Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jan Mazerski"'
Autor:
JAN MAZERSKI
Publikováno v:
TASK Quarterly, Vol 5, Iss 3 (2001)
The computer modelling and simulation methods are widely used in rational drug design to obtain information necessary for understanding interactions between a ligand (drug molecule) and its cellular macromolecular target on molecular level. The deter
Externí odkaz:
https://doaj.org/article/707094d1ece347c9add3bddc032608d2
Autor:
JAN MAZERSKI, EDWARD BOROWSKI
Publikováno v:
TASK Quarterly, Vol 2, Iss 4 (1998)
In this paper we present our approaches and results concerning application of molecular modelling techniques in the design of new chemotherapeutic agents for the control of eukariotic systems, comprising compounds for the treatment of systemic fungal
Externí odkaz:
https://doaj.org/article/cc4e9ab90f21443ea18bd6e1ac3d547a
Autor:
Paulina Gwarda, Jan Mazerski, Tomasz Laskowski, Zofia Gdaniec, Jakub Grynda, Witold Andrałojć
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Triazoloacridinone C-1305, a potent antitumor agent recommended for Phase I clinical trials, exhibits high activity towards a wide range of experimental colon carcinomas, in many cases associated with complete tumor regression. C-1305 is a well-estab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a821612a66da3dddff735ead9f0fae18
https://doi.org/10.1038/s41598-020-68609-8
https://doi.org/10.1038/s41598-020-68609-8
Publikováno v:
Ecology and Evolution
Environmental pollution, for example with metals, can significantly affect the ecosystem balance leading to severe changes. Biologically active pigments are relevant for the appearance and condition of birds. Melanin and carotenoid particles are the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7fd61c8aa3efb7f66d1edc05dc8658
http://europepmc.org/articles/PMC6106159
http://europepmc.org/articles/PMC6106159
Publikováno v:
Journal of Molecular Structure. 1141:357-367
Imidazoacridinone C-1311 (Symadex ® ) is an antitumor agent which has been recommended for Phase II clinical trials a few years ago. Previously, it was shown experimentally that during the initial stage of its action C-1311 forms stable intercalatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06fb4aa948ce282ba678d1056549e268
https://doi.org/10.1016/j.molstruc.2017.03.115
https://doi.org/10.1016/j.molstruc.2017.03.115
Publikováno v:
Chemosphere. 203
Over the years, noticeable effort has been directed towards contaminant determination in multiple biotic samples collected from the inhabitants of the Arctic. Little consideration has been given to polar herbivores, however, especially those from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0599161fecef934c2f42619ff2f5a1b3
https://pubmed.ncbi.nlm.nih.gov/29621677
https://pubmed.ncbi.nlm.nih.gov/29621677
Publikováno v:
Postępy Higieny i Medycyny Doświadczalnej, Vol 65, Pp 236-269 (2011)
Postępy Higieny i Medycyny Doświadczalnej, Vol 65, Pp 263-269 (2011)
Postępy Higieny i Medycyny Doświadczalnej, Vol 65, Pp 263-269 (2011)
Akrydyny należą do grupy policyklicznych związków heteroaromatycznych. Wykazują szeroki zakres aktywności biologicznej obejmujący aktywność przeciwpierwotniakową, przeciwbakteryjną, przeciwwirusową i przeciwnowotworową. Pochodne akrydyny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf4690efd018ec969cfe9010dd6e70c
http://journals.indexcopernicus.com/fulltxt.php?ICID=941519
http://journals.indexcopernicus.com/fulltxt.php?ICID=941519
Publikováno v:
Journal of biomolecular structuredynamics. 34(3)
Imidazoacridinone C-1311 (Symadex®) is a powerful antitumor agent, which successfully made its way through the Phase I clinical trials and has been recommended for Phase II few a years ago. It has been shown experimentally that during the initial st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7feabaa2ec3561c2783ba3c8412d5645
https://pubmed.ncbi.nlm.nih.gov/26211888
https://pubmed.ncbi.nlm.nih.gov/26211888
Publikováno v:
European Journal of Medicinal Chemistry. 40:321-328
Synthetic antitumor anthracenedione drugs, in contrast to anthracycline antibiotics, are ineffective in free radical formation in NADH dehydrogenase system. Our results have indicated that neither the reduction potential nor the side chain conformati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb14fea2c666ee626974ceb7f37e5e9f
https://doi.org/10.1016/j.ejmech.2004.10.005
https://doi.org/10.1016/j.ejmech.2004.10.005
Publikováno v:
Advances in Environmental Research. 8:337-349
The paper presents monitoring results and environmental pollution assessment for Gdansk–Sopot–Gdynia Tricity (Poland). Precipitation samples were collected at ten sites in monthly cycles over a period of 4 years from January 1, 1998 to December 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::268626ba64c5ac76b48199aa9e4c93fc
https://doi.org/10.1016/s1093-0191(02)00107-7
https://doi.org/10.1016/s1093-0191(02)00107-7