Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jan K, Blusztajn"'
Autor:
Thomas A Bellio, Jessenia Y Laguna-Torres, Mary S Campion, Jay Chou, Sheila Yee, Jan K Blusztajn, Tiffany J Mellott
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0297289 (2024)
Alzheimer's disease (AD) is characterized by cognitive and memory impairments and neuropathological abnormalities. AD has no cure, inadequate treatment options, and a limited understanding of possible prevention measures. Previous studies have demons
Externí odkaz:
https://doaj.org/article/ccb9e7ed631a421c88df72e0ddc9514f
Publikováno v:
Non-Coding RNA, Vol 7, Iss 1, p 8 (2021)
The neurological damage of Alzheimer’s disease (AD) is thought to be irreversible upon onset of dementia-like symptoms, as it takes years to decades for occult pathologic changes to become symptomatic. It is thus necessary to identify individuals a
Externí odkaz:
https://doaj.org/article/6c8e4056c1a14a139ce213a19696ff99
Autor:
Tiffany J Mellott, Olivia M Huleatt, Bethany N Shade, Sarah M Pender, Yi B Liu, Barbara E Slack, Jan K Blusztajn
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174875 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0170450.].
Externí odkaz:
https://doaj.org/article/fd11d2ebe93a44a38261666c73f0ac51
Autor:
Tiffany J Mellott, Olivia M Huleatt, Bethany N Shade, Sarah M Pender, Yi B Liu, Barbara E Slack, Jan K Blusztajn
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170450 (2017)
Prevention of Alzheimer's disease (AD) is a major goal of biomedical sciences. In previous studies we showed that high intake of the essential nutrient, choline, during gestation prevented age-related memory decline in a rat model. In this study we i
Externí odkaz:
https://doaj.org/article/b87ba5620aff442b90fb45e2acfb2181
Autor:
Sarah J.E. Wong-Goodrich, Tiffany J. Mellott, Melissa J. Glenn, Jan K. Blusztajn, Christina L. Williams
Publikováno v:
Neurobiology of Disease, Vol 30, Iss 2, Pp 255-269 (2008)
Prenatal choline supplementation (SUP) protects adult rats against spatial memory deficits observed after excitotoxin-induced status epilepticus (SE). To examine the mechanism underlying this neuroprotection, we determined the effects of SUP on a var
Externí odkaz:
https://doaj.org/article/3e9d41a85c094fe383336c4b78bfa5fb
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21166 (2011)
Cholinergic projection from the septum to the hippocampus is crucial for normal cognitive function and degeneration of cells and nerve fibers within the septohippocampal pathway contributes to the pathophysiology of Alzheimer's disease. Bone morphoge
Externí odkaz:
https://doaj.org/article/b1d97cca8364409a959065d2660b1586
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 2 (2008)
In order to determine brain and behavioral sensitivity of nutrients that may serve as inductive signals during early development, we altered choline availability to rats during 7 time frames spanning embryonic day (ED) 6 through postnatal day (PD) 75
Externí odkaz:
https://doaj.org/article/a709e9386fea4ee19c313529e39ac015
Autor:
Melissa J, Glenn, Erin M, Gibson, Elizabeth D, Kirby, Tiffany J, Mellott, Jan K, Blusztajn, Christina L, Williams
Publikováno v:
The European journal of neuroscience. 25(8)
Increased dietary intake of choline early in life improves performance of adult rats on memory tasks and prevents their age-related memory decline. Because neurogenesis in the adult hippocampus also declines with age, we investigated whether prenatal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42b30b2c6bc34841d41b2c335f6b2cd4
https://pubmed.ncbi.nlm.nih.gov/17445242
https://pubmed.ncbi.nlm.nih.gov/17445242
Cholinergic properties of the SN56.B5.G4 cell line derived from the fusion of neurons of the mouse postnatal day 21 septum and the murine neuroblastoma cell line N18TG2 were investigated and correlated with morphological differentiation. In basal ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a90b80508f5ccb5eb151730fab83164
https://europepmc.org/articles/PMC6576034/
https://europepmc.org/articles/PMC6576034/
Autor:
Andrzej Szutowicz, Jan K. Blusztajn
Publikováno v:
Metabolic Brain Disease. 15:i-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0bc52648bbfe85441245b0733d72c10
https://doi.org/10.1007/bf02680009
https://doi.org/10.1007/bf02680009