Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jan P. Möschwitzer"'
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 1092-1103 (2019)
Drug nanosuspensions/nanocrystals have been recognized as one useful and successful approach for drug delivery. Drug nanocrystals could be further decorated to possess extended functions (such as controlled release) and designed for special in vivo a
Externí odkaz:
https://doaj.org/article/0cb8c8e21313490f94c1f5eb7f4dcea6
Publikováno v:
Drug Development and Industrial Pharmacy. 47:235-245
Cavi-precipitation has the potential to generate drug nanocrystals very efficiently. Achieving smaller than 100 nm particle size for organic drug substances still remained a challenge. The objective of this study was to demonstrate if cavi-precipitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4fca2b034cdc8c4fd465836356a054f
https://doi.org/10.1080/03639045.2020.1871004
https://doi.org/10.1080/03639045.2020.1871004
Publikováno v:
International journal of pharmaceutics. 607
The purpose of this study was to show whether it is possible to prepare sub 100 nm or preferably sub-50 nm drug nanosuspension (NS) of suitable quality for intravenous administration. Furthermore, we have studied how the brain targeting potential of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145510b2f60bc5075618b2a42d785aec
https://pubmed.ncbi.nlm.nih.gov/34371150
https://pubmed.ncbi.nlm.nih.gov/34371150
Publikováno v:
Powder Technology. 332:63-69
Production of nanosuspension for drug bioavailability improvement has been accepted and frequently used in pharmaceutical industry. Normally, the preparation started from crystalline drug. However, some previous studies found that amorphous drug powd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::753234d2be201acc3ed7f28b71a07df6
https://doi.org/10.1016/j.powtec.2018.03.028
https://doi.org/10.1016/j.powtec.2018.03.028
Publikováno v:
Drug Development and Industrial Pharmacy. 44:233-242
Drug nanosuspension is one of the established methods to improve the bioavailability of poorly soluble drugs. Drug physical properties aspect (morphology, solid state, starting size et al) is a critical parameter determining the production efficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8cfa29a712a8a64cc7a999f03ec575e
https://doi.org/10.1080/03639045.2017.1386207
https://doi.org/10.1080/03639045.2017.1386207
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 114:175-185
Treatment of cryptococcal meningitis with antifungals such as itraconazol is difficult due their low concentration in the brain. Therefore, drug carriers with high payload are highly desired. But, generation of itraconazole loaded poly(butyl cyanoacr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cadc3d13f1342cb286875092b55079d
https://doi.org/10.1016/j.ejpb.2017.01.014
https://doi.org/10.1016/j.ejpb.2017.01.014
Publikováno v:
Drug Delivery
Drug Delivery, Vol 26, Iss 1, Pp 1092-1103 (2019)
Drug Delivery, Vol 26, Iss 1, Pp 1092-1103 (2019)
Drug nanosuspensions/nanocrystals have been recognized as one useful and successful approach for drug delivery. Drug nanocrystals could be further decorated to possess extended functions (such as controlled release) and designed for special in vivo a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07cc83e367a6a1e2c4f1cb33cfb3820
https://doi.org/10.17169/refubium-26272
https://doi.org/10.17169/refubium-26272
Publikováno v:
Pharmaceutical nanotechnology. 7(2)
Background: Miniaturization of nanosuspensions preparation is a necessity in order to enable proper formulation screening before nanosizing can be performed on a large scale. Ideally, the information generated at small scale is predictive for large s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8866c1a60634b4d3b439f138bbeb5d07
https://pubmed.ncbi.nlm.nih.gov/31271122
https://pubmed.ncbi.nlm.nih.gov/31271122
Publikováno v:
AAPS PharmSciTech. 18:1683-1691
Nanosizing is frequently used as formulation approach to increase the bioavailability of poorly water-soluble drugs. However, standard size reduction processes can be relatively time-consuming. It was found that the modification of the physical prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81184b76e92ec0080c8dd943cc1eee77
https://doi.org/10.1208/s12249-016-0612-1
https://doi.org/10.1208/s12249-016-0612-1
Publikováno v:
European Journal of Pharmaceutical Sciences. 78:121-131
Itraconazole is a poorly soluble drug which is used in the treatment of systemic fungal infections. However, there is little reported literature about itraconazole loaded delivery systems used for targeted delivery. Therefore, poly(butyl cyanoacrylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c191ebfe5dc2badfe954287b8f9a244
https://doi.org/10.1016/j.ejps.2015.07.010
https://doi.org/10.1016/j.ejps.2015.07.010