Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jan Kosiński"'
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5122 (2019)
The floral development in an important legume crop yellow lupine (Lupinus luteus L., Taper cv.) is often affected by the abscission of flowers leading to significant economic losses. Small non-coding RNAs (sncRNAs), which have a proven effect on almo
Externí odkaz:
https://doaj.org/article/77135d9cdae74bae9c2210c3124dc97a
Autor:
Jan Kosiński, Marek Żywicki
SummaryThe recent development of high-throughput workflows in genomics and transcriptomics revealed that efficient annotation is essential for effective data processing and analysis. Although a variety of tools dedicated to this purpose is available,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2027e30f15633ed1e743c65f66f46903
https://doi.org/10.1101/2022.11.13.516331
https://doi.org/10.1101/2022.11.13.516331
Autor:
Tânia F. Custódio, Maxime Killer, Dingquan Yu, Virginia Puente, Daniel P. Teufel, Alexander Pautsch, Gisela Schnapp, Marc Grundl, Jan Kosinski, Christian Löw
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract PHT1 is a histidine /oligopeptide transporter with an essential role in Toll-like receptor innate immune responses. It can act as a receptor by recruiting the adaptor protein TASL which leads to type I interferon production via IRF5. Persist
Externí odkaz:
https://doaj.org/article/4be3f59ad2c440dca63059f50336a519
Autor:
Ewa Sitarska, Silvia Dias Almeida, Marianne Sandvold Beckwith, Julian Stopp, Jakub Czuchnowski, Marc Siggel, Rita Roessner, Aline Tschanz, Christer Ejsing, Yannick Schwab, Jan Kosinski, Michael Sixt, Anna Kreshuk, Anna Erzberger, Alba Diz-Muñoz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract To navigate through diverse tissues, migrating cells must balance persistent self-propelled motion with adaptive behaviors to circumvent obstacles. We identify a curvature-sensing mechanism underlying obstacle evasion in immune-like cells. S
Externí odkaz:
https://doaj.org/article/505ca1c735d5448bb63418ff9ca18075
Publikováno v:
SoftwareX, Vol 25, Iss , Pp 101636- (2024)
Cryogenic electron microscopy (cryo-EM) is a key method in structural and cell biology. Analysis of cryo-EM images requires interpretation of noisy, low-resolution densities, which relies on identifying the most probable orientation of macromolecules
Externí odkaz:
https://doaj.org/article/e7e73be7765043318cae0e89b15250d7
Autor:
Josie L. Ferreira, Vojtěch Pražák, Daven Vasishtan, Marc Siggel, Franziska Hentzschel, Annika M. Binder, Emma Pietsch, Jan Kosinski, Friedrich Frischknecht, Tim W. Gilberger, Kay Grünewald
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Microtubules are a ubiquitous eukaryotic cytoskeletal element typically consisting of 13 protofilaments arranged in a hollow cylinder. Using CryoEM and subvolume averaging, Ferreira and Pražák et al. show that Plasmodium does not adhere to a single
Externí odkaz:
https://doaj.org/article/1ec7f99f7ae54d35a6fecfd9f8a89cab
Autor:
Matthias K. Vorländer, Anna Jungblut, Kai Karius, Florence Baudin, Helga Grötsch, Jan Kosinski, Christoph W. Müller
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Transcription factor TFIIIC plays roles in Pol III transcription and in chromatin organization. CryoEM structure of the yeast TFIIIC subcomplex τA, a negative stain reconstruction of τA bound to the TFIIIB subunits Brf1 and TBP and accompanying bio
Externí odkaz:
https://doaj.org/article/0338fb67478441cfbefda6b1f35f56f9
Autor:
Shyamal Mosalaganti, Jan Kosinski, Sahradha Albert, Miroslava Schaffer, Daniela Strenkert, Patrice A. Salomé, Sabeeha S. Merchant, Jürgen M. Plitzko, Wolfgang Baumeister, Benjamin D. Engel, Martin Beck
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
While the architecture of vertebrate nuclear pore complexes (NPCs) is well understood, the extent of its evolutionary conservation is still unclear. Here, the authors analyze the in situ architecture of an algal NPC, revealing distinct structural fea
Externí odkaz:
https://doaj.org/article/d5b2c6bf446f4dc1bf1a94753ef03049
Autor:
Toby Mathieson, Holger Franken, Jan Kosinski, Nils Kurzawa, Nico Zinn, Gavain Sweetman, Daniel Poeckel, Vikram S. Ratnu, Maike Schramm, Isabelle Becher, Michael Steidel, Kyung-Min Noh, Giovanna Bergamini, Martin Beck, Marcus Bantscheff, Mikhail M. Savitski
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The proteome-wide characterization of proteostasis depends on robust approaches to determine protein half-lives. Here, the authors improve the accuracy and precision of mass spectrometry-based quantification, enabling reliable protein half-life deter
Externí odkaz:
https://doaj.org/article/da0726d0c6b44f4fa437f686bacfcd20
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
The Nup82–Nup159–Nsp1 complex, which plays a key role in mRNA export, is recruited late during the process of nuclear pore complex (NPC) assembly. Here the authors combine crosslinking mass spectrometry, biochemical reconstitution and molecular m
Externí odkaz:
https://doaj.org/article/78609ff12d0b48928339246d519bd94b