Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jan O. Secher"'
Autor:
Kristine K. Freude, Troels Tolstrup Nielsen, Bjørn Holst, Morten Juhl, Kaveh Mashayekhi, Vanessa Jane Hall, Dong Li, Poul Hyttel, Jan O. Secher
Publikováno v:
Cell Cycle. 16:1070-1084
Previous research has shown that a subpopulation of cells within cultured human dermal fibroblasts, termed multilineage-differentiating stress enduring (Muse) cells, are preferentially reprogrammed into induced pluripotent stem cells. However, contro
Autor:
Miriam Kolko, Poul Hyttel, Kristine K. Freude, Jan O. Secher, Vanessa Jane Hall, Dong Li, Marilin Ivask
Physiologically and anatomically, humans and pigs share many similarities, which make porcine induced pluripotent stem cells (piPSCs) very attractive for modeling human cell therapy as well as for testing safety of iPSC based cell replacement therapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e4577bea8183613eabc1356823448b
https://europepmc.org/articles/PMC6300098/
https://europepmc.org/articles/PMC6300098/
Publikováno v:
Reproduction, Fertility and Development. 33:119
Trophectoderm (TE) biopsying for single nucleotide polymorphisms (SNPs) analysis is being implemented as a tool for the selection of elite bovine embryos. This biopsy method renders ample cells for analysis without compromising the inner cell mass (I
Publikováno v:
Secher, J, Callesen, H, Freude, K K & Hyttel, P 2016, ' Initial embryology and pluripotent stem cells in the pig-the quest for establishing the pig as a model for cell therapy ', Theriogenology, vol. 85, no. 1, pp. 162-171 . https://doi.org/10.1016/j.theriogenology.2015.09.017
The quest for porcine pluripotent stem cells (PSCs) was initiated in the early 90s. Initially, it was the intention to benefit from these cells for production of genetically modified pigs using homologous recombination followed by derivation of chime
Autor:
Emma Lorenzen, Anja Weinreich Olsen, Frank Follmann, Gregers Jungersen, Hannah Louise Zakariassen, Sandra Goericke-Pesch, Peter Andersen, Mette Sif Hansen, Jørgen S. Agerholm, Jan O. Secher
Publikováno v:
Lorenzen, E, Follmann, F, Secher, J O, Goericke-Pesch, S K, Hansen, M S, Zakariassen, H, Olsen, A W, Andersen, P, Jungersen, G & Agerholm, J S 2017, ' Intrauterine inoculation of minipigs with Chlamydia trachomatis during diestrus establishes a longer lasting infection compared to vaginal inoculation during estrus ', Microbes and Infection, vol. 19, no. 6, pp. 334-342 . https://doi.org/10.1016/j.micinf.2017.01.008
Lorenzen, E, Follmann, F, Secher, J O, Goericke-Pesch, S, Hansen, M S, Zakariassen, H, Weinreich Olsen, A, Andersen, P, Jungersen, G & Agerholm, J S 2017, ' Intrauterine inoculation of minipigs with Chlamydia trachomatis during diestrus establishes a longer lasting infection compared to vaginal inoculation during estrus ', Microbes and Infection, vol. 19, no. 6, pp. 334-342 . https://doi.org/10.1016/j.micinf.2017.01.008
Lorenzen, E, Follmann, F, Secher, J O, Goericke-Pesch, S, Hansen, M S, Zakariassen, H, Weinreich Olsen, A, Andersen, P, Jungersen, G & Agerholm, J S 2017, ' Intrauterine inoculation of minipigs with Chlamydia trachomatis during diestrus establishes a longer lasting infection compared to vaginal inoculation during estrus ', Microbes and Infection, vol. 19, no. 6, pp. 334-342 . https://doi.org/10.1016/j.micinf.2017.01.008
Advanced animal models, such as minipigs, are needed for the development of a globally requested human Chlamydia vaccine. Previous studies have shown that vaginal inoculation of sexually mature Göttingen minipigs with Chlamydia trachomatis resulted
Autor:
Jacob F. Bentzon, Charlotte Brandt Sørensen, Jan O. Secher, Yonglun Luo, Henrik Callesen, Ying Liu, Mette Schmidt, Stoyan G. Petkov, Dong Li, Kristine K. Freude, Vanessa Jane Hall, Poul Hyttel
Publikováno v:
Secher, J, Liu, Y, Petkov, S, Luo, Y, Li, D, Hall, V J, Schmidt, M, Callesen, H, Bentzon, J F, Sørensen, C B, Freude, K K & Hyttel, P 2017, ' Evaluation of porcine stem cells competence for somatic cell nuclear transfer and production of cloned animals ', Animal Reproduction Science, vol. 178, pp. 40-49 . https://doi.org/10.1016/j.anireprosci.2017.01.007
Porcine somatic cell nuclear transfer (SCNT) has been used extensively to create genetically modified pigs, but the efficiency of the methodology is still low. It has been hypothesized that pluripotent or multipotent stem cells might result in increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82655d11d2b48f2a62ea005614effbd0
https://pure.au.dk/portal/da/publications/evaluation-of-porcine-stem-cells-competence-for-somatic-cell-nuclear-transfer-and-production-of-cloned-animals(80f11a98-9a07-4920-91b2-1e242f33f6f5).html
https://pure.au.dk/portal/da/publications/evaluation-of-porcine-stem-cells-competence-for-somatic-cell-nuclear-transfer-and-production-of-cloned-animals(80f11a98-9a07-4920-91b2-1e242f33f6f5).html
Autor:
Haja N. Kadarmideen, Henrik Callesen, Gianluca Mazzoni, Hanne Skovsgaard Pedersen, Poul Hyttel, Lotte Stroebech, Kristine K. Freude, Eduardo M. Razza, Jan O. Secher
Publikováno v:
Mazzoni, G, Razza, E, Pedersen, H S, Secher, J, Kadarmideen, H, Callesen, H, Strøbech, L, Freude, K K & Hyttel, P 2017, ' In vitro production of bovine embryos: cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence ', Animal Reproduction, vol. 14, no. 3, pp. 482-489 . https://doi.org/10.21451/1984-3143-AR990
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2022-04-29T08:45:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01 In vitro production (IVP) of bovine embryos has become widespread technology implemented in cattle breeding and production. Here, we review n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4219f29194efd4ddb0cbc6ede538f7d3
https://pure.au.dk/portal/da/publications/in-vitro-production-of-bovine-embryos-cumulusgranulosa-cell-gene-expression-patterns-point-to-early-atresia-as-beneficial-for-oocyte-competence(b6076cce-cb1b-458a-ac4a-abda63985778).html
https://pure.au.dk/portal/da/publications/in-vitro-production-of-bovine-embryos-cumulusgranulosa-cell-gene-expression-patterns-point-to-early-atresia-as-beneficial-for-oocyte-competence(b6076cce-cb1b-458a-ac4a-abda63985778).html
Autor:
J. Docherty, N. Hashem, Poul Hyttel, J. H. Pryor, Marilin Ivask, B. Avery, Lotte Strøbech, Charles R. Long, Jan O. Secher
Publikováno v:
Reproduction, Fertility and Development. 30:202
Optimal bovine in vitro oocyte maturation (IVM) is a prerequisite for subsequent optimal blastocyst rates. Ovum pick-up (OPU), by which cumulus–oocyte complexes (COC) are collected in vivo, is performed outside a laboratory and often requires IVM t
Publikováno v:
Secher, J, Freude, K, Li, R & Callesen, H 2015, ' Optimization of three-dimensional imaging on in vitro produced porcine blastocysts and chimeras for stem cell testing: A technology report ', Stem Cells and Development, vol. 24, pp. 1141-1145 . https://doi.org/10.1089/scd.2014.0503
Differential staining is an immunocytochemical staining that visualizes trophectoderm (TE) and the inner cell mass (ICM) of the blastocysts. It is used to determine the blastocyst quality, but could also be a useful tool to assess the integration sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e246020c22fec715035185a21c2d99
https://pure.au.dk/portal/da/publications/optimization-of-threedimensional-imaging-on-in-vitro-produced-porcine-blastocysts-and-chimeras-for-stem-cell-testing-a-technology-report(ecda0500-d9cd-4d9f-ae69-526e5569f4c9).html
https://pure.au.dk/portal/da/publications/optimization-of-threedimensional-imaging-on-in-vitro-produced-porcine-blastocysts-and-chimeras-for-stem-cell-testing-a-technology-report(ecda0500-d9cd-4d9f-ae69-526e5569f4c9).html
Autor:
N. Hashem, C. R. Looney, J. H. Pryor, Lotte Stroebech, Charles R. Long, B. Avery, Jan O. Secher, Poul Hyttel
Publikováno v:
Reproduction, Fertility and Development. 29:179
Laboratory ware for the in vitro-produced embryos is generally made from embryo-tested plastic instead of glass. The quality of the plastic is crucial for the outcome because plastic is often toxic to gametes (Nijs et al. 2009 Fertil. Steril. 92, 527