Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jan M. Schuller"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The challenge of endergonic reduction of NADP+ using NADH is overcome by ferredoxin-dependent transhydrogenases that employ electron bifurcation for electron carrier adjustments in the ancient Wood-Ljungdahl pathway. Recently, an electron-bi
Externí odkaz:
https://doaj.org/article/ea538622c2ea4097b9edd92e9759fed2
Autor:
Jan M. Schuller, Patricia Saura, Jacqueline Thiemann, Sandra K. Schuller, Ana P. Gamiz-Hernandez, Genji Kurisu, Marc M. Nowaczyk, Ville R. I. Kaila
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Cyanobacteria evolved carbon-concentration mechanisms to enhance the efficiency of photosynthetic CO2 fixation, but the molecular principles have remained unknown. Here authors use cryo-EM to reveal how modular adaptations enabled the photosynthetic
Externí odkaz:
https://doaj.org/article/fdb35269f4324350bc1d39dd44315e85
Publikováno v:
Biomolecules, Vol 4, Iss 3, Pp 774-794 (2014)
Emerging Mechanistic Insights into AAA Complexes Regulating Proteasomal Degradation
Externí odkaz:
https://doaj.org/article/36bfd0c4670e48468017fbe5d93d3e68
Autor:
Kanwal Kayastha, Alexander Katsyv, Christina Himmrich, Sonja Welsch, Jan M Schuller, Ulrich Ermler, Volker Müller
Publikováno v:
eLife, Vol 11 (2022)
Lactate oxidation with NAD+ as electron acceptor is a highly endergonic reaction. Some anaerobic bacteria overcome the energetic hurdle by flavin-based electron bifurcation/confurcation (FBEB/FBEC) using a lactate dehydrogenase (Ldh) in concert with
Externí odkaz:
https://doaj.org/article/e81572dee7df4488a0400afc5d9a5796
Autor:
Sandra K Schuller, Jan M Schuller, J Rajan Prabu, Marc Baumgärtner, Fabien Bonneau, Jérôme Basquin, Elena Conti
Publikováno v:
eLife, Vol 9 (2020)
The yeast THO complex is recruited to active genes and interacts with the RNA-dependent ATPase Sub2 to facilitate the formation of mature export-competent messenger ribonucleoprotein particles and to prevent the co-transcriptional formation of RNA:DN
Externí odkaz:
https://doaj.org/article/ca5bca414bd54d539d20e33850e76224
Autor:
Helge M. Dietrich, Ricardo D. Righetto, Anuj Kumar, Wojciech Wietrzynski, Raphael Trischler, Sandra K. Schuller, Jonathan Wagner, Fabian M. Schwarz, Benjamin D. Engel, Volker Müller, Jan M. Schuller
Publikováno v:
Nature. 607:823-830
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12d3e4eb62fb554028e052291df98c6c
https://doi.org/10.1038/s41586-022-04971-z
https://doi.org/10.1038/s41586-022-04971-z
Autor:
Alexander Katsyv, Anuj Kumar, Patricia Saura, Maximilian C. Pöverlein, Sven A. Freibert, Sven T. Stripp, Surbhi Jain, Ana P. Gamiz-Hernandez, Ville R. I. Kaila, Volker Müller, Jan M. Schuller
Electron bifurcation is a fundamental energy coupling mechanism widespread in microorganisms that thrive under anoxic conditions. These organisms employ hydrogen to reduce CO2, but the molecular mechanisms have remained enigmatic. The key enzyme resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f409d29160af4de5a2fa45b4724553
https://doi.org/10.17169/refubium-38641
https://doi.org/10.17169/refubium-38641
Autor:
Piotr Gerlach, Jan M Schuller, Fabien Bonneau, Jérôme Basquin, Peter Reichelt, Sebastian Falk, Elena Conti
Publikováno v:
eLife, Vol 7 (2018)
The nuclear RNA exosome complex mediates the processing of structured RNAs and the decay of aberrant non-coding RNAs, an important function particularly in human cells. Most mechanistic studies to date have focused on the yeast system. Here, we recon
Externí odkaz:
https://doaj.org/article/0f06029522794a4190ba3dbf02209ea7
Autor:
Mahesh Lingaraju, Fabien Bonneau, Elisabeth Weyher, Yair Gat, Elena Conti, Jan M. Schuller, Michael A. Strauss, Peter J. Murray
Publikováno v:
Nature Structural & Molecular Biology. 26:1089-1093
We report the 3.45-A resolution cryo-EM structure of human SMG1-SMG8-SMG9, a phosphatidylinositol-3-kinase (PI(3)K)-related protein kinase (PIKK) complex central to messenger RNA surveillance. Structural and MS analyses reveal the presence of inosito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7883b048cdd60a9bdbce10be6a360b8e
https://doi.org/10.1038/s41594-019-0342-7
https://doi.org/10.1038/s41594-019-0342-7