Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Jan M. Schilling"'
Autor:
Beatrice A. Golomb, Roel Sanchez Baez, Jan M. Schilling, Mehul Dhanani, McKenzie J. Fannon, Brinton K. Berg, Bruce J. Miller, Pam R. Taub, Hemal H. Patel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Gulf War illness (GWI) is an important exemplar of environmentally-triggered chronic multisymptom illness, and a potential model for accelerated aging. Inflammation is the main hypothesized mechanism for GWI, with mitochondrial impairment al
Externí odkaz:
https://doaj.org/article/c96f6dc30f414d43a2648e2e3b97e337
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Chronic pain is not a singular disorder and presents in various forms and phenotypes. Here we show data from a cohort of patients seeking treatment in a transdisciplinary pain clinic. Patients completed a multidimensional patient-reported ba
Externí odkaz:
https://doaj.org/article/dece970902c6488d980b8a5c2992bdbc
Autor:
Gerburg K. Schwaerzer, Hema Kalyanaraman, Darren E. Casteel, Nancy D. Dalton, Yusu Gu, Seunghoe Lee, Shunhui Zhuang, Nisreen Wahwah, Jan M. Schilling, Hemal H. Patel, Qian Zhang, Ayako Makino, Dianna M. Milewicz, Kirk L. Peterson, Gerry R. Boss, Renate B. Pilz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Individuals carrying a gain-of-function mutation in PKG1 develop thoracic aortic aneurysms and dissections. Here Schwaerzer et al. show that mice carrying the same mutation recapitulate the human disease, and find that treatment with anti-oxidants in
Externí odkaz:
https://doaj.org/article/1bb1d770c1fc4afd9a8c4a6eaa023c6b
Autor:
Julia C. Wilmanns, Raghav Pandey, Olivia Hon, Anjana Chandran, Jan M. Schilling, Elvira Forte, Qizhu Wu, Gael Cagnone, Preeti Bais, Vivek Philip, David Coleman, Heidi Kocalis, Stuart K. Archer, James T. Pearson, Mirana Ramialison, Joerg Heineke, Hemal H. Patel, Nadia A. Rosenthal, Milena B. Furtado, Mauro W. Costa
Publikováno v:
Molecular Metabolism, Vol 20, Iss , Pp 102-114 (2019)
Objective: Congenital heart disease (CHD) is the most frequent birth defect worldwide. The number of adult patients with CHD, now referred to as ACHD, is increasing with improved surgical and treatment interventions. However the mechanisms whereby AC
Externí odkaz:
https://doaj.org/article/54e4286b7710480bb545986201e5fddc
Autor:
Nina C. Weber, Jan M. Schilling, Moritz V. Warmbrunn, Mehul Dhanani, Raphaela Kerindongo, Jamila Siamwala, Young Song, Alice E. Zemljic-Harpf, McKenzie J. Fannon, Markus W. Hollmann, Benedikt Preckel, David M. Roth, Hemal H. Patel
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2640 (2019)
The noble gas helium (He) induces cardioprotection in vivo through unknown molecular mechanisms. He can interact with and modify cellular membranes. Caveolae are cholesterol and sphingolipid-enriched invaginations of the plasma-membrane-containing ca
Externí odkaz:
https://doaj.org/article/97fd7c8db8cc480fb17044fe98ab8bcb
Autor:
Mehul Dhanani, So Yeon Kim, Kang Ho Kim, Brian P. Head, Jan M. Schilling, David M. Roth, Joseph Leem, Hemal H. Patel, Alice E. Zemljic-Harpf
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Cirrhotic cardiomyopathy is a clinical syndrome in patients with liver cirrhosis characterized by blunted cardiac contractile responses to stress and/or heart rate-corrected QT (QTc) interval prolongation. Caveolin-3 (Cav-3) plays a critical role in
Autor:
Teresa Pasqua, Wei Ying, Kechun Tang, Ennio Avolio, Jan M. Schilling, Matthew A. Liu, Hongqiang Cheng, Hong Gao, Jing Zhang, Sumana Mahata, Myung S. Ko, Gautam Bandyopadhyay, Soumita Das, David M. Roth, Debashis Sahoo, Nicholas J.G. Webster, Farah Sheikh, Gourisankar Ghosh, Hemal H. Patel, Pradipta Ghosh, Greet van den Bogaart, Sushil K. Mahata
Publikováno v:
Vascular Pharmacology. 146:107066
Autor:
Miroslav Backonja, Michelle Sexton, Chloe G Hughes, Jan M. Schilling, Tobias Moeller-Bertram, Mark S. Wallace
Publikováno v:
Journal of Pain Research
Jan M Schilling,1 Chloe G Hughes,1 Mark S Wallace,2 Michelle Sexton,2 Miroslav Backonja,1,3 Tobias Moeller-Bertram1 1Clinical Research, Vitamed Research, Palm Desert, CA, USA; 2Department of Anesthesiology, University of California San Diego, San Die
Autor:
Jesse Wackerbarth, Martin Marsala, Oleksandr Platoshyn, David M. Roth, Atsushi Sawada, Piyush M. Patel, Joseph Leem, Hemal H. Patel, Junji Egawa, Brian P. Head, Alice E. Zemljic-Harpf, Shanshan Wang, Minyu Jian, Jan M. Schilling
Publikováno v:
The FASEB Journal. 33:7545-7554
Interventions that preserve motor neurons or restore functional motor neuroplasticity may extend longevity in amyotrophic lateral sclerosis (ALS). Delivery of neurotrophins may potentially revive degenerating motor neurons, yet this approach is depen
Autor:
Nadia Rosenthal, Milena B. Furtado, Vivek M. Philip, Stuart K. Archer, Jan M. Schilling, Anjana Chandran, Raghav Pandey, Hemal H. Patel, Julia C. Wilmanns, Gael Cagnone, Qizhu Wu, James T. Pearson, Joerg Heineke, Olivia J Hon, Preeti Bais, Mauro W. Costa, Heidi Kocalis, Mirana Ramialison, Elvira Forte, David Coleman
Publikováno v:
Molecular Metabolism, Vol 20, Iss, Pp 102-114 (2019)
Molecular Metabolism
Molecular Metabolism
Objective Congenital heart disease (CHD) is the most frequent birth defect worldwide. The number of adult patients with CHD, now referred to as ACHD, is increasing with improved surgical and treatment interventions. However the mechanisms whereby ACH