Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jan Kempski"'
Autor:
Tao Zhang, Philipp Seeger, Yashin Simsek, Morsal Sabihi, Jöran Lücke, Dimitra E. Zazara, Ahmad Mustafa Shiri, Jan Kempski, Tom Blankenburg, Lilan Zhao, Ioannis Belios, Andres Machicote, Baris Mercanoglu, Mohammad Fard-Aghaie, Sara Notz, Panagis M. Lykoudis, Marius Kemper, Tarik Ghadban, Oliver Mann, Thilo Hackert, Jakob R. Izbicki, Thomas Renné, Samuel Huber, Anastasios D. Giannou, Jun Li
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27578- (2024)
Background: Insufficient remnant liver volume (RLV) after the resection of hepatic malignancy could lead to liver failure and mortality. Portal vein ligation (PVL) prior to hepatectomy is subsequently introduced to increase the remnant liver volume a
Externí odkaz:
https://doaj.org/article/e149ef093eb041cda71966c12d3904a4
Autor:
Friederike Stumme, Niklas Steffens, Babett Steglich, Franziska Mathies, Mikolaj Nawrocki, Morsal Sabihi, Shiwa Soukou-Wargalla, Emilia Göke, Jan Kempski, Thorben Fründt, Sören Weidemann, Christoph Schramm, Nicola Gagliani, Samuel Huber, Tanja Bedke
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPrimary sclerosing cholangitis (PSC) is a chronic liver disease marked by inflammation of the bile ducts and results in the development of strictures and fibrosis. A robust clinical correlation exists between PSC and inflammatory bowel dise
Externí odkaz:
https://doaj.org/article/fe4be545b6ce4708b789790c53a8eb4c
Autor:
Jöran Lücke, Marius Böttcher, Mikolaj Nawrocki, Nicholas Meins, Josa Schnell, Fabian Heinrich, Franziska Bertram, Morsal Sabihi, Philipp Seeger, Marie Pfaff, Sara Notz, Tom Blankenburg, Tao Zhang, Jan Kempski, Matthias Reeh, Stefan Wolter, Oliver Mann, Marc Lütgehetmann, Thilo Hackert, Jakob R. Izbicki, Anna Duprée, Samuel Huber, Benjamin Ondruschka, Anastasios D. Giannou
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24508- (2024)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which is responsible for eliciting Coronavirus disease 2019 (COVID-19) still challenges healthcare services worldwide. While many patients only suffer from mild symptoms, patients with
Externí odkaz:
https://doaj.org/article/97a65152e90641b19afff3d1c19eb223
Autor:
Tao Zhang, Ramez Wahib, Dimitra E. Zazara, Jöran Lücke, Ahmad Mustafa Shiri, Jan Kempski, Lilan Zhao, Theodora Agalioti, Andres Pablo Machicote, Olympia Giannou, Ioannis Belios, Rongrong Jia, Siwen Zhang, Joseph Tintelnot, Hannes Seese, Julia Kristin Grass, Baris Mercanoglu, Louisa Stern, Pasquale Scognamiglio, Mohammad Fard-Aghaie, Philipp Seeger, Jonas Wakker, Marius Kemper, Benjamin Brunswig, Anna Duprée, Panagis M. Lykoudis, Anastasia Pikouli, Emmanouil Giorgakis, Pablo Stringa, Natalia Lausada, Maria Virginia Gentilini, Gabriel E. Gondolesi, Kai Bachmann, Philipp Busch, Rainer Grotelüschen, Ioannis C. Maroulis, Petra C. Arck, Ryosuke Nakano, Angus W. Thomson, Tarik Ghadban, Michael Tachezy, Nathaniel Melling, Eike-Gert Achilles, Victor G. Puelles, Felix Nickel, Thilo Hackert, Oliver Mann, Jakob R. Izbicki, Jun Li, Nicola Gagliani, Samuel Huber, Anastasios D. Giannou
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTMetastasis is a cancer-related systemic disease and is responsible for the greatest mortality rate among cancer patients. Interestingly, the interaction between the immune system and cancer cells seems to play a key role in metastasis formati
Externí odkaz:
https://doaj.org/article/3cee1dcf7a0d46038cb4bbb3cfb81bcf
Autor:
Anastasios D. Giannou, Jan Kempski, Tao Zhang, Jöran Lücke, Ahmad Mustafa Shiri, Dimitra E. Zazara, Ioannis Belios, Andres Machicote, Philipp Seeger, Theodora Agalioti, Joseph Tintelnot, Adrian Sagebiel, Miriam Tomczak, Lennart Bauditz, Tanja Bedke, Lorenz Kocheise, Baris Mercanoglu, Mohammad Fard-Aghaie, Emmanouil Giorgakis, Panagis M. Lykoudis, Anastasia Pikouli, Julia-Kristin Grass, Ramez Wahib, Jan Bardenhagen, Benjamin Brunswig, Asmus Heumann, Tarik Ghadban, Anna Duprée, Michael Tachezy, Nathaniel Melling, Petra C. Arck, Pablo Stringa, Maria Virginia Gentilini, Gabriel E. Gondolesi, Ryosuke Nakano, Angus W. Thomson, Daniel Perez, Jun Li, Oliver Mann, Jakob R. Izbicki, Nicola Gagliani, Ioannis C. Maroulis, Samuel Huber
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe immune system plays a pivotal role in cancer progression. Interleukin 22 binding protein (IL-22BP), a natural antagonist of the cytokine interleukin 22 (IL-22) has been shown to control the progression of colorectal cancer (CRC). Howeve
Externí odkaz:
https://doaj.org/article/f1277168178b412eb2f6bc3aef5b86d5
Autor:
Christopher Dietz-Fricke, Frank Tacke, Caroline Zöllner, Münevver Demir, Hartmut H. Schmidt, Christoph Schramm, Katharina Willuweit, Christian M. Lange, Sabine Weber, Gerald Denk, Christoph P. Berg, Julia M. Grottenthaler, Uta Merle, Alexander Olkus, Stefan Zeuzem, Kathrin Sprinzl, Thomas Berg, Florian van Bömmel, Johannes Wiegand, Toni Herta, Thomas Seufferlein, Eugen Zizer, Nektarios Dikopoulos, Robert Thimme, Christoph Neumann-Haefelin, Peter R. Galle, Martin Sprinzl, Ansgar W. Lohse, Julian Schulze zur Wiesch, Jan Kempski, Andreas Geier, Florian P. Reiter, Bernhard Schlevogt, Juliana Gödiker, Wolf Peter Hofmann, Peter Buggisch, Julia Kahlhöfer, Kerstin Port, Benjamin Maasoumy, Markus Cornberg, Heiner Wedemeyer, Katja Deterding
Publikováno v:
JHEP Reports, Vol 5, Iss 4, Pp 100686- (2023)
Background & Aims: Bulevirtide is a first-in-class entry inhibitor of hepatitis B surface antigen. In July 2020, bulevirtide was conditionally approved for the treatment of hepatitis D, the most severe form of viral hepatitis, which frequently causes
Externí odkaz:
https://doaj.org/article/25235c3dba9540059b007583dc50c8da
Autor:
Jöran Lücke, Mikolaj Nawrocki, Josa Schnell, Nicholas Meins, Fabian Heinrich, Tao Zhang, Franziska Bertram, Morsal Sabihi, Marius Böttcher, Tom Blankenburg, Marie Pfaff, Sara Notz, Jan Kempski, Matthias Reeh, Stefan Wolter, Oliver Mann, Jakob R. Izbicki, Marc Lütgehetmann, Anna Duprée, Anastasios D. Giannou, Benjamin Ondruschka, Samuel Huber
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus does not only lead to pulmonary infection but can also infect other organs such as the gut, the kidney, or the liver. Recent
Externí odkaz:
https://doaj.org/article/189b81ba144b45d58c6bedc5167cda2a
Autor:
Anastasios D. Giannou, Jöran Lücke, Dörte Kleinschmidt, Ahmad Mustafa Shiri, Babett Steglich, Mikolaj Nawrocki, Tao Zhang, Dimitra E. Zazara, Jan Kempski, Lilan Zhao, Olympia Giannou, Theodora Agalioti, Leonie Brockmann, Franziska Bertram, Morsal Sabihi, Marius Böttcher, Florian Ewald, Kornelius Schulze, Johann von Felden, Andres Machicote, Ioannis C. Maroulis, Petra C. Arck, Julia-Kristin Graß, Baris Mercanoglu, Matthias Reeh, Stefan Wolter, Michael Tachezy, Hannes Seese, Myrto Theodorakopoulou, Panagis M. Lykoudis, Asmus Heumann, Faik G. Uzunoglu, Tarik Ghadban, Oliver Mann, Jakob R. Izbicki, Jun Li, Anna Duprée, Nathaniel Melling, Nicola Gagliani, Samuel Huber
Publikováno v:
Cancers, Vol 14, Iss 24, p 6019 (2022)
Hepatocellular carcinoma (HCC) ranks among the five most common cancer entities worldwide and leads to hundred-thousands of deaths every year. Despite some groundbreaking therapeutical revelations during the last years, the overall prognosis remains
Externí odkaz:
https://doaj.org/article/60528250508c49eb85f051164148486c
Autor:
Laura Garcia Perez, Jan Kempski, Heather M. McGee, Penelope Pelzcar, Theodora Agalioti, Anastasios Giannou, Leonie Konczalla, Leonie Brockmann, Ramez Wahib, Hao Xu, Maria Carolina Amezcua Vesely, Shiwa Soukou, Babett Steglich, Tanja Bedke, Carolin Manthey, Oliver Seiz, Björn-Philipp Diercks, Stylianos Gnafakis, Andreas H. Guse, Daniel Perez, Jakob R. Izbicki, Nicola Gagliani, Richard A. Flavell, Samuel Huber
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Poly-functional helper T cells can have a stronger effect than mono-functional T cells, but whether the response is qualitatively different is not clear. Here the authors show that a population of IL-17+IL-22+, but not single IL-22+, CD4+ T cells are
Externí odkaz:
https://doaj.org/article/b2cd0a9890934f83bc2a0f45b98be1cc
Autor:
Karl-Frederick Karstens, Jan Kempski, Anastasios D Giannou, Erik Freiwald, Matthias Reeh, Michael Tachezy, Jakob R Izbicki, Ansgar W Lohse, Nicola Gagliani, Samuel Huber, Penelope Pelczar
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231833 (2020)
INTRODUCTION:Reflux promotes esophageal adenocarcinomas (EAC) creating a chronic inflammatory environment. EAC show an increasing incidence in the Western World and median survival rates are still low. The main reasons for poor prognosis despite new
Externí odkaz:
https://doaj.org/article/4ac7d1384f024219ad68caf4f1be948e