Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Jan Mojzis"'
Autor:
Peter Kubatka, Alena Mazurakova, Lenka Koklesova, Tomas Kuruc, Marek Samec, Karol Kajo, Klaudia Kotorova, Marian Adamkov, Karel Smejkal, Emil Svajdlenka, Dana Dvorska, Dusan Brany, Eva Baranovicova, Vladimira Sadlonova, Jan Mojzis, Martin Kello
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Based on extensive data from oncology research, the use of phytochemicals or plant-based nutraceuticals is considered an innovative tool for cancer management. This research aimed to analyze the oncostatic properties of Salvia officinal
Externí odkaz:
https://doaj.org/article/c3662297b57548de96e5359613f70678
Autor:
Radka Michalkova, Ladislav Mirossay, Martin Kello, Gabriela Mojzisova, Janette Baloghova, Anna Podracka, Jan Mojzis
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10354 (2023)
There is no doubt that significant progress has been made in tumor therapy in the past decades. However, the discovery of new molecules with potential antitumor properties still remains one of the most significant challenges in the field of anticance
Externí odkaz:
https://doaj.org/article/e633fa2635e74186b145221411c8ddfa
Autor:
Radka Michalkova, Martin Kello, Martina Cizmarikova, Annamaria Bardelcikova, Ladislav Mirossay, Jan Mojzis
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5964 (2023)
Colorectal (CRC) and gastric cancers (GC) are the most common digestive tract cancers with a high incidence rate worldwide. The current treatment including surgery, chemotherapy or radiotherapy has several limitations such as drug toxicity, cancer re
Externí odkaz:
https://doaj.org/article/775e2edffc94443296805d989ba99224
Autor:
Martin Kello, Michal Goga, Klaudia Kotorova, Dominika Sebova, Richard Frenak, Ludmila Tkacikova, Jan Mojzis
Publikováno v:
Plants, Vol 12, Iss 3, p 611 (2023)
Lichen metabolites represent a wide range of substances with a variety of biological effects. The present study was designed to analyze the potential antiproliferative, antimicrobial and antioxidative effects of several extracts from lichens (Pseudev
Externí odkaz:
https://doaj.org/article/6526f4aea2bb4dbe9ad03a5eaffcc35d
Publikováno v:
Molecules, Vol 28, Iss 1, p 251 (2022)
This work deals with the study of the synthesis of new bis-indole analogues with a phenyl linker derived from indole phytoalexins. Synthesis of target bis-indole thiourea linked by a phenyl linker was achieved by the reaction of [1-(tert-butoxycarbon
Externí odkaz:
https://doaj.org/article/0aa5a1d1dc014509b5b2fef3b88fb5e3
Autor:
Maria Gazdova, Radka Michalkova, Martin Kello, Maria Vilkova, Zuzana Kudlickova, Janette Baloghova, Ladislav Mirossay, Jan Mojzis
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12266 (2022)
This study was focused on investigating the antiproliferative effects of chalcone hybrids in melanoma cancer cells. Among seven chalcone hybrids, the chalcone-acridine hybrid 1C was the most potent and was selected for further antiproliferative mecha
Externí odkaz:
https://doaj.org/article/d9460624bc2c47a4b76a9623fe4ca2f0
Autor:
Radka Michalkova, Martin Kello, Zuzana Kudlickova, Maria Gazdova, Ladislav Mirossay, Gabriela Mojzisova, Jan Mojzis
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 503 (2022)
Although new chemotherapy significantly increased the survival of breast cancer (BC) patients, the use of these drugs is often associated with serious toxicity. The discovery of novel anticancer agents for BC therapy is expected. This study was condu
Externí odkaz:
https://doaj.org/article/4ee940a16baa47fabf8e4f3b74d020e1
Autor:
Martin Kello, Tomas Kuruc, Klaudia Petrova, Michal Goga, Zuzana Michalova, Matus Coma, Dajana Rucova, Jan Mojzis
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2173 (2021)
Acute lymphoblastic leukemia (ALL) is the most frequently diagnosed type of leukemia among children. Although chemotherapy is a common treatment for cancer, it has a wide range of serious side effects, including myelo- and immunosuppression, hepatoto
Externí odkaz:
https://doaj.org/article/00260bad5aa74e77b306832ff6761761
Autor:
Jozef Hudec, Jan Mojzis, Marta Habanova, Jorge A. Saraiva, Pavel Hradil, Tibor Liptaj, Lubomir Kobida, Miroslav Haban, Maria Holovicova, Dominika Zvercova
Publikováno v:
Applied Sciences, Vol 11, Iss 11, p 5300 (2021)
Sarcopoterium spinosum (L.) is a medicinal plant traditionally used for the treatment of various diseases including cancer in the Near- and Middle East. The fractions and constituents of the ethanol extract of S. spinosum were screened for in vitro c
Externí odkaz:
https://doaj.org/article/b2383d88fb6f48e79fd5cddc40a3b252
Publikováno v:
Cancers, Vol 13, Iss 11, p 2730 (2021)
Although great progress has been made in the treatment of cancer, the search for new promising molecules with antitumor activity is still one of the greatest challenges in the fight against cancer due to the increasing number of new cases each year.
Externí odkaz:
https://doaj.org/article/2bddc990259a450081fd1ae1c87d5dba