Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jan M. Niehues"'
Autor:
Lara R. Heij, Xiuxiang Tan, Jakob N. Kather, Jan M. Niehues, Shivan Sivakumar, Nicole Heussen, Gregory van der Kroft, Steven W. M. Olde Damink, Sven Lang, Merel R. Aberle, Tom Luedde, Nadine T. Gaisa, Jan Bednarsch, Drolaiz H. W. Liu, Jack P. M. Cleutjens, Dominik P. Modest, Ulf P. Neumann, Georg J. Wiltberger
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 3, p 490 (2021)
B cells and tertiary lymphoid structures (TLS) are reported to be important in survival in cancer. Pancreatic Cancer (PDAC) is one of the most lethal cancer types, and currently, it is the seventh leading cause of cancer-related death worldwide. A be
Externí odkaz:
https://doaj.org/article/b55e6a6d3b4c4b51b57b99e445d08417
Autor:
Jan Bednarsch, Steven W.M. Olde Damink, Judith de Vos-Geelen, Merel R. Aberle, Jakob Nikolas Kather, Jan M. Niehues, Svetlana Kintsler, Marcel den Dulk, Liselot B.J. Valkenburg-van Iersel, Guangshan Hao, Xiuxiang Tan, Nadine T. Gaisa, Anjali A. Roeth, Jarne Koolen, Georg Wiltberger, Shivan Sivakumar, Marielle M.E. Coolsen, Sven Arke Lang, Lara R. Heij, Ulf P. Neumann
Publikováno v:
Oncogene
Oncogene 40(5), 899-908 (2020). doi:10.1038/s41388-020-01578-4
Oncogene 40(5), 899-908 (2020). doi:10.1038/s41388-020-01578-4
Oncogene : including Oncogene reviews 40(5), 899-908 (2021). doi:10.1038/s41388-020-01578-4
Published by Springer Nature, London
Published by Springer Nature, London
Autor:
Ulf P. Neumann, Sven Arke Lang, Lara R. Heij, Jan Bednarsch, Georg Wiltberger, Jack P.M. Cleutjens, Tom Luedde, Drolaiz H. W. Liu, Nadine T. Gaisa, Steven W.M. Olde Damink, Xiuxiang Tan, Shivan Sivakumar, Dominik Paul Modest, Merel R. Aberle, Gregory van der Kroft, Nicole Heussen, Jakob Nikolas Kather, Jan M. Niehues
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, 10(3):490. Multidisciplinary Digital Publishing Institute (MDPI)
Journal of Clinical Medicine, Vol 10, Iss 490, p 490 (2021)
Journal of Clinical Medicine 10(3), 490 (2021). doi:10.3390/jcm10030490 special issue: "Special Issue "Pancreatic Cancer: Challenges and Breakthroughs" / Special Issue Editor: Dr. Maria Del Pilar Acedo Nunez, Guest Editor"
Volume 10
Issue 3
Journal of Clinical Medicine, 10(3):490. Multidisciplinary Digital Publishing Institute (MDPI)
Journal of Clinical Medicine, Vol 10, Iss 490, p 490 (2021)
Journal of Clinical Medicine 10(3), 490 (2021). doi:10.3390/jcm10030490 special issue: "Special Issue "Pancreatic Cancer: Challenges and Breakthroughs" / Special Issue Editor: Dr. Maria Del Pilar Acedo Nunez, Guest Editor"
Volume 10
Issue 3
Journal of Clinical Medicine 10(3), 490 (2021). doi:10.3390/jcm10030490 special issue: "Special Issue "Pancreatic Cancer: Challenges and Breakthroughs" / Special Issue Editor: Dr. Maria Del Pilar Acedo Nunez, Guest Editor"
Published by MDPI, Bas
Published by MDPI, Bas
Autor:
Ulf P. Neumann, Xiuxiang Tan, Drolaiz H. W. Liu, Nadine T. Gaisa, Shivan Sivakumar, Jan Bednarsch, Georg Wiltberger, Tom Luedde, Steven W.M. Olde Damink, Sven Arke Lang, Merel R. Aberle, Lara R. Heij, Nicole Heussen, Jack P.M. Cleutjens, Gregory van der Kroft, Jakob Nikolas Kather, Jan M. Niehues, Dominik Paul Modest
BackgroundB cells and tertiary lymphoid structures (TLS) are reported to be important in the improvement of survival of cancer patients. These secondary lymphoid organs have been associated with the generation of an anti-tumor response. Pancreatic du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7f924c66b90b17f7f0a6474071c9b7f
https://doi.org/10.1101/2020.08.07.232322
https://doi.org/10.1101/2020.08.07.232322
Autor:
Peter Boor, Chiara Loeffler, Akash Patnaik, Heike I. Grabsch, Jefree J. Schulte, Piet A. van den Brandt, Kai A. J. Sommer, Alexander T. Pearson, Loes F. S. Kooreman, Lara R. Heij, Jakob Nikolas Kather, Amelie Echle, Nadina Ortiz-Brüchle, Jan M. Niehues, Andrew Srisuwananukorn, Hermann Brenner, Nicole A. Cipriani, Andrew M. Hanby, Peter Bankhead, Hannah Sophie Muti, Sara Kochanny, Valerie Speirs, Roman D. Buelow, Jeremias Krause, Michael Hoffmeister, Tom Luedde, Dirk Jäger, Christian Trautwein
Publikováno v:
Nature Cancer, 1(8), 789-799. Nature Publishing Group
Nat Cancer
Nature Cancer
Kather, J N, Heij, L R, Grabsch, H, Loeffler, C, Echle, A, Muti, H S, Krause, J, Niehues, J M, Sommer, K A J, Bankhead, P, Kooreman, L F S, Schulte, J J, Cipriani, N A, Buelow, R D, Boor, P, Ortiz-Bruchle, N, Hanby, A M, Speirs, V, Kochanny, S, Patnaik, A, Srisuwananukorn, A, Brenner, H, Hoffmeister, M, Brandt, P A V D, Jäger, D, Trautwein, C, Pearson, A T & Luedde, T 2020, ' Pan-cancer image-based detection of clinically actionable genetic alterations ', nature cancer, vol. 1, no. 8, pp. 789–799 . https://doi.org/10.1038/s43018-020-0087-6
Nat Cancer
Nature Cancer
Kather, J N, Heij, L R, Grabsch, H, Loeffler, C, Echle, A, Muti, H S, Krause, J, Niehues, J M, Sommer, K A J, Bankhead, P, Kooreman, L F S, Schulte, J J, Cipriani, N A, Buelow, R D, Boor, P, Ortiz-Bruchle, N, Hanby, A M, Speirs, V, Kochanny, S, Patnaik, A, Srisuwananukorn, A, Brenner, H, Hoffmeister, M, Brandt, P A V D, Jäger, D, Trautwein, C, Pearson, A T & Luedde, T 2020, ' Pan-cancer image-based detection of clinically actionable genetic alterations ', nature cancer, vol. 1, no. 8, pp. 789–799 . https://doi.org/10.1038/s43018-020-0087-6
Molecular alterations in cancer can cause phenotypic changes in tumor cells and their microenvironment. Routine histopathology tissue slides, which are ubiquitously available, can reflect such morphological changes. Here, we show that deep learning c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5844bb58820a02ee29033be9fcdc522b
https://cris.maastrichtuniversity.nl/en/publications/054bcab0-00a9-4667-b697-9fbf758dba2f
https://cris.maastrichtuniversity.nl/en/publications/054bcab0-00a9-4667-b697-9fbf758dba2f
Autor:
Heike I. Grabsch, Christian Trautwein, Piet A. van den Brandt, Kai A. J. Sommer, Peter Bankhead, Akash Patnaik, Lara R. Heij, Michael Hoffmeister, Tom Luedde, Dirk Jäger, Nadina Ortiz-Brüchle, Hermann Brenner, Andrew Srisuwananukorn, Hannah Sophie Muti, Jefree J. Schulte, Jakob Nikolas Kather, Jan M. Niehues, Jeremias Krause, Amelie Echle, Nicole A. Cipriani, Alexander T. Pearson, Loes F. S. Kooreman, Chiara Loeffler
Precision treatment of cancer relies on genetic alterations which are diagnosed by molecular biology assays.1 These tests can be a bottleneck in oncology workflows because of high turnaround time, tissue usage and costs.2 Here, we show that deep lear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d501b5ca551cd0b57a762bc971decfad
Autor:
Jakob Nikolas Kather, Jan M. Niehues, Shivan Sivakumar, Lara R. Heij, Ulf P. Neumann, Nadine T. Gaisa, Xiuxiang Tan, Georg Wiltberger
Publikováno v:
Annals of Oncology. 31:S183-S184