Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Jan Lankelma"'
Publikováno v:
BioTechniques, Vol 33, Iss 1, Pp 108-117 (2002)
Nylon membrane-based macroarrays form a widely available alternative to microarrays for the collection of large-scale gene expression data. To carry out repetitive hybridization experiments with nylon cDNA arrays, we used phosphorothioate 33P-cDNA, f
Externí odkaz:
https://doaj.org/article/b9053384e3864d1e8e87c1c9bdb2853b
Autor:
Jan Lankelma, Cyriel M. A. Pennartz, Jadin C. Jackson, Laura A. Van Mourik-Donga, Marian Joëls, Silviu I. Rusu
Publikováno v:
Behavioural Pharmacology, 29(4), 351-364. Lippincott Williams & Wilkins
Cognitive challenges are often accompanied by a discharge of stress hormones, which in turn modulate multiple brain areas. Among these, the medial temporal lobe and the prefrontal cortex are critically involved in high-order cognitive functions such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d941eb82aae59035d38183622339be
https://doi.org/10.1097/fbp.0000000000000370
https://doi.org/10.1097/fbp.0000000000000370
Publikováno v:
Lankelma, J, van Iperen, D J & van der Sluis, P J 2021, ' Towards using high-performance liquid chromatography at home ', Journal of Chromatography A, vol. 1639, 461925, pp. 1-11 . https://doi.org/10.1016/j.chroma.2021.461925
Journal of Chromatography A, 1639:461925, 1-11. Elsevier
Journal of Chromatography A, 1639:461925, 1-11. Elsevier
In order to make high-performance liquid chromatography (HPLC) more widely available at home and in small-scale settings, we have simplified two of its most costly modules, namely the pump and the detector. This should make the setup affordable for h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aad1927cc60d2489b17c2378d4d3e6c
https://doi.org/10.1016/j.chroma.2021.461925
https://doi.org/10.1016/j.chroma.2021.461925
Publikováno v:
Biosystems, 127, 1-6. Elsevier
BioSystems, 127, 1-6. Elsevier Ireland Ltd
Lankelma, J, Kooi, B W, Krab, K, Dorsman, J C, Joenje, H & Westerhoff, H V 2015, ' A reason for intermittent fasting to suppress the awakening of dormant breast tumors. ', BioSystems, vol. 127, pp. 1-6 . https://doi.org/10.1016/j.biosystems.2014.11.001
BioSystems, 127, 1-6. Elsevier Ireland Ltd
Lankelma, J, Kooi, B W, Krab, K, Dorsman, J C, Joenje, H & Westerhoff, H V 2015, ' A reason for intermittent fasting to suppress the awakening of dormant breast tumors. ', BioSystems, vol. 127, pp. 1-6 . https://doi.org/10.1016/j.biosystems.2014.11.001
For their growth, dormant tumors, which lack angiogenesis may critically depend on gradients of nutrients and oxygen from the nearest blood vessel. Because for oxygen depletion the distance from the nearest blood vessel to depletion will generally be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566e41a9c36b2cde52da05644f6297fc
https://dare.uva.nl/personal/pure/en/publications/a-reason-for-intermittent-fasting-to-suppress-the-awakening-of-dormant-breast-tumors(e8d5399d-2035-45c8-a399-7c04144fe633).html
https://dare.uva.nl/personal/pure/en/publications/a-reason-for-intermittent-fasting-to-suppress-the-awakening-of-dormant-breast-tumors(e8d5399d-2035-45c8-a399-7c04144fe633).html
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics, 40(4), 513-525. Springer New York
Lankelma, J, Fernandez Luque, R, Dekker, H, van den Berg, J & Kooi, B W 2013, ' A new mathematical pharmacodynamic model of clonogenic cancer cell death by doxorubicin ', Journal of Pharmacokinetics and Pharmacodynamics, vol. 40, no. 4, pp. 513-525 . https://doi.org/10.1007/s10928-013-9326-0
Lankelma, J, Fernandez Luque, R, Dekker, H, van den Berg, J & Kooi, B W 2013, ' A new mathematical pharmacodynamic model of clonogenic cancer cell death by doxorubicin ', Journal of Pharmacokinetics and Pharmacodynamics, vol. 40, no. 4, pp. 513-525 . https://doi.org/10.1007/s10928-013-9326-0
Previous models for predicting tumor cell growth are mostly based on measurements of total cell numbers. The purpose of this paper is to provide a new simple mathematical model for calculating tumor cell growth focusing on the fraction of cells that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62102b0d259166bd399695ebc37aa2de
https://research.vu.nl/en/publications/46ae4ebb-264f-4e3b-89f8-6e57f5e37dfd
https://research.vu.nl/en/publications/46ae4ebb-264f-4e3b-89f8-6e57f5e37dfd
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Lankelma, J, Nie, Z, Carrilho, E & Whitesides, G M 2012, ' Paper-based analytical device for electrochemical flow-injection analysis of glucose in urine. ', Analytical Chemistry, vol. 84, pp. 4147-4152 . https://doi.org/10.1021/ac3003648
Analytical Chemistry, 84, 4147-4152. American Chemical Society
Universidade de São Paulo (USP)
instacron:USP
Lankelma, J, Nie, Z, Carrilho, E & Whitesides, G M 2012, ' Paper-based analytical device for electrochemical flow-injection analysis of glucose in urine. ', Analytical Chemistry, vol. 84, pp. 4147-4152 . https://doi.org/10.1021/ac3003648
Analytical Chemistry, 84, 4147-4152. American Chemical Society
This article describes a new design for a paper-based electrochemical system for flow-injection analysis. Capillary wicking facilitates a gravity-driven flow of buffer solution continuously through paper and nitrocellulose, from a buffer reservoir at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a9d74a68422eacd94d6e2b53f435f3
https://doi.org/10.1021/ac3003648
https://doi.org/10.1021/ac3003648
Publikováno v:
The Journal of Neuroscience, 28(34), 8590-8603. Society for Neuroscience
Although single-cell coding of reward-related information in the orbitofrontal cortex (OFC) has been characterized to some extent, much less is known about the coding properties of orbitofrontal ensembles. We examined population coding of reward magn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39658a3808263fb0e4e2c30c619f85a4
https://doi.org/10.1523/jneurosci.5549-07.2008
https://doi.org/10.1523/jneurosci.5549-07.2008
Publikováno v:
Journal of chromatography. A, 1157(1-2), 142-150. Elsevier
Huertas-Perez, J F, Heger, M, Dekker, H L, Krabbe, H, Lankelma, J & Ariese, F 2007, ' Simple, rapid, and sensitive liquid chromatography-fluorescence method for the quantification of tranexamic acid in blood ', Journal of Chromatography A, vol. 1157, no. 1-2, pp. 142-50 . https://doi.org/10.1016/j.chroma.2007.04.067
Journal of Chromatography A, 1157(1-2), 142-50. Elsevier
Huertas-Perez, J F, Heger, M, Dekker, H L, Krabbe, H, Lankelma, J & Ariese, F 2007, ' Simple, rapid, and sensitive liquid chromatography-fluorescence method for the quantification of tranexamic acid in blood ', Journal of Chromatography A, vol. 1157, no. 1-2, pp. 142-50 . https://doi.org/10.1016/j.chroma.2007.04.067
Journal of Chromatography A, 1157(1-2), 142-50. Elsevier
Tranexamic acid (TA) is a synthetic antifibrinolytic agent that is being considered as a candidate adjuvant drug for site-specific pharmaco-laser therapy of port wine stains. For drug utility studies, a high-performance liquid chromatography (HPLC)-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a114543d3cbc4b5d8f34659be749ba4e
https://hdl.handle.net/1871/31031
https://hdl.handle.net/1871/31031
Autor:
P.H.J. Peters, Jan Lankelma, Petra Langerak, Hans V. Westerhoff, Jorrit J. Hornberg, Everardus J.J. van Zoelen, Henk L. Dekker
Publikováno v:
Molecular Biotechnology, 34, 101-108
Hornberg, J J, Dekker, H, Peters, P H J, Langerak, P, Westerhoff, H V, Lankelma, J & Zoelen, E J J 2006, ' Epidermal growth factor receptor-induced activato protein 1 activity controls density-dependent growht inhibition in normal rat kidney fibroblasts. ', Molecular Biotechnology, vol. 34, pp. 101-108 . https://doi.org/10.1385/MB:34:2:101
Molecular Biotechnology, 34, 101-108. Humana Press
Molecular Biotechnology, 34, 2, pp. 101-108
Hornberg, J J, Dekker, H, Peters, P H J, Langerak, P, Westerhoff, H V, Lankelma, J & Zoelen, E J J 2006, ' Epidermal growth factor receptor-induced activato protein 1 activity controls density-dependent growht inhibition in normal rat kidney fibroblasts. ', Molecular Biotechnology, vol. 34, pp. 101-108 . https://doi.org/10.1385/MB:34:2:101
Molecular Biotechnology, 34, 101-108. Humana Press
Molecular Biotechnology, 34, 2, pp. 101-108
Density-dependent growth inhibition secures tissue homeostasis. Dysfunction of the mechanisms, which regulate this type of growth control is a major cause of neoplasia. In confluent normal rat kidney (NRK) fibroblasts, epidermal growth factor (EGF) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f9f2c1af191154260ac01a7584c1ce
https://research.vu.nl/en/publications/2069e45c-e7ec-4b5e-bf95-fc0a55dd3d93
https://research.vu.nl/en/publications/2069e45c-e7ec-4b5e-bf95-fc0a55dd3d93
Autor:
Rutger A. Middelburg, Richard R. de Haas, Alejandro Mohar, Ron M. Kerkhoven, Adolfo Fuentes-Alburo, Henk L. Dekker, Herbert M. Pinedo, Paula R. Pohlmann, Jan Lankelma
Publikováno v:
Clinical Cancer Research. 11:1863-1869
Purpose: In biopsies of patients with locally advanced breast cancer, we investigated the in vivo changes of the gene expression pattern induced by chemotherapy to find genes that are potentially responsible for the efficacy of the drug. Experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d064673355587becee5eb477decb531
https://doi.org/10.1158/1078-0432.ccr-04-1372
https://doi.org/10.1158/1078-0432.ccr-04-1372