Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jan M. Middeke"'
Autor:
Desiree Kunadt, Sebastian Stasik, Klaus H. Metzeler, Christoph Röllig, Christoph Schliemann, Philipp A. Greif, Karsten Spiekermann, Maja Rothenberg-Thurley, Utz Krug, Jan Braess, Alwin Krämer, Andreas Hochhaus, Sebastian Scholl, Inken Hilgendorf, Tim H. Brümmendorf, Edgar Jost, Björn Steffen, Gesine Bug, Hermann Einsele, Dennis Görlich, Cristina Sauerland, Kerstin Schäfer-Eckart, Stefan W. Krause, Mathias Hänel, Maher Hanoun, Martin Kaufmann, Bernhard Wörmann, Michael Kramer, Katja Sockel, Katharina Egger-Heidrich, Tobias Herold, Gerhard Ehninger, Andreas Burchert, Uwe Platzbecker, Wolfgang E. Berdel, Carsten Müller-Tidow, Wolfgang Hiddemann, Hubert Serve, Matthias Stelljes, Claudia D. Baldus, Andreas Neubauer, Johannes Schetelig, Christian Thiede, Martin Bornhäuser, Jan M. Middeke, Friedrich Stölzel, the A. M. L. Cooperative Group (AMLCG), Study Alliance Leukemia (SAL)
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-15 (2022)
Abstract Background The role of allogeneic hematopoietic cell transplantation (alloHCT) in acute myeloid leukemia (AML) with mutated IDH1/2 has not been defined. Therefore, we analyzed a large cohort of 3234 AML patients in first complete remission (
Externí odkaz:
https://doaj.org/article/1665eacc6b1a46028a7f2723eae46d4a
Autor:
Sebastian Stasik, Michael Kramer, Sven Zukunft, Christoph Röllig, Claudia D. Baldus, Uwe Platzbecker, Hubert Serve, Carsten Müller-Tidow, Kerstin Schäfer-Eckart, Martin Kaufmann, Stefan Krause, Tim Sauer, Mathias Hänel, Andreas Neubauer, Gerhard Ehninger, Martin Bornhäuser, Johannes Schetelig, Jan M. Middeke, Christian Thiede
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
FLT3-ITD mutations are common druggable alterations in patients with acute myeloid leukemia (AML) and associated with poor prognosis. Beside typical ITD mutations, point mutations and deletions in the juxtamembrane domain (JMD) have been observed. Ho
Externí odkaz:
https://doaj.org/article/8d2575e8bbbb4219af1ab53e7aaa14e3
Secondary Immune Thrombocytopenia (ITP) Associated with ChAdOx1 Covid-19 Vaccination – A Case Report
Autor:
Martin Koch, Sybille Fuld, Jan M. Middeke, Julia Fantana, Simone von Bonin, Jan Beyer-Westendorf
Publikováno v:
TH Open, Vol 05, Iss 03, Pp e315-e318 (2021)
Novel mRNA and vector-based covid-19 vaccinations have shown high efficacy in preventing symptomatic COVID-19 infections. Compared with the number of performed vaccinations, rates of severe side effects seem low. Rare prothrombotic coagulation disord
Externí odkaz:
https://doaj.org/article/3804292503c346628f451b185d84ffc3
Autor:
Friedrich Stölzel, Tors Lüer, Steffen Löck, Stefani Parmentier, Friederike Kuithan, Michael Kramer, Nael S. Alakel, Katja Sockel, Franziska Taube, Jan M. Middeke, Johannes Schetelig, Christoph Röllig, Tobias Paulus, Jörg Kotzerke, Gerhard Ehninger, Martin Bornhäuser, Markus Schaich, Klaus Zoephel
Publikováno v:
Haematologica, Vol 105, Iss 6 (2020)
Extramedullary (EM) disease in patients with acute myeloid leukemia (AML) is a known phenomenon. Since the prevalence of EM AML has so far only been clinically determined on examination, we performed a prospective study in patients with AML. The aim
Externí odkaz:
https://doaj.org/article/5d4ebb602d894bf69e83fff1213f1bd8
Autor:
Sebastian Stasik, Jan M. Middeke, Michael Kramer, Christoph Röllig, Alwin Krämer, Sebastian Scholl, Andreas Hochhaus, Martina Crysandt, Tim H. Brümmendorf, Ralph Naumann, Björn Steffen, Volker Kunzmann, Hermann Einsele, Markus Schaich, Andreas Burchert, Andreas Neubauer, Kerstin Schäfer-Eckart, Christoph Schliemann, Stefan Krause, Regina Herbst, Mathias Hänel, Norbert Frickhofen, Richard Noppeney, Ulrich Kaiser, Claudia D. Baldus, Martin Kaufmann, Zdenek Rácil, Uwe Platzbecker, Wolfgang E. Berdel, Jiri Mayer, Hubert Serve, Carsten Müller-Tidow, Gerhard Ehninger, Martin Bornhäuser, Johannes Schetelig, Christian Thiede
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Externí odkaz:
https://doaj.org/article/e2fa4b15317d40b6a7bb59bab5d3761c
Autor:
Falk Heidenreich, Elke Rücker-Braun, Juliane S. Walz, Anne Eugster, Denise Kühn, Sevina Dietz, Annika Nelde, Antje Tunger, Rebekka Wehner, Cornelia S. Link, Jan M. Middeke, Friedrich Stölzel, Torsten Tonn, Stefan Stevanovic, Hans-Georg Rammensee, Ezio Bonifacio, Michael Bachmann, Matthias Zeis, Gerhard Ehninger, Martin Bornhäuser, Johannes Schetelig, Marc Schmitz
Publikováno v:
Haematologica, Vol 102, Iss 11 (2017)
Externí odkaz:
https://doaj.org/article/176e4e3303e44d22aec608b09d162794
Autor:
Johannes R. Schmidt, Elke Rücker-Braun, Katharina Heidrich, Malte von Bonin, Friedrich Stölzel, Christian Thiede, Jan M. Middeke, Gerhard Ehninger, Martin Bornhäuser, Johannes Schetelig, Kristin Schubert, Martin von Bergen, Falk Heidenreich
Publikováno v:
Proteomes, Vol 6, Iss 1, p 11 (2018)
Targeting of leukemic stem cells with specific immunotherapy would be an ideal approach for the treatment of myeloid malignancies, but suitable epitopes are unknown. The comparative proteome-level characterization of hematopoietic stem and progenitor
Externí odkaz:
https://doaj.org/article/662fe80c6a614314950397e14616f297
Autor:
Sebastian Stasik, Clara Burkhard-Meier, Michael Kramer, Jan M. Middeke, Uta Oelschlaegel, Katja Sockel, Gerhard Ehninger, Hubert Serve, Carsten Müller-Tidow, Claudia D. Baldus, Christoph Röllig, Martin Bornhäuser, Uwe Platzbecker, Christian Thiede
Publikováno v:
Blood Advances. 6:3294-3303
Monitoring of measurable residual disease (MRD) in patients with acute myeloid leukemia (AML) is predictive of disease recurrence and may identify patients who benefit from treatment intensification. Current MRD techniques rely on multicolor flow cyt
Autor:
Raphael Teipel, Frank Kroschinsky, Michael Kramer, Theresa Kretschmann, Katharina Egger-Heidrich, Thomas Krüger, Leo Ruhnke, Sylvia Herold, Sebastian Stasik, Katja Sockel, Jan M. Middeke, Karolin Trautmann-Grill, Martin Bornhäuser, Christian Thiede, Malte von Bonin
Publikováno v:
Blood advances. 6(6)
Inflammation plays an important role in chimeric antigen receptor (CAR) T-cell therapy, especially in the pathophysiology of cytokine-release syndrome (CRS) and immune effector cell–associated neurotoxicity syndrome (ICANS). Clonal hematopoiesis of
Autor:
Jan M, Middeke, Raphael, Teipel, Christoph, Röllig, Sebastian, Stasik, Armin, Zebisch, Heinz, Sill, Michael, Kramer, Sebastian, Scholl, Andreas, Hochhaus, Edgar, Jost, Tim H, Brümmendorf, Ralph, Naumann, Björn, Steffen, Hubert, Serve, Heidi, Altmann, Volker, Kunzmann, Hermann, Einsele, Stefani, Parmentier, Markus, Schaich, Andreas, Burchert, Andreas, Neubauer, Christoph, Schliemann, Wolfgang E, Berdel, Katja, Sockel, Friedrich, Stölzel, Uwe, Platzbecker, Gerhard, Ehninger, Martin, Bornhäuser, Johannes, Schetelig, Christian, Thiede
Publikováno v:
Leukemialymphoma. 62(6)
We performed a registry-based analysis of 311 AML patients treated with decitabine in a standard of care setting to assess response and survival data with a distinct focus on the impact of the