Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jan Provaznik"'
Autor:
Maximilian Seidel, Natalie Romanov, Agnieszka Obarska-Kosinska, Anja Becker, Nayara Trevisan Doimo de Azevedo, Jan Provaznik, Sankarshana R. Nagaraja, Jonathan J. M. Landry, Vladimir Benes, Martin Beck
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Various cellular quality control mechanisms support proteostasis. While, ribosome-associated chaperones prevent the misfolding of nascent chains during translation, importins were shown to prevent the aggregation of specific cargoes in a pos
Externí odkaz:
https://doaj.org/article/55dc045fc9ed44c1b929ae9a590b88c8
Autor:
Benoît Arragain, Quentin Durieux Trouilleton, Florence Baudin, Jan Provaznik, Nayara Azevedo, Stephen Cusack, Guy Schoehn, Hélène Malet
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
La Crosse is a human life threatening virus belonging to the Bunyavirales order. The structure of its polymerase solved in seven key active states by cryo-electron microscopy reveals the molecular mechanisms of viral RNA replication and transcription
Externí odkaz:
https://doaj.org/article/baf0b7f62a9c4fc8a3d6e52a3256d0b6
Autor:
Volker Adams, T. Scott Bowen, Sarah Werner, Peggy Barthel, Christina Amberger, Anne Konzer, Johannes Graumann, Peter Sehr, Joe Lewis, Jan Provaznik, Vladimir Benes, Petra Büttner, Alexander Gasch, Norman Mangner, Christian C. Witt, Dittmar Labeit, Axel Linke, Siegfried Labeit
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 5, Pp 1102-1115 (2019)
Abstract Background Chronic heart failure (CHF) leads to diaphragm myopathy that significantly impairs quality of life and worsens prognosis. In this study, we aimed to assess the efficacy of a recently discovered small‐molecule inhibitor of MuRF1
Externí odkaz:
https://doaj.org/article/fddeac7b5c624a939be3a2e90aa2c0f4
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-20 (2019)
Abstract Background Cancer-initiating cell (CIC) exosomes (CIC-TEX) are suggested reprogramming Non-CIC. Mode of message transfer and engagement of CIC-markers being disputed, we elaborated the impact of CD44v6 and Tspan8 on the response of Non-CIC.
Externí odkaz:
https://doaj.org/article/57476ca358104cc89e029ab94533784b
CRISPR/Cas9 Genome Editing Introduction and Optimization in the Non-model Insect Pyrrhocoris apterus
Autor:
Joanna Kotwica-Rolinska, Lenka Chodakova, Daniela Chvalova, Lucie Kristofova, Iva Fenclova, Jan Provaznik, Maly Bertolutti, Bulah Chia-Hsiang Wu, David Dolezel
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
The CRISPR/Cas9 technique is widely used in experimentation with human cell lines as well as with other model systems, such as mice Mus musculus, zebrafish Danio reiro, and the fruit fly Drosophila melanogaster. However, publications describing the u
Externí odkaz:
https://doaj.org/article/a8da3ed0e9d24f91ad451017fcdc4b2d
Publikováno v:
Cells, Vol 9, Iss 2, p 319 (2020)
Tumor cell-derived extracellular vesicles (TEX) expressing tetraspanin Tspan8-alpha4/beta1 support angiogenesis. Tspan8-alpha6/beta4 facilitates lung premetastatic niche establishment. TEX-promoted target reprogramming is still being disputed, we exp
Externí odkaz:
https://doaj.org/article/92c9ddd219b04650840ec9bc3ce30560
Autor:
Margot Zöller, Kun Zhao, Natalia Kutlu, Nathalie Bauer, Jan Provaznik, Thilo Hackert, Martina Schnölzer
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The treatment of autoimmune diseases still poses a major challenge, frequently relying on non-specific immunosuppressive drugs. Current efforts aim at reestablishing self tolerance using immune cells with suppressive activity like the regulatory T ce
Externí odkaz:
https://doaj.org/article/a2627228eb1745b7a9171e7de8538fec
Autor:
Cheryl S.Y. Yeap, Nhung H.A. Nguyen, Roman Spanek, Chin Chin Too, Vladimir Benes, Jan Provaznik, Miroslav Cernik, Alena Sevcu
Publikováno v:
Journal of hazardous materials. 439
Nanoscale zero-valent iron (nZVI) has increasingly been applied to remediate aquifers polluted by organochlorines or heavy metals. As a result, bacteria in the vicinity of remediate action can be stressed by surplus iron released from nZVI. However,
Autor:
Valentina Strohmeier, Geoffroy Andrieux, Susanne Unger, Anna Pascual-Reguant, Adam Klocperk, Maximilian Seidl, Otavio Cabral Marques, Marleen Eckert, Katja Gräwe, Michelle Shabani, Caroline von Spee-Mayer, David Friedmann, Ina Harder, Sylvia Gutenberger, Baerbel Keller, Michele Proietti, Alla Bulashevska, Bodo Grimbacher, Jan Provaznik, Vladimir Benes, Sigune Goldacker, Christoph Schell, Anja E. Hauser, Melanie Boerries, Peter Hasselblatt, Klaus Warnatz
Publikováno v:
Journal of clinical immunology.
Purpose About 15% of patients with common variable immunodeficiency (CVID) develop a small intestinal enteropathy, which resembles celiac disease with regard to histopathology but evolves from a distinct, poorly defined pathogenesis that has been lin
Autor:
Jan Provaznik, Daria Rapoport, Vladimir Benes, Dinko Pavlinic, Jan Kopecky, Marketa Sagova-Mareckova, Stanislava Králová, Ivo Sedláček
Publikováno v:
International Journal of Systematic and Evolutionary Microbiology. 70:5106-5114
A novel actinobacterial strain, designated 15TR583T, was isolated from a waterlogged acidic soil collected near the town of Trebon, Czech Republic, and was subjected to a polyphasic taxonomic characterization. Phylogenetic analysis based on 16S rRNA