A Single Conserved Amino Acid Residue as a Critical Context-Specific Determinant of the Differential Ability of Mdm2 and MdmX RING Domains to Dimerize

Autor: Pavlína Kosztyu, Iva Slaninová, Barbora Valčíková, Amandine Verlande, Petr Müller, Jan J. Paleček, Stjepan Uldrijan

Publikováno v: Frontiers in Physiology, Vol 10 (2019)

Mdm2 and MdmX are related proteins serving in the form of the Mdm2 homodimer or Mdm2/MdmX heterodimer as an E3 ubiquitin ligase for the tumor suppressor p53. The dimerization is required for the E3 activity and is mediated by the conserved RING domai

Externí odkaz: https://doaj.org/article/8d7027099b474166bebd2289da2b02c5

Correction: Kolesar et al. Role of Nse1 Subunit of SMC5/6 Complex as a Ubiquitin Ligase. Cells 2022, 11, 165

Autor: Peter Kolesar, Karel Stejskal, David Potesil, Johanne M. Murray, Jan J. Palecek

Publikováno v: Cells, Vol 13, Iss 10, p 812 (2024)

In the original publication [...]

Externí odkaz: https://doaj.org/article/a1d25c6906144eab87e48379f23b7788

A role of the Nse4 kleisin and Nse1/Nse3 KITE subunits in the ATPase cycle of SMC5/6

Autor: Lucie Vondrova, Peter Kolesar, Marek Adamus, Matej Nociar, Antony W. Oliver, Jan J. Palecek

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)

Abstract The SMC (Structural Maintenance of Chromosomes) complexes are composed of SMC dimers, kleisin and kleisin-interacting (HAWK or KITE) subunits. Mutual interactions of these subunits constitute the basal architecture of the SMC complexes. In a

Externí odkaz: https://doaj.org/article/c65c459f638e40849aacc4d743d98a78

Completing the TRB family: newly characterized members show ancient evolutionary origins and distinct localization, yet similar interactions.

Autor: Kusová A; Laboratory of Functional Genomics and Proteomics, Faculty of Science, National Centre for Biomolecular Research, Masaryk University, Brno, Czech Republic.; Mendel Centre for Plant Genomics and Proteomics, Central European Institute of Technology, Masaryk University, Brno, Czech Republic., Steinbachová L; Laboratory of Pollen Biology, Institute of Experimental Botany of the Czech Academy of Sciences, Prague, Czech Republic., Přerovská T; Laboratory of Functional Genomics and Proteomics, Faculty of Science, National Centre for Biomolecular Research, Masaryk University, Brno, Czech Republic., Drábková LZ; Laboratory of Pollen Biology, Institute of Experimental Botany of the Czech Academy of Sciences, Prague, Czech Republic., Paleček J; Laboratory of Functional Genomics and Proteomics, Faculty of Science, National Centre for Biomolecular Research, Masaryk University, Brno, Czech Republic.; Mendel Centre for Plant Genomics and Proteomics, Central European Institute of Technology, Masaryk University, Brno, Czech Republic., Khan A; Institute of Plant Molecular Biology, Biology Centre of the Czech Academy of Sciences, České Budějovice, Czech Republic., Rigóová G; Laboratory of Functional Genomics and Proteomics, Faculty of Science, National Centre for Biomolecular Research, Masaryk University, Brno, Czech Republic., Gadiou Z; Laboratory of Pollen Biology, Institute of Experimental Botany of the Czech Academy of Sciences, Prague, Czech Republic., Jourdain C; Institute of Biology, Freie Universität Berlin, 14195, Berlin, Germany., Stricker T; Institute of Biology, Freie Universität Berlin, 14195, Berlin, Germany., Schubert D; Institute of Biology, Freie Universität Berlin, 14195, Berlin, Germany., Honys D; Laboratory of Pollen Biology, Institute of Experimental Botany of the Czech Academy of Sciences, Prague, Czech Republic.; Department of Experimental Plant Biology, Faculty of Science, Charles University, Prague, Czech Republic., Schrumpfová PP; Laboratory of Functional Genomics and Proteomics, Faculty of Science, National Centre for Biomolecular Research, Masaryk University, Brno, Czech Republic. schpetra@sci.muni.cz.; Mendel Centre for Plant Genomics and Proteomics, Central European Institute of Technology, Masaryk University, Brno, Czech Republic. schpetra@sci.muni.cz.

Publikováno v: Plant molecular biology [Plant Mol Biol] 2023 May; Vol. 112 (1-2), pp. 61-83. Date of Electronic Publication: 2023 Apr 28.

Thyroid nodules and thyroid cancer in women with positive thyroid screening in pregnancy: a double-centric, retrospective, cohort study.

Autor: Jiskra J; 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic., Horáček J; 4th Department of Medicine, Faculty of Medicine, Charles University, University Hospital Hradec Králové, Czech Republic., Špitálníková S; Department of Nuclear Medicine, District Hospital, Havlíčkův Brod, Czech Republic., Paleček J; 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic., Límanová Z; 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic., Krátký J; 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic., Springer D; Department of Clinical Biochemistry and Laboratory Diagnostics, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic., Žabková K; 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic., Vítková H; 3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic.

Publikováno v: European thyroid journal [Eur Thyroid J] 2022 Feb 28; Vol. 11 (2). Date of Electronic Publication: 2022 Feb 28.