Zobrazeno 1 - 10
of 1 847
pro vyhledávání: '"Jan Jacob"'
Autor:
Shanna M. Hogeling, Duy Minh Lê, Nikita La Rose, Min Chul Kwon, Albertus T.J. Wierenga, Fiona A.J. van den Heuvel, Vincent van den Boom, Anna Kuchnio, Ulrike Philippar, Gerwin Huls, Jan Jacob Schuringa
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Acute myeloid leukemia (AML) remains challenging to treat, which in part relates to genetic heterogeneity of the disease, to the protective tumor microenvironment driving resistance to therapy, and also to immune evasion characteristics of leukemic c
Externí odkaz:
https://doaj.org/article/b12e34c2d21c432d86cb3d9b8a8be138
Autor:
Casper Craamer, Thomas Timmers, Michiel Siebelt, Rudolf Bertijn Kool, Carel Diekerhof, Jan Jacob Caron, Taco Gosens, Walter van der Weegen
Publikováno v:
JMIR Medical Informatics, Vol 12, Pp e60655-e60655 (2024)
Abstract BackgroundCollecting the medical history during a first outpatient consultation plays an important role in making a diagnosis. However, it is a time-consuming process, and time is scarce in today’s health care environment. The computer-as
Externí odkaz:
https://doaj.org/article/24a1faea6d6d4740866a2bb9b0c56203
Autor:
Dimitrios Kleftogiannnis, Sonia Gavasso, Benedicte Sjo Tislevoll, Nisha van der Meer, Inga K.F. Motzfeldt, Monica Hellesøy, Stein-Erik Gullaksen, Emmanuel Griessinger, Oda Fagerholt, Andrea Lenartova, Yngvar Fløisand, Jan Jacob Schuringa, Bjørn Tore Gjertsen, Inge Jonassen
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110261- (2024)
Summary: Mass cytometry by time-of-flight (CyTOF) is an emerging technology allowing for in-depth characterization of cellular heterogeneity in cancer and other diseases. Unfortunately, high-dimensional analyses of CyTOF data remain quite demanding.
Externí odkaz:
https://doaj.org/article/003d137f2d7f4c8881fa8678f31e47b1
Autor:
Yusheng Lin, Ghizlane Choukrani, Lena Dubbel, Lena Rockstein, Jimena Alvarez Freile, Yuzhu Qi, Valerie Wiersma, Hao Zhang, Karl-Wilhelm Koch, Emanuele Ammatuna, Jan Jacob Schuringa, Tom van Meerten, Gerwin Huls, Edwin Bremer
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-18 (2024)
Abstract Background VISTA is a well-known immune checkpoint in T cell biology, but its role in innate immunity is less established. Here, we investigated the role of VISTA on anticancer macrophage immunity, with a focus on phagocytosis, macrophage po
Externí odkaz:
https://doaj.org/article/60adcfc1ae254d998496249d73aaad31
Autor:
Nienke Visser, Levi Collin Nelemans, Yuan He, Harm Jan Lourens, Macarena González Corrales, Gerwin Huls, Valerie R. Wiersma, Jan Jacob Schuringa, Edwin Bremer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In recent years, the therapeutic (re)activation of innate anticancer immunity has gained prominence, with therapeutic blocking of the interaction of Signal Regulatory Protein (SIRP)-α with its ligand CD47 yielding complete responses in refractory an
Externí odkaz:
https://doaj.org/article/433d8659aff946d7b49c0e7573e80c22
Autor:
Priscilla Kamphuis, Isabelle A. van Zeventer, Aniek O. de Graaf, Giulio Genovese, Jonas B. Salzbrunn, Avinash G. Dinmohamed, Bert A. van der Reijden, Jan Jacob Schuringa, Joop H. Jansen, Gerwin Huls
Publikováno v:
HemaSphere, Vol 7, Iss 10, p e956 (2023)
Externí odkaz:
https://doaj.org/article/afcc11b0a3ec490a80013e9d69a25b7e
Autor:
Keli Lima, Diego Antonio Pereira-Martins, Lívia Bassani Lins de Miranda, Juan Luiz Coelho-Silva, Giovana da Silva Leandro, Isabel Weinhäuser, Rita de Cássia Cavaglieri, Aline de Medeiros Leal, Wellington Fernandes da Silva, Ana Paula Alencar de Lima Lange, Elvira Deolinda Rodrigues Pereira Velloso, Emmanuel Griessinger, Jacobien R. Hilberink, Emanuele Ammatuna, Gerwin Huls, Jan Jacob Schuringa, Eduardo Magalhães Rego, João Agostinho Machado-Neto
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 11, Pp 1-11 (2022)
Abstract The treatment of acute leukemia is challenging because of the genetic heterogeneity between and within patients. Leukemic stem cells (LSCs) are relatively drug-resistant and frequently relapse. Their plasticity and capacity to adapt to extra
Externí odkaz:
https://doaj.org/article/b16e466524024a6e89b2c001afb981b4
Autor:
Isabel Weinhäuser, Diego A. Pereira-Martins, Jacobien R. Hilberink, Annet Brouwers-Vos, Eduardo M. Rego, Gerwin Huls, Jan Jacob Schuringa
Publikováno v:
Haematologica, Vol 109, Iss 2 (2023)
Externí odkaz:
https://doaj.org/article/a6032b8c6c124d25b2bc7e7184f7b3c6
Autor:
Diego A Pereira-Martins, César Alexander Ortiz Rojas, Isabel Weinhauser, Douglas Silveira, Albertus T J Wierenga, Vincent van den Boom, Thiago M Bianco, Emanuele Ammatuna, Lynn Quek, Antonio R Lucena-Araujo, Gerwin Huls, Eduardo Rego, Jan Jacob Schuringa
Publikováno v:
HemaSphere, Vol 7, p e179931b (2023)
Externí odkaz:
https://doaj.org/article/5fedf24a1fb64b159457d1244ae87bd2
Autor:
Diego A Pereira-Martins, Vincent van den Boom, Noortje van Dijk, Isabel Weinhauser, Douglas Silveira, Thiago M Bianco, César Alexander Ortiz Rojas, Gerwin Huls, Lynn Quek, Antonio R Lucena-Araujo, Eduardo Rego, Jan Jacob Schuringa
Publikováno v:
HemaSphere, Vol 7, p e7326920 (2023)
Externí odkaz:
https://doaj.org/article/2f4c0c158a5141bb97492b1f5eec75ce