Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jan Roska"'
Autor:
Zuzana Cierna, Vera Miskovska, Jan Roska, Dana Jurkovicova, Lucia Borszekova Pulzova, Zuzana Sestakova, Lenka Hurbanova, Katarina Machalekova, Michal Chovanec, Katarina Rejlekova, Daniela Svetlovska, Katarina Kalavska, Karol Kajo, Pavel Babal, Jozef Mardiak, Thomas A. Ward, Michal Mego, Miroslav Chovanec
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Germ cell tumours (GCTs) represent a highly curable malignity as they respond well to cisplatin (CDDP)-based chemotherapy. Nevertheless, a small proportion of GCT patients relapse or do not respond to therapy. As this might be cau
Externí odkaz:
https://doaj.org/article/a1198c34116345488384869795332127
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7736 (2020)
Artificial light at night can have negative effects on human wellbeing and health. It can disrupt circadian rhythms, interfere with sleep, and participate in the progress of civilisation diseases. The aim of the present study was to explore if dim ar
Externí odkaz:
https://doaj.org/article/9112f2d251d64abbb97659044d597a07
Autor:
Patrik Palacka, Andrea Holíčková, Jan Roška, Peter Makovický, Miroslava Vallová, Csaba Biró, Eveline Órásová, Jana Obertová, Jozef Mardiak, Thomas A. Ward, Karol Kajo, Miroslav Chovanec
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Cisplatin (CDDP) remains a key agent in the treatment of muscle-infiltrating bladder carcinoma (MIBC). However, a proportion of MIBC patients do not respond to chemotherapy, which may be caused by the increased repair of CDDP-indu
Externí odkaz:
https://doaj.org/article/761780bca58d45ffaf4f2ed1c5328ebb
Autor:
Mangesh Bhide, Eduard Goffa, Lukáš Plank, Dana Jurkovicova, Božena Smolková, Ľudovít Kulcsár, Pavol Slavik, Michal Mego, Katarína Lešková, Michal Kalman, Peter Bujdak, Lucia Pulzova, Ján Kliment, Jan Roska, Miroslav Chovanec
Publikováno v:
Cancers
Cancers, Vol 13, Iss 5573, p 5573 (2021)
Volume 13
Issue 21
Cancers, Vol 13, Iss 5573, p 5573 (2021)
Volume 13
Issue 21
Simple Summary For clinical stage I (CS I) seminoma patients, management through the risk-adapted strategy with adjuvant carboplatin-based chemotherapy in the presence of risk factors and surveillance in the absence of these factors is the preferred
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7736, p 7736 (2020)
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7736, p 7736 (2020)
Artificial light at night can have negative effects on human wellbeing and health. It can disrupt circadian rhythms, interfere with sleep, and participate in the progress of civilisation diseases. The aim of the present study was to explore if dim ar
Autor:
Danica Ivovič, Zuzana Šestáková, Jan Roška, Katarína Kálavská, Lenka Hurbanová, Andrea Holíčková, Božena Smolková, Pavlína Kabelíková, Věra Novotná, Michal Chovanec, Patrik Palacka, Michal Mego, Dana Jurkovičová, Miroslav Chovanec
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundGerm cell tumors (GCTs) represent the most frequent solid malignancy in young men. This malignancy is highly curable by cisplatin (CDDP)-based chemotherapy. However, there is a proportion of patients having a poor prognosis due to refractor
Externí odkaz:
https://doaj.org/article/7ca865402d77409db04d838cc3902f32
Autor:
Jozef Mardiak, Katarina Machalekova, Zuzana Sestakova, Thomas Ward, Zuzana Cierna, Lucia Pulzova, Dana Jurkovicova, Karol Kajo, Katarina Rejlekova, Miroslav Chovanec, Daniela Svetlovska, Pavel Babal, Jan Roska, Katarina Kalavska, Michal Chovanec, Vera Miskovska, Michal Mego, Lenka Hurbanova
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
Background Germ cell tumours (GCTs) represent a highly curable malignity as they respond well to cisplatin (CDDP)-based chemotherapy. Nevertheless, a small proportion of GCT patients relapse or do not respond to therapy. As this might be caused by an
Autor:
Zuzana Sestakova, Zuzana Sycova-Mila, Miroslav Chovanec, Bozena Smolkova, Lenka Hurbanova, Daniela Svetlovska, Katarina Rejlekova, Jozef Mardiak, Dana Jurkovicova, Jan Roska, Jana Obertova, Michal Chovanec, Patrik Palacka, Andrea Holickova, Vera Miskovska, Michal Mego, Eduard Goffa, Katarina Kalavska
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. :503200
Germ cell tumour (GCT) patients who fail to respond to chemotherapy or who relapse have a poor prognosis. Timely and accurately stratifying such patients could optimise their therapy. We identified endogenous DNA damage levels as a prognostic marker
Autor:
Jan Roška, João Lobo, Danica Ivovič, Lenka Wachsmannová, Thomas Mueller, Rui Henrique, Carmen Jerónimo, Miroslav Chovanec, Dana Jurkovičová
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2495 (2023)
Testicular germ cell tumours (TGCTs) are the most common solid malignancy among young men, and their incidence is still increasing. Despite good curability with cisplatin (CDDP)-based chemotherapy, about 10% of TGCTs are non-responsive and show a che
Externí odkaz:
https://doaj.org/article/dea6b825444f4ff9bba97c80dcbf6eab
Autor:
Andrea Holíčková, Jan Roška, Eveline Órásová, Vladimíra Bruderová, Patrik Palacka, Dana Jurkovičová, Miroslav Chovanec
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12488 (2022)
Cisplatin (CDDP)-based chemotherapy is the standard of care in patients with muscle-invasive bladder cancer. However, in a large number of cases, the disease becomes resistant or does not respond to CDDP, and thus progresses and disseminates. In such
Externí odkaz:
https://doaj.org/article/29bc1fdb3f4a482890ff8a984f6e732f