Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Jan Konopacki"'
Autor:
Malgorzata Urbanska, Paulina Kazmierska-Grebowska, Tomasz Kowalczyk, Bartosz Caban, Karolina Nader, Barbara Pijet, Katarzyna Kalita, Agata Gozdz, Herman Devijver, Benoit Lechat, Tomasz Jaworski, Wieslawa Grajkowska, Krzysztof Sadowski, Sergiusz Jozwiak, Katarzyna Kotulska, Jan Konopacki, Fred Van Leuven, Erwin A. van Vliet, Eleonora Aronica, Jacek Jaworski
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 377-387 (2019)
Background: Glycogen synthase kinase-3β (GSK3β) is a key regulator of cellular homeostasis. In neurons, GSK3β contributes to the control of neuronal transmission and plasticity, but its role in epilepsy remains to be defined. Methods: Biochemical
Externí odkaz:
https://doaj.org/article/ccb24ce7f72a4cd2a2d94b67aaf14db7
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206532 (2018)
BACKGROUND:Electrical vagal nerve stimulation (VNS) has been used for years to treat patients with drug-resistant epilepsy. This technique also remains under investigation as a specific treatment of patients with Alzheimer's disease. Recently we disc
Externí odkaz:
https://doaj.org/article/957f211466cf4eb78c4dc22f88383e8e
Autor:
Matylda Macias, Magdalena Blazejczyk, Paulina Kazmierska, Bartosz Caban, Agnieszka Skalecka, Bartosz Tarkowski, Anna Rodo, Jan Konopacki, Jacek Jaworski
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64455 (2013)
Mammalian target of rapamycin (mTOR) is a protein kinase that senses nutrient availability, trophic factors support, cellular energy level, cellular stress, and neurotransmitters and adjusts cellular metabolism accordingly. Adequate mTOR activity is
Externí odkaz:
https://doaj.org/article/f4082017b5e4443fb539dfecdb2c6876
Publikováno v:
Brain Research Bulletin. 155:37-47
Vagal nerve stimulation (VNS) is known as an effective method of treatment in a number of neurological disorders. The low risk of side effects also makes it useful in clinical trials in other diseases. Branches of the vagal nerve innervate the anatom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8ed10377e7f695668e0d8d7d3a3179
https://doi.org/10.1016/j.brainresbull.2019.11.011
https://doi.org/10.1016/j.brainresbull.2019.11.011
Publikováno v:
Neuroscience. 483
More than thirty years of medical treatment with the use of vagal nerve stimulation (VNS) has shown that this therapeutic procedure works in a number of homeostatic disturbances. Although the clinical usage of VNS has a long history, our knowledge ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b5cd08f10beef6e7afa977a041eadf
https://pubmed.ncbi.nlm.nih.gov/34952159
https://pubmed.ncbi.nlm.nih.gov/34952159
Publikováno v:
Brain Research Bulletin. 147:110-123
The key question to be answered in the present study was whether the medial septal GABAergic receptors are engaged in the pharmacological profile of the hippocampal formation (HPC) theta rhythm induced by vagal nerve stimulation (VNS). It was demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582757a885bcfe23659718bc7a7666f7
https://doi.org/10.1016/j.brainresbull.2019.02.010
https://doi.org/10.1016/j.brainresbull.2019.02.010
Autor:
Jacek Jaworski, Agata Gozdz, Katarzyna Kotulska, Jan Konopacki, Bartosz Caban, Katarzyna Kalita, Herman Devijver, Tomasz Kowalczyk, Tomasz Jaworski, Fred Van Leuven, Malgorzata Urbanska, Sergiusz Jozwiak, Wiesława Grajkowska, Karolina Nader, Erwin A. van Vliet, Eleonora Aronica, Paulina Kazmierska-Grebowska, Barbara Pijet, Benoit Lechat, Krzysztof Sadowski
Publikováno v:
EBioMedicine
EBIOMEDICINE, 39, 377-387. Elsevier
EBioMedicine, 39, 377-387. Elsevier BV
EBIOMEDICINE, 39, 377-387. Elsevier
EBioMedicine, 39, 377-387. Elsevier BV
Background: Glycogen synthase kinase-3β (GSK3β) is a key regulator of cellular homeostasis. In neurons, GSK3β contributes to the control of neuronal transmission and plasticity, but its role in epilepsy remains to be defined. Methods: Biochemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62494813dd2abd98e0a05da8c6d08f20
https://doi.org/10.1016/j.ebiom.2018.11.040
https://doi.org/10.1016/j.ebiom.2018.11.040
Publikováno v:
Neuroscience. 473
The present study was undertaken to identify the noradrenergic receptors underlying the production of hippocampal formation (HPC) type 2 theta rhythm. The experiments were performed on urethanized rats wherein type 2 theta is the only rhythm present.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edecc0965b9e11ecf7c143ec46ad6f64
https://pubmed.ncbi.nlm.nih.gov/34418519
https://pubmed.ncbi.nlm.nih.gov/34418519
Publikováno v:
Brain research bulletin. 162
Previously obtained data suggests that noradrenaline (NE) released from the efferent locus coeruleus (LC) endings in hippocampal formation (HPC) may serve as an important modulating signal involved in the pharmacological mechanisms responsible for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae0e155d29368adaef68ba9c39d37e0
https://pubmed.ncbi.nlm.nih.gov/32540420
https://pubmed.ncbi.nlm.nih.gov/32540420
Publikováno v:
Developmental Neurobiology. 78:1049-1063
Theta rhythms have been recorded from rat brain slices of the posterior hypothalamic area (PHa), including the supramammillary and posterior hypothalamic nuclei. Additionally, in numerous studies theta-related neurons were identified in the PHa accor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef1f5a70b01fe0067aedef8ee4a2a9c9
https://doi.org/10.1002/dneu.22628
https://doi.org/10.1002/dneu.22628