Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jan Mojžíš"'
Autor:
Dana Dvorska, Alena Mazurakova, Lenka Lackova, Dominika Sebova, Karol Kajo, Marek Samec, Dusan Brany, Emil Svajdlenka, Jakub Treml, Sandra Mersakova, Jan Strnadel, Marian Adamkov, Zora Lasabova, Kamil Biringer, Jan Mojzis, Dietrich Büsselberg, Karel Smejkal, Martin Kello, Peter Kubatka
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionWithin oncology research, there is a high effort for new approaches to prevent and treat cancer as a life-threatening disease. Specific plant species that adapt to harsh conditions may possess unique properties that may be utilized in the
Externí odkaz:
https://doaj.org/article/712cfb8a7251426ca7c5229d02600bef
Autor:
Monika Garberová, Zuzana Kudličková, Radka Michalková, Monika Tvrdoňová, Danica Sabolová, Slávka Bekešová, Michal Gramblička, Ján Mojžiš, Mária Vilková
Publikováno v:
Molecules, Vol 29, Iss 14, p 3387 (2024)
This study focuses on the synthesis and structural characterization of new compounds that integrate thiazolidine-2,4-dione, acridine moiety, and an acetamide linker, aiming to leverage the synergistic effects of these pharmacophores for enhanced ther
Externí odkaz:
https://doaj.org/article/338bd1247f564816bfc5ddb0335c0bb4
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7541 (2024)
Ovarian cancer ranks among the most severe forms of cancer affecting the female reproductive organs, posing a significant clinical challenge primarily due to the development of resistance to conventional therapies. This study investigated the effects
Externí odkaz:
https://doaj.org/article/e95e7d5063b0414380db846194d52135
Publikováno v:
Inorganics, Vol 12, Iss 7, p 177 (2024)
The gallium(III) complex of warfarin was synthesized, and its structure was determined by means of theoretical, analytical, and spectral analyses. Significant differences in the IR and Raman spectra of the complex were observed as compared to the spe
Externí odkaz:
https://doaj.org/article/0ff6c1995a574b7398a305888e19c441
Autor:
Peter Kubatka, Alena Mazurakova, Lenka Koklesova, Tomas Kuruc, Marek Samec, Karol Kajo, Klaudia Kotorova, Marian Adamkov, Karel Smejkal, Emil Svajdlenka, Dana Dvorska, Dusan Brany, Eva Baranovicova, Vladimira Sadlonova, Jan Mojzis, Martin Kello
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Based on extensive data from oncology research, the use of phytochemicals or plant-based nutraceuticals is considered an innovative tool for cancer management. This research aimed to analyze the oncostatic properties of Salvia officinal
Externí odkaz:
https://doaj.org/article/c3662297b57548de96e5359613f70678
Publikováno v:
Molecules, Vol 29, Iss 10, p 2388 (2024)
Indole phytoalexins, found in economically significant Cruciferae family plants, are synthesized in response to pathogen attacks or stress, serving as crucial components of plant defense mechanisms against bacterial and fungal infections. Furthermore
Externí odkaz:
https://doaj.org/article/5730044bc41f48c1a2946a69fdbda6cb
Publikováno v:
Molecules, Vol 29, Iss 8, p 1773 (2024)
Ovarian cancer, a highly lethal malignancy among reproductive organ cancers, poses a significant challenge with its high mortality rate, particularly in advanced-stage cases resistant to platinum-based chemotherapy. This study explores the potential
Externí odkaz:
https://doaj.org/article/f76045b6bf87475b9593aec56945c774
Autor:
Ľudmila Balážová, Slavomír Kurhajec, Martin Kello, Zdenka Bedlovičová, Martina Zigová, Eva Petrovová, Katarína Beňová, Ján Mojžiš, Jarmila Eftimová
Publikováno v:
Life, Vol 12, Iss 5, p 767 (2022)
Phellodendron amurense Rupr. is medicinal plant used for supplemental therapy of various diseases based on their positive biological activities. The aim of this study was evaluated the main metabolite, safety of application and anticancer potential.
Externí odkaz:
https://doaj.org/article/62acc310bc1e47b38868e48f553f97de
Autor:
Peter Krammer, Marcel Kvassay, Ján Mojžiš, Martin Kenyeres, Miloš Očkay, Ladislav Hluchý, Ľuboš Pavlov, Ľuboš Skurčák
Publikováno v:
Future Internet, Vol 14, Iss 4, p 99 (2022)
This paper addresses the regression modeling of local environmental pollution levels for electric power industry needs, which is fundamental for the proper design and maintenance of high-voltage transmission lines and insulators in order to prevent v
Externí odkaz:
https://doaj.org/article/7f17af576b6043ddb7d839103fe85403
Autor:
Radka Michalkova, Martin Kello, Zuzana Kudlickova, Maria Gazdova, Ladislav Mirossay, Gabriela Mojzisova, Jan Mojzis
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 503 (2022)
Although new chemotherapy significantly increased the survival of breast cancer (BC) patients, the use of these drugs is often associated with serious toxicity. The discovery of novel anticancer agents for BC therapy is expected. This study was condu
Externí odkaz:
https://doaj.org/article/4ee940a16baa47fabf8e4f3b74d020e1