Zobrazeno 1 - 10
of 271
pro vyhledávání: '"Jan Kremers"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
PurposeElectroretinograms elicited by photopigment isolating white noise stimuli (wnERGs) in mice were measured. The dependency of rod- and cone-opsin-driven wnERGs on mean luminance was studied.MethodsTemporal white noise stimuli (containing all fre
Externí odkaz:
https://doaj.org/article/5dded5fc55ad45979fd2e824d79a5a4b
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Our past anecdotal evidence prompted that a longer response window (RW) in the Trivector test (Cambridge Colour Test) improved mature observers’ estimates of chromatic discrimination. Here, we systematically explored whether RW variation a
Externí odkaz:
https://doaj.org/article/3aa2474a1548485b872e4bee35617213
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
PurposeTo record and analyse electroretinograms (ERGs) to luminance stimuli with white noise temporal profiles in mice. White noise stimuli are expected to keep the retina in a physiologically more natural state than, e.g., flashes. The influence of
Externí odkaz:
https://doaj.org/article/7b8e159146f546e6928b9762b0a7c6e1
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Electroretinograms (ERGs) are mass potentials with a retinal origin that can be measured non-invasively. They can provide information about the physiology of the retina. Often, ERGs are measured to flashes that are highly unnatural stimuli. To obtain
Externí odkaz:
https://doaj.org/article/f08e2acbaac047f98ff3b3ec17d74c89
Autor:
Mirella Telles Salgueiro Barboni, André Maurício Passos Liber, Anneka Joachimsthaler, Amel Saoudi, Aurélie Goyenvalle, Alvaro Rendon, Jérome E. Roger, Dora Fix Ventura, Jan Kremers, Cyrille Vaillend
Publikováno v:
Neurobiology of Disease, Vol 152, Iss , Pp 105288- (2021)
The mdx52 mouse model of Duchenne muscular dystrophy (DMD) is lacking exon 52 of the DMD gene that is located in a hotspot mutation region causing cognitive deficits and retinal anomalies in DMD patients. This deletion leads to the loss of the dystro
Externí odkaz:
https://doaj.org/article/172457834efd45038fd22b1f72f68a27
Autor:
Uwe Thorsten Lux, Johanna Ehrenberg, Anneka Joachimsthaler, Jenny Atorf, Bianca Pircher, Kerstin Reim, Jan Kremers, Andreas Gießl, Johann Helmut Brandstätter
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8131 (2021)
Complexins (Cplxs) 1 to 4 are components of the presynaptic compartment of chemical synapses where they regulate important steps in synaptic vesicle exocytosis. In the retina, all four Cplxs are present, and while we know a lot about Cplxs 3 and 4, l
Externí odkaz:
https://doaj.org/article/a25ba281dc764053926a1335d8e52bcc
Autor:
Stefan Kurtenbach, Andreas Gießl, Siv Strömberg, Jan Kremers, Jenny Atorf, Sebastian Rasche, Eva M. Neuhaus, Denis Hervé, Johann Helmut Brandstätter, Esther Asan, Hanns Hatt, Manfred W. Kilimann
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-19 (2017)
Abstract BEACH domain proteins are involved in membrane protein traffic and human diseases, but their molecular mechanisms are not understood. The BEACH protein LRBA has been implicated in immune response and cell proliferation, and human LRBA mutati
Externí odkaz:
https://doaj.org/article/3f19e8543c154b8eb7ffd756b3258257
Autor:
Kaspar Gierke, Julia von Wittgenstein, Maike Hemmerlein, Jenny Atorf, Anneka Joachimsthaler, Jan Kremers, Benjamin H. Cooper, Frederique Varoqueaux, Hanna Regus-Leidig, Johann Helmut Brandstätter
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 7848 (2020)
Munc13 isoforms are constituents of the presynaptic compartment of chemical synapses, where they govern important steps in preparing synaptic vesicles for exocytosis. The role of Munc13-1, -2 and -3 is well documented in brain neurons, but less is kn
Externí odkaz:
https://doaj.org/article/a57bd6d9373e44c6929b6d46057a036b
Autor:
Nathalie Falk, Anneka Joachimsthaler, Kristin Kessler, Uwe Thorsten Lux, Angelika Anna Noegel, Jan Kremers, Johann Helmut Brandstätter, Andreas Gießl
Publikováno v:
Cells, Vol 8, Iss 10, p 1238 (2019)
Syne-2 (also known as Nesprin-2) is a member of a family of proteins that are found primarily in the outer nuclear membrane, as well as other subcellular compartments. Syne-2 contains a C-terminal KASH transmembrane domain and is part of a protein ne
Externí odkaz:
https://doaj.org/article/cbc97f4932f345869b0b435aae050f61
Autor:
Aline Correa de Carvalho, Martin Schwarz, Givago da Silva Souza, Bruno Duarte Gomes, Alexandre Antônio Marques Rosa, Ana Maria Revoredo da Silva Ventura, José Maria de Souza, Luiz Carlos de Lima Silveira, Jan Kremers
Publikováno v:
Journal of Ophthalmic & Vision Research, Vol 8, Iss 3, Pp 193-198 (2013)
Purpose: To investigate changes in multifocal electroretinography (mfERG) parameters associated with high dose chloroquine therapy for treatment of malaria in the Amazonia region of Brazil. Methods: Forty-eight subjects who had received chloroquine t
Externí odkaz:
https://doaj.org/article/109c7cfdc8154885ba1705aa861d33c0