Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jan Philip, Höpner"'
Autor:
Thomas, Parigger, Franz Josef, Gassner, Christian, Scherhäufl, Aryunni Abu, Bakar, Jan Philip, Höpner, Alexandra, Hödlmoser, Markus, Steiner, Kemal, Catakovic, Roland, Geisberger, Richard, Greil, Nadja, Zaborsky
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6648, p 6648 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences
Volume 22
Issue 13
The reinvigoration of anti-cancer immunity by immune checkpoint therapies has greatly improved cancer treatment. In chronic lymphocytic leukemia (CLL), patients as well as in the Tcl1 mouse model for CLL, PD1-expressing, exhausted T cells significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1fe1d265b4157f16447d730e57874d00
https://www.mdpi.com/1422-0067/22/13/6648
https://www.mdpi.com/1422-0067/22/13/6648
Autor:
Maria, Schubert, Franz Josef, Gassner, Michael, Huemer, Jan Philip, Höpner, Ekaterina, Akimova, Markus, Steiner, Alexander, Egle, Richard, Greil, Nadja, Zaborsky, Roland, Geisberger
Publikováno v:
Cancers, Vol 13, Iss 2619, p 2619 (2021)
Cancers
Volume 13
Issue 11
Cancers
Volume 13
Issue 11
Simple Summary Cancers, such as chronic lymphocytic leukemia, frequently acquire consecutive somatic mutations in the genome, which contribute to disease progression and treatment resistance. Activation-induced deaminase is an enzyme responsible for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1213148398caf9093f13dd8d7ad03ee6
https://www.mdpi.com/2072-6694/13/11/2619
https://www.mdpi.com/2072-6694/13/11/2619
Autor:
Marc Artinger, Véronique Orian-Rousseau, Lisa Pleyer, Fritz Aberger, Suzana Tesanovic, Elisabeth Bayer, Daniel Neureiter, Andrea Härzschel, Valerie Durand-Onayli, Tanja Rieß, Jan Philip Höpner, Alexandre Chigaev, Georg Auer, Julia Christine Gutjahr, Nadja Zaborsky, Richard Greil, Daniel F. Legler, Julia M. Laufer, Sandra Pennisi, Astrid Salmhofer, Xiaobing Yu, Andrea Ramspacher, Tanja Nicole Hartmann, Theresa Haslauer, Eva Szenes
Publikováno v:
Haematologica, 106 (8), 2102-2113
Haematologica
Haematologica
Adhesive properties of leukemia cells shape the degree of organ infiltration and the extent of leukocytosis. CD44 and the integrin VLA-4, a CD49d/CD29 heterodimer, are important factors of progenitor cell adhesion in bone marrow (BM). Here, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7bde17c88e6e52bc9f73a02d5ff2aa8
https://publikationen.bibliothek.kit.edu/1000127084
https://publikationen.bibliothek.kit.edu/1000127084
Autor:
Roland Geisberger, Nadja Zaborsky, Richard Greil, Daniel Hebenstreit, Maria Schubert, Franz Josef Gassner, Alexander Egle, Daniela Asslaber, Richard Stark, Jan Philip Höpner, Markus Steiner
Publikováno v:
Leukemia
The TCL1 mouse model is widely used to study pathophysiology, clonal evolution, and drug sensitivity or resistance of chronic lymphocytic leukemia (CLL). By performing whole exome sequencing, we present the genetic landscape of primary tumors from TC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7051ecc62dffd4a705e1dc0419aae616
http://wrap.warwick.ac.uk/107495/13/WRAP-exome-sequencing-mouse-model-genetic-disease-Hebenstreit-2018.pdf
http://wrap.warwick.ac.uk/107495/13/WRAP-exome-sequencing-mouse-model-genetic-disease-Hebenstreit-2018.pdf
Autor:
Pischeli Justine, Erika Tissino, Jan Philip Höpner, Alexandre Chigaev, Alexander Egle, Sandra Pennisi, Valter Gattei, Julia Christine Gutjahr, Christine Dierks, Nadja Zaborsky, Richard Greil, Marie Follo, Eva Szenes, Andrea Härzschel, Antonella Zucchetto, Sarah Decker, Tanja Nicole Hartmann
Publikováno v:
Blood. 134:1730-1730
Introduction. Ibrutinib, a small molecule inhibitor of Bruton's tyrosine kinase (BTK), has proven to be an efficient treatment for chronic lymphocytic leukemia (CLL). A distinct characteristic of ibrutinib therapy is transient lymphocytosis. Recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab4b9f30004d74640fb3d9533825d71b
https://doi.org/10.1182/blood-2019-125634
https://doi.org/10.1182/blood-2019-125634