Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Jan Klohs"'
Autor:
Tim M. Emmenegger, Raoul Seiler, Paul G. Unschuld, Patrick Freund, Jan Klohs, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Alzheimer’s disease (AD) is characterized by progressive episodic memory dysfunction. A prominent hallmark of AD is gradual brain atrophy. Despite extensive research on brain pathology, the understanding of spinal cord pathology in AD and
Externí odkaz:
https://doaj.org/article/b0e4a03e3de04c5282b86746aa12b0b1
Autor:
Kevin Akeret, Raphael M. Buzzi, Bart R. Thomson, Nina Schwendinger, Jan Klohs, Nadja Schulthess-Lutz, Livio Baselgia, Kerstin Hansen, Luca Regli, Florence Vallelian, Michael Hugelshofer, Dominik J. Schaer
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background The functional neurological outcome of patients with intracerebral hemorrhage (ICH) strongly relates to the degree of secondary brain injury (ICH-SBI) evolving within days after the initial bleeding. Different mechanisms including
Externí odkaz:
https://doaj.org/article/4a7a33876f7449a5864e6b13cdfd5e77
Autor:
Ruiqing Ni, Nadja Straumann, Serana Fazio, Xose Luis Dean-Ben, Georgios Louloudis, Claudia Keller, Daniel Razansky, Simon Ametamey, Linjing Mu, César Nombela-Arrieta, Jan Klohs
Publikováno v:
Photoacoustics, Vol 32, Iss , Pp 100532- (2023)
Emerging evidence indicates crosstalk between the brain and hematopoietic system following cerebral ischemia. Here, we investigated metabolism and oxygenation in the spleen and spinal cord in a transient middle cerebral artery occlusion (tMCAO) model
Externí odkaz:
https://doaj.org/article/3965b1b689934382ac6f2fa77a2e5d10
Autor:
Kevin Akeret, Raphael Buzzi, Bart Thomson, Nina Schwendinger, Jan Klohs, Nadja Schulthess-Lutz, Livio Baselgia, Kerstin Hansen, Luca Regli, Florence Vallelian, Michael Hugelshofer, Dominik Schaer
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 101801- (2023)
Externí odkaz:
https://doaj.org/article/36117b6135264c589bb64e3378d47817
Autor:
Vasil Kecheliev, Francesco Spinelli, Adrienne Herde, Ahmed Haider, Linjing Mu, Jan Klohs, Simon M. Ametamey, Ruiqing Ni
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Neuroinflammation plays an important role in the pathophysiology of Alzheimer’s disease. The cannabinoid type 2 receptor (CB2R) is an emerging target for neuroinflammation and therapeutics of Alzheimer’s disease. Here, we aim to assess the altera
Externí odkaz:
https://doaj.org/article/188f49f4cba045b28e831825027dbe1d
Autor:
Jasmin Probst, Marco Rohner, Malin Zahn, Marco Piccirelli, Athina Pangalu, Andreas Luft, Andreas Deistung, Jan Klohs, Susanne Wegener
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Quantitative susceptibility mapping (QSM) is a novel processing method for gradient-echo magnetic resonance imaging (MRI). Higher magnetic susceptibility in cortical veins have been observed on susceptibility maps in the ischemic hemisphere
Externí odkaz:
https://doaj.org/article/23394c3ce1454226b8184af32fb54ff2
Autor:
Thomas Sartoretti, Robert P. Ganley, Ruiqing Ni, Patrick Freund, Hanns Ulrich Zeilhofer, Jan Klohs
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
In primary tauopathies, the deposition of tau neurofibrillary tangles and threads as well as neurodegenerative changes have been found within the brain and spinal cord. While degenerative changes have been intensively studied in the brain using struc
Externí odkaz:
https://doaj.org/article/c749cdcee4bc4df5b079d1a4c0912a54
Autor:
Georgios Louloudis, Samuele Ambrosini, Francesco Paneni, Giovanni G. Camici, Dietmar Benke, Jan Klohs
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Externí odkaz:
https://doaj.org/article/740be628812542f88cc874b21cbb3787
Autor:
Till de Bortoli, Philipp Boehm-Sturm, Stefan P. Koch, Melina Nieminen-Kelhä, Lars Wessels, Susanne Mueller, Giovanna D. Ielacqua, Jan Klohs, Peter Vajkoczy, Nils Hecht
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Purpose: Subsurface blood vessels in the cerebral cortex have been identified as a bottleneck in cerebral perfusion with the potential for collateral remodeling. However, valid techniques for non-invasive, longitudinal characterization of neocortical
Externí odkaz:
https://doaj.org/article/11bcb034aa864a1d82d3645863352de8
Autor:
Ruiqing Ni, Alessia Villois, Xose Luis Dean-Ben, Zhenyue Chen, Markus Vaas, Stavros Stavrakis, Gloria Shi, Andrew deMello, Chongzhao Ran, Daniel Razansky, Paolo Arosio, Jan Klohs
Publikováno v:
Photoacoustics, Vol 23, Iss , Pp 100285- (2021)
The abnormal deposition of fibrillar beta-amyloid (Aβ) deposits in the brain is one of the major histopathological hallmarks of Alzheimer’s disease (AD). Here, we characterized curcumin-derivative CRANAD-2 for multi-spectral optoacoustic tomograph
Externí odkaz:
https://doaj.org/article/d970e936b9074e9796de4a0f234f0cb8