Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jan Marie Cheng"'
Autor:
Johanna M Jansen, Charles Wartchow, Wolfgang Jahnke, Susan Fong, Tiffany Tsang, Keith Pfister, Tatiana Zavorotinskaya, Dirksen Bussiere, Jan Marie Cheng, Kenneth Crawford, Yumin Dai, Jeffrey Dove, Eric Fang, Yun Feng, Jean-Michel Florent, John Fuller, Alvar D Gossert, Mohammad Hekmat-Nejad, Chrystèle Henry, Julia Klopp, William P Lenahan, Andreas Lingel, Sylvia Ma, Arndt Meyer, Yuji Mishina, Jamie Narberes, Gwynn Pardee, Savithri Ramurthy, Sebastien Rieffel, Darrin Stuart, Sharadha Subramanian, Laura Tandeske, Stephania Widger, Armin Widmer, Aurelie Winterhalter, Isabel Zaror, Stephen Hardy
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174706 (2017)
RAS mutations lead to a constitutively active oncogenic protein that signals through multiple effector pathways. In this chemical biology study, we describe a novel coupled biochemical assay that measures activation of the effector BRAF by prenylated
Externí odkaz:
https://doaj.org/article/935bc8e9e098406ea024047d133a1803
Autor:
Isabel Zaror, Kenneth Crawford, Mohammad Hekmat-Nejad, Stephania Widger, Janet Sim, Hanne Merritt, Kelly Yan, Gwynn Pardee, Jan Marie Cheng
Publikováno v:
Protein Expression and Purification. 110:172-179
Extracellular signal-regulated kinase 2 (ERK2) is a serine/threonine protein kinase involved in many cellular programs, such as cell proliferation, differentiation, motility and programed cell-death. It is therefore considered an important target in
Autor:
Aurélie Winterhalter, Sharadha Subramanian, Tiffany Tsang, Jean-Michel Florent, Stephen F. Hardy, Laura Tandeske, Armin Widmer, Arndt Meyer, Johanna M. Jansen, Charles Wartchow, S. Rieffel, Stephania Widger, Yumin Dai, Tatiana Zavorotinskaya, Savithri Ramurthy, Dove Jeffrey H, Yun Feng, Julia Klopp, Isabel Zaror, Kenneth Crawford, Alvar D. Gossert, Susan Fong, Darrin Stuart, Yuji Mishina, John Fuller, Gwynn Pardee, Andreas Lingel, Lenahan William P, Keith B. Pfister, Mohammad Hekmat-Nejad, Jamie Narberes, Eric Fang, Dirksen E. Bussiere, Sylvia Ma, Wolfgang Jahnke, Jan Marie Cheng, Chrystèle Henry
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174706 (2017)
PLoS ONE, 12 (4)
PLoS ONE
PLoS ONE, 12 (4)
PLoS ONE
RAS mutations lead to a constitutively active oncogenic protein that signals through multiple effector pathways. In this chemical biology study, we describe a novel coupled biochemical assay that measures activation of the effector BRAF by prenylated
Publikováno v:
Journal of Parasitology. 95:1177-1182
Plagioporus kolipinskii n. sp. (Trematoda: Opecoelidae) is described from the intestine of the threespine stickleback, Gasterosteus aculeatus L., from Lobos Creek, a freshwater stream in Presidio, San Francisco County, California. Plagioporus kolipin
Autor:
Michel Faure, Darrin Stuart, Mohammad Hekmat-Nejad, Karen Yu, Ken Crawford, Yumin Dai, Tatiana Zavorotinskaya, Upasana Mehra, Kelly Yan, Xiaolei Ma, Jan Xuan, Charles Voliva, Jan Marie Cheng, Hanne Merritt
Publikováno v:
Cancer Research. 74:LB-121
The MAPK signaling cascade, comprised of the RAS GTPases, the RAF, MEK1/2 and ERK1/2 kinases is frequently deregulated in cancer. ERK1 and ERK2 transmit signals generated by mutant BRAF, Ras or by activated receptor tyrosine kinases to a wide range o