Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jan Jamroskovic"'
Autor:
Jan Jamroskovic, Zuzana Chromikova, Cornelia List, Barbora Bartova, Imrich Barak, Rizlan Bernier-Latmani
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
Spores of a number of clostridial species, and their resistance to thermal treatment is a major concern for the food industry. Spore resistance to wet heat is related to the level of spore hydration, which is inversely correlated with the content of
Externí odkaz:
https://doaj.org/article/5d5840a43fce4afda52849dd9d54e12f
Autor:
Jan Jamroskovic, Erik Chorell, Matilda Rentoft, Vandana Singh, Nasim Sabouri, Karam Chand, Fredrik Westerlund, Ikenna Obi
Publikováno v:
Nucleic Acids Research
G-quadruplex (G4) structures are stable non-canonical DNA structures that are implicated in the regulation of many cellular pathways. We show here that the G4-stabilizing compound PhenDC3 causes growth defects in Schizosaccharomyces pombe cells, espe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e57ca5e09a0e52ef5403d25fa699a9
https://doi.org/10.1093/nar/gkaa820
https://doi.org/10.1093/nar/gkaa820
Autor:
Rabindra Nath Das, Rajendra Kumar, Mattias Hedenström, Jan Jamroskovic, Erik Chorell, Nasim Sabouri, Bagineni Prasad
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
G‐quadruplex (G4) DNA structures are linked to fundamental biological processes and human diseases, which has triggered the development of compounds that affect these DNA structures. However, more knowledge is needed about how small molecules inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215a7c61938d9f0883621345b2ca676a
http://europepmc.org/articles/PMC7497243
http://europepmc.org/articles/PMC7497243
Publikováno v:
Angewandte Chemie International Edition. 59:896-902
The design of turn-on dyes with optical signals sensitive to the formation of supramolecular structures provides fascinating and underexplored opportunities for G-quadruplex (G4) DNA detection and characterization. Here, we show a new switching mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d66ac9c26b8bf754d663a59a9af8bc1
https://doi.org/10.1002/anie.201912027
https://doi.org/10.1002/anie.201912027
Publikováno v:
Biochimie. 199
Cytosine-rich DNA can fold into four-stranded intercalated structures called i-motifs (iMs) under acidic conditions through the formation of hemi-protonated C:C+ base pairs. However, the folding and stability of iMs rely on many other factors that ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ffe3a3a1b88012263b608ef324cce7d
https://pubmed.ncbi.nlm.nih.gov/35452743
https://pubmed.ncbi.nlm.nih.gov/35452743
Cytosine-rich DNA can fold into four-stranded intercalated structures, i-motif (iM), in acidic pH and require hemi-protonated C:C+ base pairs to form. However, its formation and stability rely on many other factors that are not yet fully understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c037f1518c6402117d29a51cd142223f
https://doi.org/10.1101/2022.01.05.475026
https://doi.org/10.1101/2022.01.05.475026
Publikováno v:
Chemical communications (Cambridge, England). 56(91)
Phen-DC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d08723e6a5d0a9a2954f984d0281675
https://pubmed.ncbi.nlm.nih.gov/33118567
https://pubmed.ncbi.nlm.nih.gov/33118567
Autor:
Rajendra Kumar, Kazutoshi Kasho, Ikenna Obi, Kristoffer Brännström, Rabindra Nath Das, Parham L. Pourbozorgi, James E. Mason, Jan Jamroskovic, Nasim Sabouri, Mattias Hedenström, Mara Doimo, Sjoerd Wanrooij, Sebastian Sulis Sato, Marco Deiana, Erik Chorell, Almaz Akhunzianov, Paolo Medini, Daniel Öhlund, Karam Chand
Publikováno v:
Journal of the American Chemical Society
The signal transducer and activator of transcription 3 (STAT3) protein is a master regulator of most key hallmarks and enablers of cancer, including cell proliferation and the response to DNA damage. G-Quadruplex (G4) structures are four-stranded non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65413fad2479ca1592337e387af21cd
https://pubmed.ncbi.nlm.nih.gov/31990532
https://pubmed.ncbi.nlm.nih.gov/31990532
Autor:
Karam Chand, Erik Chorell, Rabindra Nath Das, Jan Jamroskovic, Marco Deiana, Ikenna Obi, Nasim Sabouri
Direct and unambiguous evidence of the formation of G-quadruplexes (G4s) in human cells have shown their implication in several key biological events and has emphasized their role as important targets for small-molecule cancer therapeutics. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0b284e9afbee66b0efffd7dc27363b
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-171513
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-171513
Phen-DC3 is among the most commonly used G-quadruplex (G4)-stabilizers in vitro and in cells. Here, we show that the G4-interactive binding interactions enable one to tune the optical properties of Phen-DC3 allowing the detection of G4 structures in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36285b606ac627771b83d07caed4cec3
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-176333
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-176333