Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Jan Oppelt"'
Autor:
Monica Medappa, Petra Pospíšilová, Maria Paula M Madruga, Lucy N John, Camila G Beiras, Linda Grillová, Jan Oppelt, Arka Banerjee, Marti Vall-Mayans, Oriol Mitjà, David Šmajs
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 1, p e0011831 (2024)
Yaws is an endemic disease caused by Treponema pallidum subsp. pertenue (TPE) that primarily affects children in rural regions of the tropics. The endemic character of yaws infections and the expected exclusive reservoir of TPE in humans opened a new
Externí odkaz:
https://doaj.org/article/5de5c8d878a0413eafb794021ac9d5a0
Autor:
Canan Celiker, Kamila Weissova, Katerina Amruz Cerna, Jan Oppelt, Birthe Dorgau, Francisco Molina Gambin, Jana Sebestikova, Majlinda Lako, Evelyne Sernagor, Petra Liskova, Tomas Barta
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107237- (2023)
Summary: Cells in the human retina must rapidly adapt to constantly changing visual stimuli. This fast adaptation to varying levels and wavelengths of light helps to regulate circadian rhythms and allows for adaptation to high levels of illumination,
Externí odkaz:
https://doaj.org/article/48be5d364d3d4c5b8aa4e6d35bf1910a
Autor:
Tanja Limberger, Michaela Schlederer, Karolina Trachtová, Ines Garces de los Fayos Alonso, Jiaye Yang, Sandra Högler, Christina Sternberg, Vojtech Bystry, Jan Oppelt, Boris Tichý, Margit Schmeidl, Petra Kodajova, Anton Jäger, Heidi A. Neubauer, Monika Oberhuber, Belinda S. Schmalzbauer, Sarka Pospisilova, Helmut Dolznig, Wolfgang Wadsak, Zoran Culig, Suzanne D. Turner, Gerda Egger, Sabine Lagger, Lukas Kenner
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-19 (2022)
Abstract Background Frequent truncation mutations of the histone lysine N-methyltransferase KMT2C have been detected by whole exome sequencing studies in various cancers, including malignancies of the prostate. However, the biological consequences of
Externí odkaz:
https://doaj.org/article/5aaf49f7c7c74c4eb49241877d305439
Autor:
Huan-Chang Liang, Mariantonia Costanza, Nicole Prutsch, Mark W. Zimmerman, Elisabeth Gurnhofer, Ivonne A. Montes-Mojarro, Brian J. Abraham, Nina Prokoph, Stefan Stoiber, Simone Tangermann, Cosimo Lobello, Jan Oppelt, Ioannis Anagnostopoulos, Thomas Hielscher, Shahid Pervez, Wolfram Klapper, Francesca Zammarchi, Daniel-Adriano Silva, K. Christopher Garcia, David Baker, Martin Janz, Nikolai Schleussner, Falko Fend, Šárka Pospíšilová, Andrea Janiková, Jacqueline Wallwitz, Dagmar Stoiber, Ingrid Simonitsch-Klupp, Lorenzo Cerroni, Stefano Pileri, Laurence de Leval, David Sibon, Virginie Fataccioli, Philippe Gaulard, Chalid Assaf, Fabian Knörr, Christine Damm-Welk, Wilhelm Woessmann, Suzanne D. Turner, A. Thomas Look, Stephan Mathas, Lukas Kenner, Olaf Merkel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Anaplastic large cell lymphoma (ALCL) is an aggressive T-cell lymphoma often with poor prognosis. To identify genes defining ALCL cell state and dependencies, the authors here characterize ALCL-specific super-enhancers and describe the BATF3/IL-2R−
Externí odkaz:
https://doaj.org/article/6005c21ca6e84b989b1eb0469795a79b
Autor:
Eliška Vrbová, Angel A Noda, Linda Grillová, Islay Rodríguez, Allyn Forsyth, Jan Oppelt, David Šmajs
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 6, p e0009900 (2022)
Bejel (endemic syphilis) is a neglected non-venereal disease caused by Treponema pallidum subsp. endemicum (TEN). Although it is mostly present in hot, dry climates, a few cases have been found outside of these areas. The aim of this work was the seq
Externí odkaz:
https://doaj.org/article/c8a7df6507d44dafa585ceaa9be45fc1
Autor:
Petra Bencurova, Jiri Baloun, Jakub Hynst, Jan Oppelt, Hana Kubova, Sarka Pospisilova, Milan Brazdil
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Temporal lobe epilepsy (TLE) is the most common epilepsy type. TLE onset in infancy aggravates features like severity, drug responsiveness, or development of comorbidities. These aggravations may arise from altered micro RNA (miRNA) expressi
Externí odkaz:
https://doaj.org/article/9db2b901db6249209f30744cba479bd3
Autor:
Marie Klumplerova, Petra Splichalova, Jan Oppelt, Jan Futas, Aneta Kohutova, Petra Musilova, Svatava Kubickova, Roman Vodicka, Ludovic Orlando, Petr Horin
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-15 (2020)
Abstract Background The mammalian Major Histocompatibility Complex (MHC) is a genetic region containing highly polymorphic genes with immunological functions. MHC class I and class II genes encode antigen-presenting molecules expressed on the cell su
Externí odkaz:
https://doaj.org/article/4720e29c4052485e985df456e88ad60c
Autor:
Linda Grillová, Matthew T Robinson, Anisone Chanthongthip, Antony T Vincent, Cecilia Nieves, Jan Oppelt, Jean-François Mariet, Céline Lorioux, Manivanh Vongsouvath, Mayfong Mayxay, Ooyanong Phonemeexay, Sayaphet Rattanavong, Koukeo Phommasone, Anousone Douangnouvong, David Šmajs, Frédéric J Veyrier, Paul N Newton, Mathieu Picardeau
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 12, p e0010076 (2021)
BackgroundAlthough Southeast Asia is one of the most leptospirosis afflicted regions, little is known about the diversity and molecular epidemiology of the causative agents of this widespread and emerging zoonotic disease.Methodology/principal findin
Externí odkaz:
https://doaj.org/article/0ad162bfa4744d08932402642dd3d87e
Autor:
Idrissa S. Chuma, Christian Roos, Anagaw Atickem, Torsten Bohm, D. Anthony Collins, Linda Grillová, Luisa K. Hallmaier-Wacker, Rudovick R. Kazwala, Julius D. Keyyu, Simone Lüert, Ulrich Maloueki, Jan Oppelt, Klára J. Petrželková, Alexander Piel, Fiona A. Stewart, David Šmajs, Sascha Knauf
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Abstract In our most recent study, we found that in Tanzania infection with Treponema pallidum (TP) subsp. pertenue (TPE) is present in four different monkey species. In order to gain information on the diversity and epidemiological spread of the inf
Externí odkaz:
https://doaj.org/article/f8c164691259480489fa429dfbf414e4
Autor:
Michael Bartos, Frantisek Siegl, Alena Kopkova, Lenka Radova, Jan Oppelt, Marek Vecera, Tomas Kazda, Radim Jancalek, Michal Hendrych, Marketa Hermanova, Petra Kasparova, Zuzana Pleskacova, Vaclav Vybihal, Pavel Fadrus, Martin Smrcka, Radek Lakomy, Radim Lipina, Tomas Cesak, Ondrej Slaby, Jiri Sana
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioblastoma (GBM) is the most frequently occurring primary malignant brain tumor of astrocytic origin. To change poor prognosis, it is necessary to deeply understand the molecular mechanisms of gliomagenesis and identify new potential biomarkers and
Externí odkaz:
https://doaj.org/article/94d22527aabb4477a1afa411c71b7e62