Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jan Rehkämper"'
Autor:
Konrad Steinestel, Marcel Trautmann, Esther‐Pia Jansen, Uta Dirksen, Jan Rehkämper, Jan‐Henrik Mikesch, Julia S. Gerke, Martin F. Orth, Giuseppina Sannino, Maria‐Francisca Arteaga, Claudia Rossig, Eva Wardelmann, Thomas G. P. Grünewald, Wolfgang Hartmann
Publikováno v:
Molecular Oncology, Vol 14, Iss 2, Pp 248-260 (2020)
Oncogenesis of Ewing sarcoma (EwS), the second most common malignant bone tumor of childhood and adolescence, is dependent on the expression of chimeric EWSR1‐ETS fusion oncogenes, most often EWSR1‐FLI1 (E/F). E/F expression leads to dysregulatio
Externí odkaz:
https://doaj.org/article/3db38cc851124a8999775124ae77ddbe
Autor:
Arik Bernard Schulze, Lars Henning Schmidt, Birthe Heitkötter, Sebastian Huss, Michael Mohr, Alessandro Marra, Ludger Hillejan, Dennis Görlich, Peter J. Barth, Jan Rehkämper, Georg Evers
Publikováno v:
Thoracic Cancer, Vol 11, Iss 1, Pp 120-129 (2020)
Abstract Background Epithelial‐to‐mesenchymal transition (EMT) is a crucial step in lung cancer pathogenesis. Among others, cancer‐associated fibroblasts (CAFs) are reported to regulate this process. Objectives To investigate the prognostic and
Externí odkaz:
https://doaj.org/article/00133ab18bdc4c0d9e10576bb102f670
Autor:
Katharina Stock, Rebekka Borrink, Jan-Henrik Mikesch, Anna Hansmeier, Jan Rehkämper, Marcel Trautmann, Eva Wardelmann, Wolfgang Hartmann, Jan Sperveslage, Konrad Steinestel
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-15 (2019)
Abstract Background The nucleation-promoting factor cortactin is expressed and promotes tumor progression and metastasis in various cancers. However, little is known about the biological role of cortactin in the progression of pancreatic ductal adeno
Externí odkaz:
https://doaj.org/article/b8529c2a6daf4252982af6a08f97ac17
Autor:
Nicole Bäumer, Jan Rehkämper, Neele Appel, Lisa Terheyden, Wolfgang Hartmann, Eva Wardelmann, Frank Buchholz, Carsten Müller-Tidow, Wolfgang E Berdel, Sebastian Bäumer
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200163 (2018)
Precision cancer therapy requires on the one hand detailed knowledge about a tumor's driver oncogenes and on the other hand an effective targeted therapy that specifically inhibits these oncogenes. While the determination of genomic landscape of a tu
Externí odkaz:
https://doaj.org/article/5efa86aae4484dd99b3e519038989d02
Autor:
Alessandro Marra, Lars Henning Schmidt, Arik Bernard Schulze, Michael Mohr, Georg Evers, Jan Rehkämper, Dennis Görlich, Ludger Hillejan, Birthe Heitkötter
Publikováno v:
J Thorac Dis
BACKGROUND: T cell infiltration in non-small cell lung cancer (NSCLC) is essential for the immunological response to malignant tissue, especially in the era of immune-checkpoint inhibition. To investigate the prognostic impact of CD4(+) T helper cell
Autor:
Jessica Becker, Jan Rehkämper, Heidrun Gevensleben, Eva Wardelmann, Inga Grünewald, Wolfgang Hartmann, Marcel Trautmann, Sebastian Huss
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Desmoid-type fibromatosis (DTF, aggressive fibromatosis) is a non-metastasizing mesenchymal neoplasm of deep soft tissue with a tendency towards local recurrence. Genetic alterations affecting canonical Wnt/β-catenin signaling are reported in the ma
Autor:
Felix Noah Freppon, Anne Helfen, Moritz Wildgruber, Andre Beuker, Michel Eisenblätter, Rebecca Buchholz, Alexander Kraupner, Mirjam Gerwing, Carsten Höltke, Cornelius Faber, Franziska Albers, Max Masthoff, Jan Rehkämper, Lydia Wachsmuth, Uwe Hansen, Uwe Karst, Torsten Vielhaber, Walter Heindel
Publikováno v:
Nano Letters. 19:7908-7917
Iron oxide nanoparticles (ION) are highly sensitive probes for magnetic resonance imaging (MRI) that have previously been used for in vivo cell tracking and have enabled implementation of several diagnostic tools to detect and monitor disease. Howeve
Autor:
Sebastian Huss, Georg Gosheger, Wolfgang Hartmann, Jan Rehkämper, Eva Wardelmann, Elena Hekeler, Birte Jeiler, Daniel Baumhoer, Arne Streitbürger, Sandra Elges, Konrad Steinestel, Jendrik Hardes, Marcel Trautmann, Jan Sperveslage
Publikováno v:
Oncotarget
The diagnosis of giant cell-rich lesions of bone can be challenging if radiological findings are ambiguous and tissue of the biologically deciding component is underrepresented in biopsy specimens. The frequent association of giant cell tumor of bone
Autor:
Claudia Rudack, Eva Wardelmann, Khaled Elsayad, Hans Theodor Eich, Uwe Haverkamp, Stephan Maring, Markus Stenner, Jan Rehkämper
Publikováno v:
Oncology Research and Treatment. 41:736-743
Background: Cisplatin-based chemotherapy (CTX) is commonly used concurrently with radiotherapy for head and neck cancer. The value of CTX regimens other than cisplatin for locally advanced squamous cell carcinoma of head and neck (LASCCHN) has not be
Autor:
Rebekka Wiesch, Konrad Steinestel, Jan Sperveslage, Marcel Trautmann, Wolfgang Hartmann, Sebastian Huss, Jan-Henrik Mikesch, Nora Beller, Jan Rehkämper, Birthe Heitkötter, Katharina Stock, Eva Wardelmann, Anna Hansmeier
Publikováno v:
BioMed Research International, Vol 2017 (2017)
BioMed Research International
BioMed Research International
Aims. Expression of PSMA (prostate-specific membrane antigen) has been demonstrated in various cancers, including pancreatic ductal adenocarcinoma (PDAC). However, PSMA expression in PDAC-associated neovasculature has so far not been systematically a