Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Jan L. Ceuppens"'
Autor:
Anne-Charlotte Jonckheere, Sven F. Seys, Brecht Steelant, Tatjana Decaesteker, Kaat Dekoster, Jonathan Cremer, Ellen Dilissen, Dominique Schols, Yoichiro Iwakura, Greetje Vande Velde, Christine Breynaert, Rik Schrijvers, Jeroen Vanoirbeek, Jan L. Ceuppens, Lieven J. Dupont, Dominique M. A. Bullens
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/0ec3806632074fb880d27f00217ad2c1
Autor:
Anne-Charlotte Jonckheere, Sven F. Seys, Brecht Steelant, Tatjana Decaesteker, Kaat Dekoster, Jonathan Cremer, Ellen Dilissen, Dominique Schols, Yoichiro Iwakura, Greetje Vande Velde, Christine Breynaert, Rik Schrijvers, Jeroen Vanoirbeek, Jan L. Ceuppens, Lieven J. Dupont, Dominique M. A. Bullens
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
RationaleNon-allergic asthma is driven by multiple endotypes of which neutrophilic and pauci-granulocytic asthma have been best established. However, it is still puzzling what drives inflammation and airway hyperreactivity (AHR) in these patients and
Externí odkaz:
https://doaj.org/article/240856200be54795986be5ac99b2c9d3
Autor:
Brecht Creyns, Jonathan Cremer, Gert De Hertogh, Louis Boon, Marc Ferrante, Séverine Vermeire, Gert Van Assche, Jan L. Ceuppens, Christine Breynaert
Publikováno v:
Immunity, Inflammation and Disease, Vol 8, Iss 3, Pp 393-407 (2020)
Abstract Introduction Insight in the pathogenesis of intestinal fibrosis is an unmet medical need in inflammatory bowel diseases. Studies in murine models and human organ fibrosis point to a potential role of innate lymphoid cells (ILC) in chronic in
Externí odkaz:
https://doaj.org/article/5d6cdb7792ed41ffaf8b40ff3704f4f5
Autor:
Brecht Creyns, Inge Jacobs, Bram Verstockt, Jonathan Cremer, Vera Ballet, Roselien Vandecasteele, Tim Vanuytsel, Marc Ferrante, Séverine Vermeire, Gert Van Assche, Jan L. Ceuppens, Christine Breynaert
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Patients with Crohn disease (CD) and ulcerative colitis (UC) suffer from chronic relapsing intestinal inflammation. While many studies focused on adaptive immunity, less is known about the role of innate immune cells in these diseases. Innate lymphoi
Externí odkaz:
https://doaj.org/article/1fbaaa909c7142f699d64bb2437bacaf
Autor:
Anne-Charlotte Jonckheere, Brecht Steelant, Sven F. Seys, Jonathan Cremer, Ellen Dilissen, Louis Boon, Adrian Liston, Rik Schrijvers, Christine Breynaert, Jeroen A. J. Vanoirbeek, Jan L. Ceuppens, Dominique M. A. Bullens
Publikováno v:
The Journal of Immunology. 209:1595-1605
Regulatory T cells (Tregs) that express the transcription factor Foxp3 have a critical role in limiting inflammatory processes and tissue damage. Whether Tregs are functional in maintaining epithelial barriers and in control of tight junction express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252e1fca3e429c5370cead149acb6b8e
https://doi.org/10.4049/jimmunol.2200416
https://doi.org/10.4049/jimmunol.2200416
Autor:
Bram Verstockt, Clémentine Perrier, Gert De Hertogh, Jonathan Cremer, Brecht Creyns, Gert Van Assche, Marc Ferrante, Jan L. Ceuppens, Séverine Vermeire, Christine Breynaert
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background: Mucosal IL-13 Receptor alpha 2 (IL13RA2) mRNA expression is one of the best predictive markers for primary non-responsiveness to infliximab therapy in patients with inflammatory bowel disease (IBD). The objective of this study was to unde
Externí odkaz:
https://doaj.org/article/d9d49cafa599439a8d6fd6e6d6a1a949
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 7 (2018)
The worldwide prevalence of allergic diseases has drastically increased in the past decades. Recent studies underline the importance of microbial exposure for the development of a balanced immune system. Consequently, probiotic bacteria are emerging
Externí odkaz:
https://doaj.org/article/24331bef632a43daada03ffc34060add
Autor:
Christine Breynaert, Tom Dresselaers, Clémentine Perrier, Ingrid Arijs, Jonathan Cremer, Leentje Van Lommel, Kristel Van Steen, Marc Ferrante, Frans Schuit, Séverine Vermeire, Paul Rutgeerts, Uwe Himmelreich, Jan L Ceuppens, Karel Geboes, Gert Van Assche
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68876 (2013)
INTRODUCTION: Chronically relapsing inflammation, tissue remodeling and fibrosis are hallmarks of inflammatory bowel diseases. The aim of this study was to investigate changes in connective tissue in a chronic murine model resulting from repeated cyc
Externí odkaz:
https://doaj.org/article/320431136fd349cba405ca1f73028adb
Autor:
Isabel, Vogel, Ahmad, Kasran, Jonathan, Cremer, Yoo-Jin, Kim, Louis, Boon, Stefaan W, Van Gool, Jan L, Ceuppens
Publikováno v:
European journal of immunology. 45(6)
Naïve T cells require B7/CD28 costimulation in order to be fully activated. Attempts to block this pathway have been effective in preventing unwanted immune reactions. As B7 blockade might also affect Treg cells and interfere with negative signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a026773725373484ed732b5c03496386
https://pubmed.ncbi.nlm.nih.gov/25727069
https://pubmed.ncbi.nlm.nih.gov/25727069
Publikováno v:
European journal of immunology. 43(4)
Costimulatory signals are required for priming and activation of naive T cells, while it is less clear how they contribute to induction of regulatory T (Treg)-cell activity. We previously reported that the blockade of the B7-CD28 and CD40L-CD40 inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf2c49bcb57954bedfb53c3d75a72784
https://pubmed.ncbi.nlm.nih.gov/23348953
https://pubmed.ncbi.nlm.nih.gov/23348953