Transferrin Saturation/Hepcidin Ratio Discriminates TMPRSS6-Related Iron Refractory Iron Deficiency Anemia from Patients with Multi-Causal Iron Deficiency Anemia

Autor: Hilde van der Staaij, Albertine E. Donker, Dirk L. Bakkeren, Jan M. J. I. Salemans, Lisette A. A. Mignot-Evers, Marlies Y. Bongers, Jeanne P. Dieleman, Tessel E. Galesloot, Coby M. Laarakkers, Siem M. Klaver, Dorine W. Swinkels

Publikováno v: International Journal of Molecular Sciences, 23, 3
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1917
International Journal of Molecular Sciences, 23(3):1917. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, 23
International Journal of Molecular Sciences, Vol 23, Iss 1917, p 1917 (2022)

Pathogenic TMPRSS6 variants impairing matriptase-2 function result in inappropriately high hepcidin levels relative to body iron status, leading to iron refractory iron deficiency anemia (IRIDA). As diagnosing IRIDA can be challenging due to its geno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e5c04445cd203c0134bbfc3d34d0e5
https://hdl.handle.net/2066/248824