Výsledky vyhledávání - "Jan M. Tromp"

Akademický článek

Autor: Selina T.M. Monn, Jan M. Tromp, Stefan Schürch

Publikováno v: CHIMIA, Vol 59, Iss 11 (2005)

Within the past decade mass spectrometry has undoubtedly consolidated its role as a major player in modern bioanalysis. Mass spectrometry of oligonucleotides is an evolving field that has not reached its culmination point yet, as many aspects of olig

Externí odkaz: https://doaj.org/article/92a9aeb534d648f98e68673f54150973

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Electrospray ionization tandem mass spectrometry of biphenyl-modified oligo(deoxy)ribonucleotides

Autor: Stefan Schürch, Jan M. Tromp

Publikováno v: Rapid Communications in Mass Spectrometry. 20:2348-2354

Antisense oligonucleotides and aptamers are important candidates for future therapeutic applications. Different structural modifications are introduced into oligonucleotides to obtain high affinity and binding specificity. Sequence elucidation of oli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d217c49cfedb2b41bad50d684f2e72a7
https://doi.org/10.1002/rcm.2596

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Furan-oxidation-triggered inducible DNA cross-linking: acyclic versus cyclic furan-containing building blocks--on the benefit of restoring the cyclic sugar backbone

Autor: Sara Figaroli, Veronique Van Speybroeck, Stefan Schürch, Annemieke Madder, Michal Hocek, Kristof Stevens, Saron Catak, Jan M. Tromp, Diederica D. Claeys

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany). 17(25)

Oligodeoxynucleotides incorporating a reactive functionality can cause irreversible cross-linking to the target sequence and have been widely studied for their potential in inhibition of gene expression or development of diagnostic probes for gene an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8dfd71d25ea9faf4570c23f11046477
https://pubmed.ncbi.nlm.nih.gov/21598324

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CSTX-13, a highly synergistically acting two-chain neurotoxic enhancer in the venom of the spider Cupiennius salei (Ctenidae)

Autor: Stefan Schürch, Johann Schaller, Lucia Kuhn-Nentwig, Wolfgang Nentwig, Benno Wullschleger, Jan M. Tromp, Urs Kämpfer

The survival of the spiderCupiennius saleidepends on its hunting success, which largely relies on its immediately paralyzing multicomponent venom. Here, we report on the isolation and characterization of CSTX-13, a neurotoxic enhancer in the spider v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00a343bda8f99d943a2631ed36f5b99
https://europepmc.org/articles/PMC509190/

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