Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jan Proška"'
Publikováno v:
Acta Polytechnica, Vol 54, Iss 5, Pp 320-324 (2014)
In this study, the structuring of micro- and nanocrystalline diamond thin films is demonstrated. The structuring of the diamond films is performed using the technique of microsphere lithography followed by reactive ion etching. Specifically, this p
Externí odkaz:
https://doaj.org/article/23bf1a547cd3434eb3bd0d1538a432c3
Publikováno v:
Nanomaterials, Vol 9, Iss 10, p 1426 (2019)
Surface-enhanced Raman scattering (SERS) sensors are constructed from metallic plasmonic nanostructures providing high sensitivity and spectral reproducibility. In many cases, irradiation of the SERS substrate by the laser beam leads to an increase o
Externí odkaz:
https://doaj.org/article/7752399679a5481497519020bf40a9c9
Publikováno v:
ResearcherID
New derivatives of anpirtoline and deazaanpirtoline modified in the side chain have been synthesized. The series includes compounds 3 with side-chains containing piperidine or pyrrolidine rings, compounds 4 containing 8-azabicyclo[3.2.1]octane moiety
Publikováno v:
Scopus-Elsevier
Molecular modification of anpirtoline (2a) is described. Several methods of preparation of 4-[(3-chlorophenyl)sulfanyl]-1-methylpiperidine (3a) and its demethylation led to the deazaanpirtoline (3c). Nucleophilic substitution of piperidine-4-thiole w
Publikováno v:
Archiv der Pharmazie. 332:13-18
receptorligandsSummaryIntroductionWorldwide attention is focused on the development ofcentrally acting analgesics of non-opioid type. The key re-quirement for this type of centrally acting drugs is their modeof action not involving opiate receptors.
Publikováno v:
Collection of Czechoslovak Chemical Communications. 64:1980-1992
Bis-quaternary salts of 3-piperidinopropyl esters of α-truxillic acid were synthesized in order to study their allosteric action on muscarinic acetylcholine receptor. Using radioligand binding studies, it has been demonstrated that most of prepared
Autor:
Jan Proška, Stanislav Tuček
Publikováno v:
Trends in Pharmacological Sciences. 16:205-212
Five subtypes of muscarinic acetylcholine receptors have been identified in mammalian tissues, but the selectivity of ligandsthat are active at these receptors is low. It is possible, however, that selective compounds may be developed by targeting th
Publikováno v:
ChemInform. 30
receptorligandsSummaryIntroductionWorldwide attention is focused on the development ofcentrally acting analgesics of non-opioid type. The key re-quirement for this type of centrally acting drugs is their modeof action not involving opiate receptors.
Publikováno v:
ChemInform. 30
Publikováno v:
ChemInform. 30