Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jan M. Ehrchen"'
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Uncontrolled inflammation is a leading cause of many clinically relevant diseases. Current therapeutic strategies focus mainly on immunosuppression rather than on the mechanisms of inflammatory resolution. Glucocorticoids (GCs) are still the most wid
Externí odkaz:
https://doaj.org/article/6d72e0057d904524aef9283a5ae6db36
Autor:
Sarah Mayer-Hain, Kathleen Gebhardt, Matthias Neufeld, Jan M. Ehrchen, Karen Molyneux, Jonathan Barratt, Eva Nattkemper, Dennis Gerloff, Johannes Roth, Thomas Vogl, Karin I. Pappelbaum, Cord Sunderkötter
Publikováno v:
The Journal of Immunology. 209:1048-1058
In IgA vasculitis (IgAV) perivascular deposition of IgA1 immune complexes (IgA-ICs) is traditionally considered the fundamental trigger for polymorphonuclear neutrophil (PMN)–mediated damage. We propose that IgA-IC deposition, although mandatory, i
Autor:
Jan M Ehrchen, Kirsten Roebrock, Dirk Foell, Nadine Nippe, Esther von Stebut, Johannes M Weiss, Niels-Arne Münck, Dorothee Viemann, Georg Varga, Carsten Müller-Tidow, Hans-Joachim Schuberth, Johannes Roth, Cord Sunderkötter
Publikováno v:
PLoS Pathogens, Vol 6, Iss 4, p e1000871 (2010)
Experimental leishmaniasis is an excellent model system for analyzing Th1/Th2 differentiation. Resistance to Leishmania (L.) major depends on the development of a L. major specific Th1 response, while Th2 differentiation results in susceptibility. Th
Externí odkaz:
https://doaj.org/article/6493a6742fe44136a6161639025b50cd
Autor:
Jan, Däbritz, Toni, Weinhage, Georg, Varga, Timo, Wirth, Jan M, Ehrchen, Katarzyna, Barczyk-Kahlert, Johannes, Roth, Tobias, Schwarz, Dirk, Foell
Publikováno v:
European journal of immunology. 46(8)
In patients with juvenile idiopathic arthritis (JIA), increased release of IFN-γ and GM-CSF in cells infiltrating synovial tissue can be a potent driver of monocyte activation. Given the fundamental role of monocyte activation in remodeling the earl