Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Jan R. Mead"'
Publikováno v:
Microorganisms, Vol 10, Iss 9, p 1822 (2022)
In a previous study, we observed an increase in the severity of cryptosporidial infection corresponding to decreased levels of short-chain fatty acids (SCFAs). Therefore, we decided to examine the effect of SCFAs on Cryptosporidium growth in human il
Externí odkaz:
https://doaj.org/article/353f06fbf18b4038ae05266d450a3fae
Publikováno v:
Microorganisms, Vol 8, Iss 6, p 879 (2020)
Cryptosporidium spp. are opportunistic protozoan parasites that infect epithelial cells of the small intestine, causing diarrheal illness in humans. Differences in severity may be due to the immunological status of the host, malnutrition or prior exp
Externí odkaz:
https://doaj.org/article/3e5c7c7b8f404945b5e9769d8af19a21
Autor:
Jan R. Mead
Publikováno v:
Frontiers in Parasitology. 2
Cryptosporidium spp. are opportunistic protozoan parasites that infect epithelial cells of the small intestine and cause diarrheal illness in both immunocompetent and immunodeficient individuals. These infections may be more severe in immunocompromis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b511dd58e573dcc09bc914cf40e8d1fc
https://doi.org/10.3389/fpara.2023.1113950
https://doi.org/10.3389/fpara.2023.1113950
Autor:
Seungheon Lee, Melissa S. Love, Ramkumar Modukuri, Arnab K. Chatterjee, Lauren Huerta, Ann P. Lawson, Case W. McNamara, Jan R. Mead, Lizbeth Hedstrom, Gregory D. Cuny
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 90:129328
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dcf446f9831cd2db958c5601a963e15
https://doi.org/10.1016/j.bmcl.2023.129328
https://doi.org/10.1016/j.bmcl.2023.129328
Publikováno v:
Microbes and Infection. 20:369-375
Cryptosporidium spp. are opportunistic protozoan parasites that infect epithelial cells in the intestinal tract and cause a flu-like diarrheal illness. Innate immunity is key to limiting the expansion of parasitic stages early in infection. One mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e754b53bead8661154312efc57df9f
https://doi.org/10.1016/j.micinf.2018.04.006
https://doi.org/10.1016/j.micinf.2018.04.006
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2052
Cryptosporidiosis threatens life of young children in developing countries and newborn calves around the world. No vaccine or therapy can prevent or cure this diarrhea-inducing enteric disease caused by Cryptosporidium spp. protozoan parasites. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab61609422cabc8b675f0da18abfba04
https://pubmed.ncbi.nlm.nih.gov/31452166
https://pubmed.ncbi.nlm.nih.gov/31452166
Publikováno v:
Methods in Molecular Biology ISBN: 9781493997473
Cryptosporidiosis threatens life of young children in developing countries and newborn calves around the world. No vaccine or therapy can prevent or cure this diarrhea-inducing enteric disease caused by Cryptosporidium spp. protozoan parasites. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::312858ceccdc3e80a4d288be0c15cb84
https://doi.org/10.1007/978-1-4939-9748-0_14
https://doi.org/10.1007/978-1-4939-9748-0_14
Publikováno v:
The Journal of infectious diseases. 217(7)
BACKGROUND: Cryptosporidiosis affects all human populations, but can be much more severe or life-threatening in children and individuals with weak or weakened immune systems. However, current options to treat cryptosporidiosis are limited. METHODS: A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f8af8a2b98a9f0ad00c983c0c5e9a7
https://pubmed.ncbi.nlm.nih.gov/29300993
https://pubmed.ncbi.nlm.nih.gov/29300993
Publikováno v:
Journal of Eukaryotic Microbiology. 62:44-50
IL-18 is known to play a key role limiting Cryptosporidium parvum infection. In this study, we show that IL-18 depletion in SCID mice significantly exacerbates C. parvum infection, whereas, treatment with recombinant IL-18 (rIL-18), significantly dec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169a89eb3fda10cb485d8eb0b5ba84e0
https://doi.org/10.1111/jeu.12164
https://doi.org/10.1111/jeu.12164
Autor:
Jan R. Mead
Publikováno v:
Human Vaccines & Immunotherapeutics
Cryptosporidium spp is a ubiquitous parasite that has long been recognized as a frequent cause of protozoal diarrhea in humans. While infections in immunocompetent hosts are usually self-limiting, immunocompromised individuals can develop severe, chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b3b3e6fd688537b0d87c1d8a59dbac
https://doi.org/10.4161/hv.28485
https://doi.org/10.4161/hv.28485