Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Jan M. Skotheim"'
Autor:
Evgeny Zatulovskiy, Michael C. Lanz, Shuyuan Zhang, Frank McCarthy, Joshua E. Elias, Jan M. Skotheim
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Increasing cell size drives changes to the proteome, which affects cell physiology. As cell size increases, some proteins become more concentrated while others are diluted. As a result, the state of the cell changes continuously with increasing size.
Externí odkaz:
https://doaj.org/article/1e1f1d973fe44e06a78a98a00e83a3e0
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Every type of cell in an animal maintains a specific size, which likely contributes to its ability to perform its physiological functions. While some cell size control mechanisms are beginning to be elucidated through studies of cultured cells, it is
Externí odkaz:
https://doaj.org/article/df5eae899ac34b3da43f5459d3584c64
Autor:
Alex Doan, Julia Arand, Diana Gong, Alexandros P. Drainas, Yan Ting Shue, Myung Chang Lee, Shuyuan Zhang, David M. Walter, Andrea C. Chaikovsky, David M. Feldser, Hannes Vogel, Lukas E. Dow, Jan M. Skotheim, Julien Sage
Publikováno v:
PLoS Genetics, Vol 17, Iss 12 (2021)
The retinoblastoma (RB) tumor suppressor is functionally inactivated in a wide range of human tumors where this inactivation promotes tumorigenesis in part by allowing uncontrolled proliferation. RB has been extensively studied, but its mechanisms of
Externí odkaz:
https://doaj.org/article/c1de44c222424f55b2ca3406c6f3a587
Autor:
Lichao Zhang, Sebastian Winkler, Fabian P. Schlottmann, Oliver Kohlbacher, Josh E. Elias, Jan M. Skotheim, Jennifer C. Ewald
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
The coordination of metabolism and growth with cell division is crucial for proliferation. While it has long been known that cell metabolism regulates the cell division cycle, it is becoming increasingly clear that the cell division cycle also regula
Externí odkaz:
https://doaj.org/article/fd6600d701c64a719785dac11d48a424
Publikováno v:
Annual Review of Cell and Developmental Biology. 38:291-319
The most fundamental feature of cellular form is size, which sets the scale of all cell biological processes. Growth, form, and function are all necessarily linked in cell biology, but we often do not understand the underlying molecular mechanisms no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b393aa8d5ff0f630796c2634f17c9831
https://doi.org/10.1146/annurev-cellbio-120219-040142
https://doi.org/10.1146/annurev-cellbio-120219-040142
Publikováno v:
Science. 374:347-351
Control by RNA polymerase II Evidence indicates that yeast cells initiate DNA synthesis and transition from the G 1 to the S phase of the cell cycle when cyclin 3 accumulates and causes phosphorylation of Whi5, a functional equivalent of the mammalia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3987804cdc24f5e92dcd75fc9f25a05
https://doi.org/10.1126/science.aba5186
https://doi.org/10.1126/science.aba5186
Accurate measurements of the molecular composition of single cells will be key to elucidating the relationship between gene expression and function in diverse cell types. One of the most important phenotypes that differs between cells is their size,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eabdf14a8f988317a72d71ac26294554
https://doi.org/10.1101/2022.10.17.512548
https://doi.org/10.1101/2022.10.17.512548
Publikováno v:
eLife. 11
Cell size is controlled to be within a specific range to support physiological function. To control their size, cells use diverse mechanisms ranging from ‘sizers’, in which differences in cell size are compensated for in a single cell division cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44499d3f4cd9ced8863e47e2a400c730
https://pubmed.ncbi.nlm.nih.gov/36178345
https://pubmed.ncbi.nlm.nih.gov/36178345
Autor:
Kurt M. Schmoller, Michael C. Lanz, Jacob Kim, Mardo Koivomagi, Yimiao Qu, Chao Tang, Igor V. Kukhtevich, Robert Schneider, Fabian Rudolf, David F. Moreno, Martí Aldea, Rafael Lucena, Jan M. Skotheim
Publikováno v:
Molecular Biology of the Cell, 33 (5)
Mol. Biol. Cell 33:lt1 (2022)
Mol. Biol. Cell 33:lt1 (2022)
Molecular Biology of the Cell, 33 (5)
ISSN:1939-4586
ISSN:1059-1524
ISSN:1939-4586
ISSN:1059-1524
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e097c0ff62ce8506f31c0f03f9307687
https://doi.org/10.1091/mbc.e21-01-0029
https://doi.org/10.1091/mbc.e21-01-0029