov/7648285
Autor:
Jan Sahai
Publikováno v:
Annals of internal medicine. 123(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad183a81de2245700d17a7abc3ded1de
https://pubmed.ncbi.nlm.nih.gov/7625638
https://pubmed.ncbi.nlm.nih.gov/7625638