Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jan Pullen"'
Autor:
Lon R. Cardon, Tessa A. M. Rademaker, Yurii S. Aulchenko, Peter Heutink, Lodewijk A. Sandkuijl, Ben A. Oostra, Jan Pullen, Ian Mackay, Aida M. Bertoli-Avella, Norbert Vaessen, Cornelia M. van Duijn
Publikováno v:
European Journal of Human Genetics, 12, 527-534. Nature Publishing Group
The design and feasibility of genetic studies of complex diseases are critically dependent on the extent and distribution of linkage disequilibrium (LD) across the genome and between different populations. We have examined genomewide and region-speci
Autor:
Peter Heutink, Ben A. Oostra, Lodewijk A. Sandkuijl, Norbert Vaessen, Mark Edwards, P.J.L.M. Snijders, Jeanine J. Houwing-Duistermaat, Jan Pullen, Yurii S. Aulchenko, Simon T. Bennett, Cornelia M. van Duijn, Albert Hofman
Publikováno v:
Diabetes, 52(12), 3001-3004. American Diabetes Association Inc.
Multiple genes, interacting with the environment, contribute to the susceptibility to type 2 diabetes. We performed a genome-wide search to localize type 2 diabetes susceptibility genes in a recently genetically isolated population in the Netherlands
Autor:
Jan Pullen, Ruth M. Hadfield, Daniel E. Weeks, Simon T. Bennett, Joseph W. Kemnitz, Stephen Kennedy, Sarah Wolfensohn, Kay F. Davies
Publikováno v:
American journal of primatology. 54(4)
Linkage analysis can be problematic in humans because of the lack of large, multigenerational pedigrees and the difficulties in obtaining phenotypic data on all family members. In contrast, large, captive colonies of rhesus macaque are a potentially