Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Jan Kopecky"'
Autor:
Andrea Benova, Michaela Ferencakova, Kristina Bardova, Jiri Funda, Jan Prochazka, Frantisek Spoutil, Tomas Cajka, Martina Dzubanova, Tim Balcaen, Greet Kerckhofs, Wouter Willekens, G. Harry van Lenthe, Arzuv Charyyeva, Glenda Alquicer, Alena Pecinova, Tomas Mracek, Olga Horakova, Roman Coupeau, Morten Svarer Hansen, Martin Rossmeisl, Jan Kopecky, Michaela Tencerova
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Obesity adversely affects bone and fat metabolism in mice and humans. Omega-3 polyunsaturated fatty acids (omega-3 PUFAs) have been shown to improve glucose metabolism and bone homeostasis in obesity. However, the impact of omega-3 PUFAs on
Externí odkaz:
https://doaj.org/article/4561b44395d7415182b87647a147ec6e
Autor:
Catalina Picó, Empar Lurbe, Jaap Keijer, Jan Kopecky, Jean-François Landrier, Julio Álvarez-Pitti, Jean Charles Martin, Paula Oliver, Andreu Palou, Mariona Palou, Petr Zouhar, Joan Ribot, Ana M. Rodríguez, Juana Sánchez, Francisca Serra, M. Luisa Bonet
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
BackgroundPhysical activity (PA) provides health benefits across the lifespan and improves many established cardiovascular risk factors that have a significant impact on overall mortality. However, discrepancies between self-reported and device-based
Externí odkaz:
https://doaj.org/article/8f388a91f0f24b9cb44d681c1fbe141c
Autor:
Erik Ehinger, Jan Kopecky, Anna Darabi, Edward Visse, Charlotte Edvardsson, Gregor Tomasevic, David Cederberg, Mattias Belting, Johan Bengzon, Peter Siesjö
Publikováno v:
BMC Neurology, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Purpose Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Despite the best available treatment, prognosis remains poor. Current standard therapy consists of surgical removal of the tumor followed by radiotherapy
Externí odkaz:
https://doaj.org/article/11d4701526cb419e84a12c1692767331
Autor:
Olga Horakova, Gabriella Sistilli, Veronika Kalendova, Kristina Bardova, Marko Mitrovic, Tomas Cajka, Ilaria Irodenko, Petra Janovska, Karoline Lackner, Jan Kopecky, Martin Rossmeisl
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionNon-alcoholic fatty liver disease (NAFLD) can progress to more severe stages, such as steatohepatitis and fibrosis. Thermoneutral housing together with high-fat diet promoted NAFLD progression in C57BL/6J mice. Due to possible differences
Externí odkaz:
https://doaj.org/article/8f805a1becbe4000a52309d7f53c4d18
Autor:
Petra Janovska, Petr Zouhar, Kristina Bardova, Jakub Otahal, Marek Vrbacky, Tomas Mracek, Katerina Adamcova, Lucie Lenkova, Jiri Funda, Tomas Cajka, Zdenek Drahota, Sara Stanic, Arild C. Rustan, Olga Horakova, Josef Houstek, Martin Rossmeisl, Jan Kopecky
Publikováno v:
Molecular Metabolism, Vol 69, Iss , Pp 101683- (2023)
Objective: Non-shivering thermogenesis (NST) mediated by uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) can be activated via the adrenergic system in response to cold or diet, contributing to both thermal and energy homeostasis. Other mech
Externí odkaz:
https://doaj.org/article/31f0b59f9117425794b61598c518ae9c
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Glioblastoma has remained the deadliest primary brain tumor while its current therapy offers only modest survival prolongation. Immunotherapy has failed to record notable benefits in routine glioblastoma treatment. Conventionally, immunother
Externí odkaz:
https://doaj.org/article/925b2a31965349c29f03330b8a51108a
Autor:
Andrea Benova, Michaela Ferencakova, Kristina Bardova, Jiri Funda, Jan Prochazka, Frantisek Spoutil, Tomas Cajka, Martina Dzubanova, Tim Balcaen, Greet Kerckhofs, Wouter Willekens, G. Harry van Lenthe, Glenda Alquicer, Alena Pecinova, Tomas Mracek, Olga Horakova, Martin Rossmeisl, Jan Kopecky, Michaela Tencerova
Publikováno v:
Molecular Metabolism, Vol 65, Iss , Pp 101598- (2022)
Objective: The use of thiazolidinediones (TZDs) as insulin sensitizers has been shown to have side effects including increased accumulation of bone marrow adipocytes (BMAds) associated with a higher fracture risk and bone loss. A novel TZD analog MSD
Externí odkaz:
https://doaj.org/article/069e2f335a58411aad710c3d1311ce2a
Autor:
Josef Oeckl, Petra Janovska, Katerina Adamcova, Kristina Bardova, Sarah Brunner, Sebastian Dieckmann, Josef Ecker, Tobias Fromme, Jiri Funda, Thomas Gantert, Piero Giansanti, Maria Soledad Hidrobo, Ondrej Kuda, Bernhard Kuster, Yongguo Li, Radek Pohl, Sabine Schmitt, Sabine Schweizer, Hans Zischka, Petr Zouhar, Jan Kopecky, Martin Klingenspor
Publikováno v:
Molecular Metabolism, Vol 61, Iss , Pp 101499- (2022)
Objective: Classical ATP-independent non-shivering thermogenesis enabled by uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) is activated, but not essential for survival, in the cold. It has long been suspected that futile ATP-consuming subs
Externí odkaz:
https://doaj.org/article/02a486b5a3c54c2cbc43e4898dd4d342
Autor:
Andrea Buresova‐Faitova, Jan Kopecky, Marketa Sagova‐Mareckova, Lise Alonso, Florian Vautrin, Yvan Moënne‐Loccoz, Veronica Rodriguez‐Nava
Publikováno v:
MicrobiologyOpen, Vol 11, Iss 2, Pp n/a-n/a (2022)
Abstract Actinobacteria are important cave inhabitants, but knowledge of how anthropization and anthropization‐related visual marks affect this community on cave walls is lacking. We compared Actinobacteria communities among four French limestone c
Externí odkaz:
https://doaj.org/article/1218081ebde546a98ddb82fe3a0e73e1
Autor:
Jiří Funda, Josep A. Villena, Kristina Bardova, Katerina Adamcova, Illaria Irodenko, Pavel Flachs, Ivana Jedlickova, Eliska Haasova, Martin Rossmeisl, Jan Kopecky, Petra Janovska
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 4 (2022)
Impaired thermogenesis observed in mice with whole-body ablation of peroxisome proliferator-activated receptor-γ coactivator-1β (PGC-1β; officially known as PPARGC1B) may result from impaired brown fat (brown adipose tissue; BAT) function, but oth
Externí odkaz:
https://doaj.org/article/8c32943251774e9cad944271328acd81