Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jan Roger Olsen"'
Autor:
Waqas Azeem, Jan Roger Olsen, Margrete Reime Hellem, Yaping Hua, Kristo Marvyin, Xisong Ke, Anne Margrete Øyan, Karl-Henning Kalland
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 473 (2022)
GATA2 has been shown to be an important transcription factor together with androgen receptor (AR) in prostate cancer cells. Less is known about GATA2 in benign prostate epithelial cells. We have investigated if GATA2 exogenous expression in prostate
Externí odkaz:
https://doaj.org/article/8df1866ef7084d4086ab35156a649e34
Autor:
Waqas Azeem, Margrete Reime Hellem, Jan Roger Olsen, Yaping Hua, Kristo Marvyin, Yi Qu, Biaoyang Lin, Xisong Ke, Anne Margrete Øyan, Karl-Henning Kalland
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0177861 (2017)
The androgen receptor (AR) transcription factor plays a key role in the development and progression of prostate cancer, as is evident from the efficacy of androgen-deprivation therapy, AR is also the most frequently mutated gene, in castration resist
Externí odkaz:
https://doaj.org/article/3a63f1dfd7674a55960d2cc38fba377f
Autor:
Jan Roger Olsen, Anne Margrete Oyan, Kari Rostad, Margrete R Hellem, Jie Liu, Lisha Li, David R Micklem, Hallvard Haugen, James B Lorens, Varda Rotter, Xi-Song Ke, Biaoyang Lin, Karl-Henning Kalland
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62547 (2013)
The transcription factor p63 is central for epithelial homeostasis and development. In our model of epithelial to mesenchymal transition (EMT) in human prostate cells, p63 was one of the most down-regulated transcription factors during EMT. We theref
Externí odkaz:
https://doaj.org/article/d7fd1bb4aff245c3a9fcd44b2011fe53
Autor:
Liv Cecilie Vestrheim Thomsen, Alfred Honoré, Lars Anders Rokne Reisæter, Bjarte Almås, Astrid Børretzen, Svein Inge Helle, Kristina Førde, Einar Klæboe Kristoffersen, Silje Helland Kaada, Guro Kristin Melve, Torjan Magne Haslerud, Martin Biermann, Iris Bigalke, Gunnar Kvalheim, Waqas Azeem, Jan Roger Olsen, Benjamin Gabriel, Stian Knappskog, Ole Johan Halvorsen, Lars Andreas Akslen, Duke Bahn, Klaus Pantel, Sabine Riethdorf, Haakon Ragde, Bjørn Tore Gjertsen, Anne Margrete Øyan, Karl-Henning Kalland, Christian Beisland
Publikováno v:
Cancer Immunology and Immunotherapy
Metastatic castration-resistant prostate cancer (mCRPC) is an immunologically cold disease with dismal outcomes. Cryoablation destroys cancer tissue, releases tumor-associated antigens and creates a pro-inflammatory microenvironment, while dendritic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa514300d3dcf5153ca8cadad17daf3a
https://hdl.handle.net/11250/3069109
https://hdl.handle.net/11250/3069109
Autor:
Wei-Dong Zhang, Xisong Ke, Jan Roger Olsen, Yun-Heng Shen, Anne Margrete Øyan, Karl-Henning Kalland, Yaping Hua, Waqas Azeem, Shoude Zhang
Publikováno v:
Pharmacology Research & Perspectives
Prostate cancer (PCa) often recurs as incurable castration‐resistant prostate cancer (CRPC) after the failure of androgen deprivation therapy. CRPC development relies on androgen receptor (AR) signaling. The IL6/STAT3 pathway is also a key driver o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412adf2965bc8ab8a9d8b2ef294f6357
http://europepmc.org/articles/PMC6218398
http://europepmc.org/articles/PMC6218398
Autor:
Jan Roger Olsen, Xisong Ke, Yaping Hua, Yi Qu, Karl-Henning Kalland, Waqas Azeem, Anne Margrete Øyan
Publikováno v:
Biomarkers of the Tumor Microenvironment ISBN: 9783319391458
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbd18a748aa6fe89235ee683955c0315
https://doi.org/10.1007/978-3-319-39147-2_23
https://doi.org/10.1007/978-3-319-39147-2_23
Autor:
Paul S. Hoffman, Xisong Ke, Anne Margrete Øyan, Karl-Henning Kalland, Jan Roger Olsen, Yi Qu, Weidong Zhang, Phil F. Cheng, Xing Yuan, Karl A. Brokstad, Mitchell P. Levesque
Publikováno v:
Nature chemical biology. 14(1)
Wnt (wingless)/β-catenin signaling is critical for tumor progression and is frequently activated in colorectal cancer as a result of the mutation of adenomatous polyposis coli (APC); however, therapeutic agents targeting this pathway for clinical us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69d8a151c514c27baa5631c55cc67e09
https://pubmed.ncbi.nlm.nih.gov/29083417
https://pubmed.ncbi.nlm.nih.gov/29083417
Autor:
Jan Roger Olsen, Margrete R. Hellem, Xisong Ke, Karl-Henning Kalland, Waqas Azeem, Yi Qu, Biaoyang Lin, Kristo Marvyin, Lisha Li, Anne Margrete Øyan, Yaping Hua
Publikováno v:
BMC Cancer
Background Expression of the androgen receptor (AR) is associated with androgen-dependent proliferation arrest and terminal differentiation of normal prostate epithelial cells. Additionally, activation of the AR is required for survival of benign lum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46796a994f1b5c37135ff595221f5827
https://doi.org/10.1186/s12885-016-2453-4
https://doi.org/10.1186/s12885-016-2453-4
Autor:
Anders Molven, Emmet McCormack, Xisong Ke, Lars A. Akslen, Varda Rotter, Randi Hovland, Frits Thorsen, Jan Roger Olsen, Karl-Henning Kalland, Run-Hui Liu, Anne Margrete Øyan, Ira Kogan-Sakin, Wen-Cheng Li, Yi Qu
Publikováno v:
Experimental Cell Research. 317:234-247
Epithelial to mesenchymal transition (EMT) is pivotal in tumor metastasis. Our previous work reported an EMT model based on primary prostate epithelial cells (EP156T) which gave rise to cells with mesenchymal phenotype (EPT1) without malignant transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec705e529cc389ccadc4bd900199671
https://doi.org/10.1016/j.yexcr.2010.10.009
https://doi.org/10.1016/j.yexcr.2010.10.009
Autor:
Jan Roger Olsen, Ole J. Halvorsen, Torjan Haslerud, Duke Bahn, Klaus Pantel, Anne Margrete Øyan, Jarle Rørvik, Martin Biermann, Liv Cecilie Vestrheim Thomsen, Lars A. R. Reisæter, Christian Beisland, Einar K. Kristoffersen, Haakon Ragde, Bjarte Almås, Gunnar Kvalheim, Svein Inge Helle, Karl-Henning Kalland, Alfred Honoré, Jannicke Frugård, Lars A. Akslen, Guro Kristin Melve, Waqas Azeem, Bjørn Tore Gjertsen, Sabine Riethdorf
Publikováno v:
Cancer Research. 78:CT066-CT066
Interim analysis data are presented for 13 patients with metastatic castration resistant prostate cancer treated with dendritic cell based cryoimmunotherapy (CryoIT) and at least three months follow-up (FU). In CryoIT autologous immature dendritic ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75aa4a5a15961302b27ad86d76c7dca2
https://doi.org/10.1158/1538-7445.am2018-ct066
https://doi.org/10.1158/1538-7445.am2018-ct066