Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jan L Vinkenborg"'
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82009 (2013)
Magnesium has important structural, catalytic and signaling roles in cells, yet few tools exist to image this metal ion in real time and at subcellular resolution. Here we report the first genetically encoded sensor for Mg(2+), MagFRET-1. This sensor
Externí odkaz:
https://doaj.org/article/aaf52659d13f4a3b9e9670d105d0ff82
Autor:
Leo J. van IJzendoorn, Nuria Teigell Beneitez, Geert Van Steenberge, Ganeshram Krishnamoorthy, Jan L. Vinkenborg, Jean Schleipen, Jeroen Missinne, Gerard Rietjens, E.W.A. Visser, Menno Willem Jose Prins, Joke G Orsel, Marc A. Verschuuren
Publikováno v:
IEEE Journal of Selected Topics in Quantum Electronics, 22(3), 1-8. Institute of Electrical and Electronics Engineers
We present a polymer optical waveguide integration technology for the detection of nanoparticles in an evanescent field (EF)-based biosensor. Polymer waveguides together with their light coupling structures are designed to be integrated in a novel ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2641ce1af62c3e139560dfb252634e2
http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=7274344
http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=7274344
Autor:
Hong Ding, Hualiang Jiang, Shisheng Ouyang, Ruiting Lin, Jan L. Vinkenborg, Hong Liu, Yu Zhou, Jing Chen, Qiancheng You, Shijie Chen, Naixia Zhang, Yuxin Xie, Shannon Elf, Jason Karpus, Maarten Merkx, Hee-Bum Kang, Chi Hao Luan, Cheng Luo, Jun Fan, Junyan Lu, Yi Wen, Dali Han, Jing Wang, Changliang Shan, Chuan He
Publikováno v:
Nature Chemistry, 7. Nature Publishing Group
Copper is a transition metal that plays critical roles in many life processes. Controlling the cellular concentration and trafficking of copper offers a route to disrupt these processes. Here we report small molecules that inhibit the human copper-tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888e4ddeaa49a6fb6ac7a0eb5b469fd6
https://doi.org/10.1038/nchem.2381
https://doi.org/10.1038/nchem.2381
Publikováno v:
Angewandte Chemie. 124:9311-9315
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b45c6d408f0d4d29fce815fc341115ec
https://doi.org/10.1002/ange.201204174
https://doi.org/10.1002/ange.201204174
Publikováno v:
Chemical Communications, ChemComm, 47(43), 11879-11881. Royal Society of Chemistry
Introduction of a (Cys)(4) metal binding site at the dimerization interface of two fluorescent protein domains yields a chelating FRET sensor protein that shows a 2500-fold selectivity for Cd(2+) over Zn(2+) by taking advantage of their different ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd00d51118db1c5cad32a9684bd8cd4
https://doi.org/10.1039/c1cc14944j
https://doi.org/10.1039/c1cc14944j
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e82009 (2013)
PLoS ONE, 8(12), e82009-1/10. Public Library of Science
PLoS ONE, Vol 8, Iss 12, p e82009 (2013)
PLoS ONE, 8(12), e82009-1/10. Public Library of Science
Magnesium has important structural, catalytic and signaling roles in cells, yet few tools exist to image this metal ion in real time and at subcellular resolution. Here we report the first genetically encoded sensor for Mg(2+), MagFRET-1. This sensor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340d78153dc46ab67ea96c8d0aa2adcc
Autor:
Wolf B. Frommer, Guido Grossmann, Jan L. Vinkenborg, Sébastien Thomine, Maarten Merkx, Viviane Lanquar
Publikováno v:
New Phytologist, 202, 198-208. Wiley-Blackwell
Summary Zinc plays a central role in all living cells as a cofactor for enzymes and as a structural element enabling the adequate folding of proteins. In eukaryotic cells, metals are highly compartmentalized and chelated. Although essential to charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aaefde9373e73652f5de023b14dd074
https://pubmed.ncbi.nlm.nih.gov/24571692
https://pubmed.ncbi.nlm.nih.gov/24571692
Publikováno v:
Biochemical Society Transactions, 41(5), 1201-1205. Portland Press Ltd.
Biochemical Society Transactions
Biochemical Society Transactions
Proteins that switch between distinct conformational states are ideal to monitor and control molecular processes within the complexity of biological systems. Inspired by the modular architecture of natural signalling proteins, our group explores gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596c56d896d2c567661184308959bed1
https://research.tue.nl/nl/publications/354b2eec-d81f-49b2-81d0-f7ec39cca591
https://research.tue.nl/nl/publications/354b2eec-d81f-49b2-81d0-f7ec39cca591
Publikováno v:
Angewandte Chemie (International ed.in English)
A most able label: Labeled aptamers can be cross-linked to their target structures in a light-dependent and highly specific manner as a result of a new strategy termed aptamer-based affinity labeling (ABAL) of proteins. The aptamer-protein complexes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d199fcb256c45d6d257240d0930be5
https://pubmed.ncbi.nlm.nih.gov/22865679
https://pubmed.ncbi.nlm.nih.gov/22865679
Publikováno v:
ChemInform. 42
Switch protein switch! Proteins that switch between distinct conformational states are ideal for monitoring and controlling molecular processes in biological systems. We discuss new engineering concepts for the construction of protein switches that h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e186ed744354f1f6d54c61b93ba4f5f4
https://doi.org/10.1002/chin.201120260
https://doi.org/10.1002/chin.201120260