Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jan P. Roesner"'
Autor:
Stefan Bergt, MD, Andrea Grub, MD, Steffen Wagner, MD, Hauke Engelke, MD, Gabriele Nöldge-Schomburg, MD, Brigitte Vollmar, MD, Jan P. Roesner, MD, Nana-Maria Wagner, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 2, Pp 149-159 (2017)
Summary: Cardiac arrest (CA) followed by cardiopulmonary resuscitation (CPR) is associated with high mortality and poor neurological outcome. We compared the effects of pravastatin and simvastatin on survival and neurofunction in a murine model of CA
Externí odkaz:
https://doaj.org/article/b338c5831c814ea4ab0a2baae8efbf3e
Autor:
Andrea Grub, Gabriele Nöldge-Schomburg, Brigitte Vollmar, Hauke Engelke, Stefan Bergt, Steffen Wagner, Jan P. Roesner, Nana-Maria Wagner
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 2, Iss 2, Pp 149-159 (2017)
JACC: Basic to Translational Science, Vol 2, Iss 2, Pp 149-159 (2017)
Visual Abstract
Highlights • In a murine model of CA and CPR, intravenous application of hydrophilic pravastatin resulted in increased survival and neurofunctional outcome. • In contrast, intravenous application of lipophilic simvastatin did
Highlights • In a murine model of CA and CPR, intravenous application of hydrophilic pravastatin resulted in increased survival and neurofunctional outcome. • In contrast, intravenous application of lipophilic simvastatin did
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa101d0a119d121bcdf87ee27ce02a67
http://europepmc.org/articles/PMC6113548
http://europepmc.org/articles/PMC6113548
Autor:
Mandy Otto, Nana-Maria Wagner, Rika Bajorat, Brigitte Vollmar, W. Liu, Jan P. Roesner, J.-C. Eczko
Publikováno v:
Life sciences. 242
Aims Neointimal hyperplasia contributes to arterial restenosis after percutaneous transluminal coronary angioplasty or vascular surgery. Neointimal thickening after arterial injury is determined by inflammatory processes. We investigated the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b53acdb84df25dca1fc9c005bb5de50
https://pubmed.ncbi.nlm.nih.gov/31891724
https://pubmed.ncbi.nlm.nih.gov/31891724
Autor:
Brigitte Vollmar, Tobias Neumann, Andrea Grub, Matthias Gruenewald, Martin Albrecht, Claudia Beltschany, Jan P. Roesner, Patrick Meybohm, Stefan Bergt, Kai Zacharowski
Publikováno v:
Critical Care Medicine. 44:e988-e995
The fibrin-derived peptide Bβ15-42 (FX06) has been proven to attenuate ischemia/reperfusion injury. We tested the hypothesis that Bβ15-42 improves survival rate and neurocognitive recovery after cardiopulmonary resuscitation.Pig and mouse model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108812845bb0f89e1fee518b1e62edc8
https://doi.org/10.1097/ccm.0000000000001860
https://doi.org/10.1097/ccm.0000000000001860
Autor:
Thomas Mittlmeier, Jan P. Roesner, Brigitte Vollmar, Paula Röpenack, Anica Eschler, Kirsten Büsing, Georg Gradl, Kristin Pille, Philipp Herlyn
Publikováno v:
Injury. 46:S17-S23
Introduction Vertebral compression fractures (VCFs) are one of the most common injuries in the aging population presenting with an annual incidence of 1.4 million new cases in Europe. Current treatment strategies focus on cement-associated solutions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981eea25d6cfef3be813f19830a0f6df
https://doi.org/10.1016/s0020-1383(15)30014-0
https://doi.org/10.1016/s0020-1383(15)30014-0
Autor:
Esther Novosel, Georg Matheis, Beate Brock, Peter I. Lelkes, Johan von Grönheim, Brigitte Vollmar, Anne Herbst, Philipp Warnke, Sabine Kischkel, Andreas Podbielski, Jan P. Roesner, Joerg Schneider, Marc-Jonas Epping, Stefan Bergt
Publikováno v:
ASAIO journal (American Society for Artificial Internal Organs : 1992). 63(2)
A side-by-side comparison of the decarboxylation efficacy of two pump-driven venovenous extracorporeal lung assist devices, i.e., a first prototype of the new miniaturized ambulatory extracorporeal membrane ventilator, I-lung versus the commercial sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c5d53375b0146611e1e90e12e50450
https://pubmed.ncbi.nlm.nih.gov/28092273
https://pubmed.ncbi.nlm.nih.gov/28092273
Autor:
Ivan Barilar, Brigitte Vollmar, Rika Bajorat, Melanie Mueller, Stefan Bergt, Nana-Maria Wagner, Andrea Grub, Jan P. Roesner
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 8, p e0220404 (2019)
PLoS ONE, Vol 14, Iss 8, p e0220404 (2019)
BackgroundPatients experiencing cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) often die or suffer from severe neurological impairment. Post resuscitation syndrome is characterized by a systemic inflammatory response. Toll-like receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2502c1a62f05bc9a3b072e01e334d269
https://doi.org/10.1371/journal.pone.0220404
https://doi.org/10.1371/journal.pone.0220404
Autor:
Laura Bierhansl, Gabriele Nöldge-Schomburg, Jan P. Roesner, Brigitte Vollmar, Nana-Maria Wagner
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33:1943-1951
Objective— Toll-like receptor 2 (TLR2) inhibition by function blocking antibodies (ABs) is associated with enhanced preservation of endothelial cell function during vascular disease. In the present study, we investigated the capacity of TLR2-blocki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ae8dde7bc3708be6c6258c9a398801
https://doi.org/10.1161/atvbaha.113.301783
https://doi.org/10.1161/atvbaha.113.301783
Autor:
Thomas Mittlmeier, Robert Rotter, Anica Eschler, Philipp Herlyn, Jan P. Roesner, Georg Gradl, Brigitte Vollmar, Paula Roepenack, Heiner Martin, Martin Reichel
Publikováno v:
BioMed Research International, Vol 2016 (2016)
BioMed Research International
BioMed Research International
Introduction. Current treatment strategies for osteoporotic vertebral compression fractures (VCFs) focus on cement-associated solutions. Complications associated with cement application are leakage, embolism, adjacent fractures, and compromise in bon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213a74958dea3ea8a3b3e07c0e6ecca8
https://doaj.org/article/e4bbb26e8d7f4a9ca9885f354647730d
https://doaj.org/article/e4bbb26e8d7f4a9ca9885f354647730d
Autor:
Stefan Bergt, G. Nöldge-Schomburg, Jan Mersmann, Jan P. Roesner, Carmen Barthuber, Karl Bohnenberg, Kai Zacharowski, Csaba Szabó
Publikováno v:
Shock. 33:507-512
Pharmacological protection from myocardial reperfusion injury, despite plenty of approaches, has still not been realized in humans. We studied the putative infarct size (IS)-sparing capacity of poly(ADP-ribose)polymerase inhibitor, INO-1001, and focu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2276360c4118d019ab5369aa49f07360
https://doi.org/10.1097/shk.0b013e3181c4fb08
https://doi.org/10.1097/shk.0b013e3181c4fb08