Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jan Nagenborg"'
Autor:
Han Jin, Cheng Zhang, Jan Nagenborg, Peter Juhasz, Adele V. Ruder, Cornelis J. J. M. Sikkink, Barend M. E. Mees, Olivia Waring, Judith C. Sluimer, Dietbert Neumann, Pieter Goossens, Marjo M. P. C. Donners, Adil Mardinoglu, Erik A. L. Biessen
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background Metabolism is increasingly recognized as a key regulator of the function and phenotype of the primary cellular constituents of the atherosclerotic vascular wall, including endothelial cells, smooth muscle cells, and inflammatory c
Externí odkaz:
https://doaj.org/article/abf30882fa56414492f4965ea2f6957e
Autor:
Jan Nagenborg, Han Jin, Adele V. Ruder, Lieve Temmerman, Barend Mees, Casper Schalkwijk, Daniel Müller-Klieser, Thorsten Berg, Pieter Goossens, Marjo M. P. C. Donners, Erik A. L. Biessen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionInhibition of STAT5 was recently reported to reduce murine atherosclerosis. However, the role of STAT5 isoforms, and more in particular STAT5A in macrophages in the context of human atherosclerosis remains unknown.Methods and resultsHere,
Externí odkaz:
https://doaj.org/article/206556e531ef4ffba0deaedda5baeca5
Autor:
Adele V. Ruder, Lieve Temmerman, Joep M.A. van Dommelen, Jan Nagenborg, Chang Lu, Judith C. Sluimer, Pieter Goossens, Erik A.L. Biessen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Macrophages (MΦ) are commonly cultured in vitro as a model of their biology and functions in tissues. Recent evidence suggests MΦ to engage in quorum sensing, adapting their functions in response to cues about the proximity of neighboring cells. Ho
Externí odkaz:
https://doaj.org/article/47b579081a8041bf973af134d1fc3d2b
Autor:
Olivia J. Waring, Han Jin, Jan Nagenborg, Pieter Goossens, Marjo M.P.C. Donners, Erik A.L. Biessen
Publikováno v:
EJVES Vascular Forum, Vol 48, Iss , Pp 51-52 (2020)
Externí odkaz:
https://doaj.org/article/7534514b9c6a4bcd99a421ca73522c13
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2419
Transfection of murine primary macrophages to silence genes can be a challenging procedure because this cell type has developed mechanisms to evade cellular intrusion. The introduction of small interfering RNA (siRNA) encapsulated in liposomes to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce9d2fdf4607aa13ecc8e46e9e1ca242
https://pubmed.ncbi.nlm.nih.gov/35237962
https://pubmed.ncbi.nlm.nih.gov/35237962
Publikováno v:
European Journal of Pharmacology, 816, 14-24. Elsevier Science
European Journal of Pharmacology
European journal of pharmacology 816, 14-24 (2017). doi:10.1016/j.ejphar.2017.10.005
NARCIS
Publikationsserver der RWTH Aachen University
European Journal of Pharmacology
European journal of pharmacology 816, 14-24 (2017). doi:10.1016/j.ejphar.2017.10.005
NARCIS
Publikationsserver der RWTH Aachen University
Macrophages are key players in atherosclerotic lesions, regulating the local inflammatory milieu and plaque stability by the secretion of many inflammatory molecules, growth factors and cytokines. Monocytes have long been considered to be the main so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb63e93d54adff543b908f00730fc46
https://cris.maastrichtuniversity.nl/en/publications/792b81e7-31a7-4a78-bed6-45ffc45be911
https://cris.maastrichtuniversity.nl/en/publications/792b81e7-31a7-4a78-bed6-45ffc45be911
