Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jan Kopf"'
Apoptotic Regulation by the Crk Adapter Protein Mediated by Interactions with Wee1 and Crm1/Exportin
Autor:
Jan Kopf, Sally Kornbluth, Minoru Yoshida, Jesse J. Smith, Robert E. Hollingsworth, D. Ashley Richardson
Publikováno v:
Molecular and Cellular Biology. 22:1412-1423
The adapter protein Crk contains an SH2 domain and two SH3 domains. Through binding of particular ligands to the SH2 domain and the N-terminal SH3 domain, Crk has been implicated in a number of signaling processes, including regulation of cell growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9676a754ae6c77960df835b368a82079
https://doi.org/10.1128/mcb.22.5.1412-1423.2002
https://doi.org/10.1128/mcb.22.5.1412-1423.2002
Publikováno v:
Molecular and General Genetics MGG. 227:318-329
The pathogenic yeast, Candida albicans, is insensitive to the anti-mitotic drug, benomyl, and to the dihydrofolate reductase inhibitor, methotrexate. Genes responsible for the intrinsic drug resistance were sought by transforming Saccharomyces cerevi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df84165ed0c7381994df48e06bce7931
https://doi.org/10.1007/bf00259685
https://doi.org/10.1007/bf00259685
Autor:
Patrick J. McMillen, Callum J. Bell, Nancy S. Shepherd, Linda P. Briley, Eric H. Lai, Jan Kopf, David Briley, Daniel K. Burns, Geoff Joslyn, Kirby Gottschalk, James L. Weber, Melanie Reisman, Maha Chabhar Karnoub, David Vaske, Donald C. Holt, Hakan Sakul, Quan Nguyen, Michael J. Wagner, Margaret G. Ehm
Publikováno v:
American journal of human genetics. 66(6)
Type 2 diabetes is a serious, genetically influenced disease for which no fully effective treatments are available. Identification of biochemical or regulatory pathways involved in the disease syndrome could lead to innovative therapeutic interventio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc40e28d8448a008076e45ace85df23
https://pubmed.ncbi.nlm.nih.gov/10793009
https://pubmed.ncbi.nlm.nih.gov/10793009
Publikováno v:
Nucleic acids research. 13(19)
The nucleotide sequence of a transposon Tn7 DNA fragment encoding a 3"(9)-O-nucleotidyltransferase, an aminoglycoside-modifying enzyme, which mediates bacterial resistance to spectinomycin and streptomycin, was determined. The aadA structural gene wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6405d32918cade4b70b660c77db4f12
https://pubmed.ncbi.nlm.nih.gov/2997737
https://pubmed.ncbi.nlm.nih.gov/2997737
Publikováno v:
Gene. 63(2)
The nucleotide sequence of a DNA fragment that contained the Saccharomyces cerevisiae gene DFR coding for dihydrofolate reductase (DHFR) was determined. The DHFR was encoded by a 633-bp open reading frame, which specified an Mr24264 protein. The poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead884d7047d84979372782de54c63b4
https://pubmed.ncbi.nlm.nih.gov/2838385
https://pubmed.ncbi.nlm.nih.gov/2838385
Publikováno v:
Plasmid. 19(1)
The plasmid pAZ1, which determines trimethoprim and sulfonamide resistance, was characterized by restriction endonuclease mapping. The restriction map was identical to that of the incQ plasmid RSF1010 over a 5.1-kbp region. The type III dihydrofolate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69857083af02b084924acb714022f655
https://pubmed.ncbi.nlm.nih.gov/2840679
https://pubmed.ncbi.nlm.nih.gov/2840679