Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jan Huertas"'
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 6, p e1009013 (2021)
Genomic DNA is packaged in chromatin, a dynamic fiber variable in size and compaction. In chromatin, repeating nucleosome units wrap 145-147 DNA basepairs around histone proteins. Genetic and epigenetic regulation of genes relies on structural transi
Externí odkaz:
https://doaj.org/article/b4e48b939993434cbadbf973f4a83a34
Publikováno v:
Biophysical Journal. 122:170a
Publikováno v:
Current opinion in cell biology. 75
The three-dimensional organisation of the genome modulates biological processes and is, in turn, transformed by the activity in the nucleus. Not surprisingly, understanding how the genome operates requires uncovering the fundamental biophysical and m
Autor:
vom Bruch H, Ortmeier C, Hans R. Schöler, Cojocaru, Caitlin M. MacCarthy, Reinke D, Sander A, Jan Huertas, Bergbrede T
Pioneer transcription factors are proteins that induce cellular identity transitions by binding to inaccessible regions of DNA in nuclear chromatin. They contribute to chromatin opening and recruit other factors to regulatory DNA elements. The struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d603bb2df16c1a540d557da24242889
https://doi.org/10.1101/2021.04.27.441583
https://doi.org/10.1101/2021.04.27.441583
Autor:
Jan Huertas, Vlad Cojocaru
Publikováno v:
Journal of molecular biology.
Gene regulation programs establish cellular identity and rely on dynamic changes in the structural packaging of genomic DNA. The DNA is packaged in chromatin, which is formed from arrays of nucleosomes displaying different degree of compaction and di
Genomic DNA is packaged in chromatin, a dynamic polymer that forms fibers variable in size and compaction. Chromatin9s monomeric unit, the nucleosome, is formed by wrapping ~ 146 basepairs of DNA around histone proteins. Dynamic transitions in the ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7c5a757a4a662ff931832d98cdd88bf
https://doi.org/10.1101/2020.09.04.282921
https://doi.org/10.1101/2020.09.04.282921
Publikováno v:
Biophysical Journal. 121:5a
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Biophysical Journal. 120:139a
Autor:
David Grill, Simone Mengoni, Volker Gerke, Robert Ahrends, Andreas Hentschel, Monika Biasizzo, Tanumoy Saha, Julia Lehrich, Mirsana P. Ebrahimkutty, Jürgen Klingauf, Philipp Selenschik, Vlad Cojocaru, Abhiyan Viplav, Jan Huertas, Milos Galic
Publikováno v:
Journal of Cell Science
Clathrin-mediated endocytosis (CME) engages over 30 proteins to secure efficient cargo and membrane uptake. While the function of most core CME components is well established, auxiliary mechanisms crucial for fine-tuning and adaptation remain largely