A Novel Topical PPARγ Agonist Induces PPARγ Activity in Ulcerative Colitis Mucosa and Prevents and Reverses Inflammation in Induced Colitis Models

Autor: Jan P Mattson, Åsa V. Keita, Vassilia Theodorou, Ingrid Påhlman, Johan D. Söderholm, Sven Påhlman, Sofie Mohlin, Stéphanie Da Silva

Publikováno v: Inflammatory Bowel Diseases
Inflammatory Bowel Diseases, Lippincott, Williams & Wilkins, 2018, 24 (4), pp.792-805. ⟨10.1093/ibd/izx079⟩

International audience; Background: Peroxisome proliferator-activated receptor-gamma (PPAR gamma) exerts anti-inflammatory effects and is therefore a potential target in ulcerative colitis (UC). A novel PPAR. agonist (AS002) developed for local actio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035caee86726c54d7124a8adae61403c
https://doi.org/10.1093/ibd/izx079