Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Jan M Williams"'
Autor:
Denise C Cornelius, Olivia K Travis, Robert W Tramel, Marivee Borges-Rodriguez, Cedar H Baik, Mallory Greer, Chelsea A Giachelli, Geilda A Tardo, Jan M Williams
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234039 (2020)
Sepsis is characterized by organ dysfunction due to a dysregulated immune response to infection. Currently, no effective treatment for sepsis exists. Platelets are recognized as mediators of the immune response and may be a potential therapeutic targ
Externí odkaz:
https://doaj.org/article/586ca57a4c8b43a3acfdc9d6a68b23b1
Autor:
Fan Fan, Cheng-Wen Sun, Kristopher G Maier, Jan M Williams, Malikarjuna R Pabbidi, Sean P Didion, John R Falck, Jialong Zhuo, Richard J Roman
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82482 (2013)
The present study examined whether 20-hydroxyeicosatetraenoic acid (HETE) contributes to the vasoconstrictor effect of angiotensin II (ANG II) in renal microvessels by preventing activation of the large conductance Ca(2+)-activated K(+) channel (KCa)
Externí odkaz:
https://doaj.org/article/6632f31c961c4c898659b73d9389f703
Autor:
Corbin A. Shields, Geilda A. Tardo, Xi Wang, Gregory Peacock, Marcus Robbins, Hannah Glenn, Rachel Wilson, Jan M. Williams, Denise C. Cornelius
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 863 (2024)
Preeclampsia (PE) is characterized by maternal hypertension, fetal growth restriction (FGR), and increased inflammation and populations of cytotoxic NK cells (cNKs) and inflammatory T-Helper 17 cells (TH17s). Both cytotoxic NK cells and TH17 cells ar
Externí odkaz:
https://doaj.org/article/a27745e53d5f4cb1ba53735f9931e3fc
Autor:
Xi Wang, Olivia K. Travis, Corbin A. Shields, G. Ann Tardo, Chelsea Giachelli, Christopher W. Nutter, Hannah L. Glenn, Olive G. Cooper, Tatiana Davis, Rashauna Thomas, Jan M. Williams, Denise C. Cornelius
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 324:R556-R567
Preeclampsia (PE) is a pregnancy-specific hypertensive disorder with end-organ damage that presents after 20 wk of gestation. PE pathophysiology often includes vascular dysfunction and increased inflammation that continues to damage patient health ev
Autor:
Bibek Poudel, Ubong S. Ekperikpe, Sautan Mandal, Gregory E. Wilson, Corbin A. Shields, Denise C. Cornelius, Jan M. Williams
Publikováno v:
American Journal of Physiology-Renal Physiology.
Recently, we reported that the early progression of proteinuria in the obese Dahl salt-sensitive leptin receptor mutant (SSLepRmutant) strain was associated with increased renal macrophage infiltration prior to puberty. Macrophages can be divided int
Autor:
Jan M. Williams, Andrea K Brown, Geilda A. Tardo, Tyler Johnson, Chelsea Giachelli, Denise C. Cornelius, Madison T. Crosby, Olivia K. Travis, Shani Siddiq, Henry T. Nguyen
Publikováno v:
Pregnancy Hypertens
We recently reported that adoptive transfer of cytolytic Natural Killer cells (cNKs) from the Reduced Uterine Perfusion Pressure (RUPP) rat induces a preeclampsia (PE)-like phenotype in pregnant rats, accompanied by increased TNF-α. The purpose of t
Publikováno v:
Hypertension. 79
Preeclampsia (PE), a leading cause of maternal and fetal morbidity and mortality, is a hypertensive pregnancy disorder with end-organ damage that develops after 20 weeks of gestation. PE is characterized by chronic immune activation, endothelial dysf
Autor:
Evangeline M Deer, Jan M Williams, Lorena Amaral, Sarah Fitzgerald, Owen Herrock, Nathan Campbell, Babbette B Lamarca
Publikováno v:
Hypertension. 79
Hypertensive (HTN) disorders complicate ~10% of all pregnancies worldwide and contribute to maternal and fetal morbidity and mortality. HTN increases risks for preeclampsia and preterm labor in women with gestational diabetes mellitus (GDM) and is ch
Autor:
Xi Wang, Corbin A Shields, Ubong Ekperikpe, Lorena M Amaral, Jan M Williams, Denise C Cornelius
Publikováno v:
Current Opinion in Physiology. 33:100655
Publikováno v:
GeroScience
Diabetes, hypertension, and aging are major contributors to cardiovascular and chronic kidney disease (CKD). Sodium/glucose cotransporter 2 (SGLT2) inhibitors have become a preferred treatment for type II diabetic patients since they have cardiorenal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40f69d36470cfc78eae80ef8a8fe1e9
https://europepmc.org/articles/PMC9768063/
https://europepmc.org/articles/PMC9768063/