Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jan J.B. Boesen"'
Autor:
Patrick Hundsdörfer, Raimund Höft, D. A. Breems, W. Jens Zeller, Stefan Fruehauf, Bob Löwenberg, Dinko Valerio, Rainer Haas, Jan J.B. Boesen, Rob E. Ploemacher
Publikováno v:
Stem Cells. 13:93-99
Transfer of the multidrug resistance-1 (MDR1) gene to hemopoietic cells for myeloprotection against cytostatic agents is a new and rapidly developing field in "cancer gene therapy." Before clinical application, safety and efficacy criteria need to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::883168d159f53d23debf13a45643a317
https://doi.org/10.1002/stem.5530130715
https://doi.org/10.1002/stem.5530130715
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 307:121-129
The Luria-Delbruck fluctuation analysis provides a method to estimate mutation rates and is commonly applied in somatic cell genetics and in cancer biology. We developed an assay for a Luria-Delbruck fluctuation analysis using the mouse lymphoma cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560ece7cf106890cbb874547caa5b387
https://doi.org/10.1016/0027-5107(94)90284-4
https://doi.org/10.1016/0027-5107(94)90284-4
Publikováno v:
Biotherapy (Dordrecht, Netherlands). 6(4)
Drug-induced myelosuppression is a frequent reason for curtailing chemotherapy in cancer patients. 'Rescue' of myelosuppressed patients with autologous marrow transplants is reasonably advanced and permits an increase in the dose of anticancer drugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af78a867ad7877649eed77a2f030244
https://pubmed.ncbi.nlm.nih.gov/7912537
https://pubmed.ncbi.nlm.nih.gov/7912537
Publikováno v:
Carcinogenesis. 13(12)
Ultraviolet irradiation triggers a response in mammalian cells known as the UV response. Part of the UV response forms the enhanced synthesis of various extracellular proteins able to transmit the response to non-irradiated cells. Because several can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06447ad3fa551697d2e5aa1e4546cb22
https://pubmed.ncbi.nlm.nih.gov/1473251
https://pubmed.ncbi.nlm.nih.gov/1473251
Autor:
J.W.I.M. Simons, Sandrine Stuivenberg, Jan J.B. Boesen, Paul H.M. Lohman, Henk Panneman, Corné H. M. Thyssens, Firouz Darroudi
Publikováno v:
Moleculargeneral genetics : MGG. 234(2)
Cells of the mouse T-lymphoma line GRSL13 were treated with 8-methoxy-psoralen plus longwave ultraviolet light (PUVA) under conditions where the biological effects are mainly due to non-persistent DNA cross-links (PUVA-CL treatment). Fluctuation anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430a58b22da55c372fc8cac36c1035e7
https://pubmed.ncbi.nlm.nih.gov/1508148
https://pubmed.ncbi.nlm.nih.gov/1508148
Publikováno v:
Carcinogenesis. 12(3)
The hypothesis that activation of the signal transduction pathways by environmental stress may lead to genetic instability was tested. Mouse T-lymphoma cells, GRSL13, were treated with the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a817125da3dae5e8d0019600361e7f9
https://pubmed.ncbi.nlm.nih.gov/2009594
https://pubmed.ncbi.nlm.nih.gov/2009594