Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jan Hudecek"'
Autor:
Maartje vanSeijen, Katarzyna Jóźwiak, Sarah E Pinder, Allison Hall, Savitri Krishnamurthy, Jeremy SJ Thomas, Laura C Collins, Jonathan Bijron, Joost Bart, Danielle Cohen, Wen Ng, Ihssane Bouybayoune, Hilary Stobart, Jan Hudecek, Michael Schaapveld, Alastair Thompson, Esther H Lips, Jelle Wesseling, The Grand Challenge PRECISION consortium.
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 3, Pp 233-242 (2021)
Abstract The prognostic value of cytonuclear grade in ductal carcinoma in situ (DCIS) is debated, partly due to high interobserver variability and the use of multiple guidelines. The aim of this study was to evaluate interobserver agreement in gradin
Externí odkaz:
https://doaj.org/article/018d235b3e01461b8b9e9bd581a263c5
Autor:
Iris Nederlof, Davide De Bortoli, Yacine Bareche, Bastien Nguyen, Michiel de Maaker, Gerrit K. J. Hooijer, Laurence Buisseret, Marleen Kok, Marcel Smid, Gert G. G. M. Van den Eynden, Arie B. Brinkman, Jan Hudecek, Jan Koster, Christos Sotiriou, Denis Larsimont, John W. M. Martens, Marc J. van de Vijver, Hugo M. Horlings, Roberto Salgado, Elia Biganzoli, Christine Desmedt
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-13 (2019)
Abstract Background Breast cancer (BC) immune infiltrates play a critical role in tumor progression and response to treatment. Besides stromal tumor infiltrating lymphocytes (sTILs) which have recently reached level 1B evidence as a prognostic marker
Externí odkaz:
https://doaj.org/article/df66d169093c486b9266d412cddea9ab
Autor:
Monika Brunclikova, Tomas Simurda, Jana Zolkova, Miroslava Sterankova, Ingrid Skornova, Miroslava Dobrotova, Zuzana Kolkova, Dusan Loderer, Marian Grendar, Jan Hudecek, Jan Stasko, Peter Kubisz
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 4, p 1083 (2022)
Congenital fibrinogen disorders are diseases associated with a bleeding tendency; however, there are also reports of thrombotic events. Fibrinogen plays a role in the pathogenesis of thrombosis due to altered plasma concentrations or modifications to
Externí odkaz:
https://doaj.org/article/bed0d4d8ea834cc18101bf03adc25b19
Autor:
Tomas Simurda, Rosanna Asselta, Jana Zolkova, Monika Brunclikova, Miroslava Dobrotova, Zuzana Kolkova, Dusan Loderer, Ingrid Skornova, Jan Hudecek, Zora Lasabova, Jan Stasko, Peter Kubisz
Publikováno v:
Diagnostics, Vol 11, Iss 11, p 2140 (2021)
Congenital fibrinogen disorders are rare pathologies of the hemostasis, comprising quantitative (afibrinogenemia, hypofibrinogenemia) and qualitative (dysfibrinogenemia and hypodysfibrinogenemia) disorders. The clinical phenotype is highly heterogene
Externí odkaz:
https://doaj.org/article/1b2962a9071f4dddb96c55543b50554b
Autor:
Ingrid Skornova, Tomas Simurda, Jan Stasko, Jana Zolkova, Juraj Sokol, Pavol Holly, Miroslava Dobrotova, Ivana Plamenova, Jan Hudecek, Monika Brunclikova, Alena Stryckova, Peter Kubisz
Publikováno v:
Diagnostics, Vol 11, Iss 11, p 2153 (2021)
von Willebrand disease (VWD) is reportedly the most common inherited bleeding disorder. This disorder develops as a result of defects and/or deficiency of the plasma protein von Willebrand factor (VWF). Laboratory testing for VWF-related disorders re
Externí odkaz:
https://doaj.org/article/044a479f87c64ae6989a805ed7e053f0
Autor:
Tomas Simurda, Monika Brunclikova, Rosanna Asselta, Sonia Caccia, Jana Zolkova, Zuzana Kolkova, Dusan Loderer, Ingrid Skornova, Jan Hudecek, Zora Lasabova, Jan Stasko, Peter Kubisz
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 13, p 4616 (2020)
Fibrinogen is a hexameric plasmatic glycoprotein composed of pairs of three chains (Aα, Bβ, and γ), which play an essential role in hemostasis. Conversion of fibrinogen to insoluble polymer fibrin gives structural stability, strength, and adhesive
Externí odkaz:
https://doaj.org/article/387723c270a74da99a2b53ab44313bbf
Autor:
Tomas Simurda, Jana Zolkova, Zuzana Snahnicanova, Dusan Loderer, Ingrid Skornova, Juraj Sokol, Jan Hudecek, Jan Stasko, Zora Lasabova, Peter Kubisz
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 1, p 100 (2017)
Congenital fibrinogen disorders are caused by mutations in one of the three fibrinogen genes that affect the synthesis, assembly, intracellular processing, stability or secretion of fibrinogen. Functional studies of mutant Bβ-chains revealed the imp
Externí odkaz:
https://doaj.org/article/d64fbd1de7f645bfa3cc78de7993812e
Autor:
David M. Hyman, Deborah Schrag, Alexia Iasonos, Philippe L. Bedard, Funda Meric-Bernstam, Mia Levy, Fabrice André, Charles L. Sawyers, Ben H. Park, Seth Sheffler-Collins, Jocelyn Lee, Stuart M. Gardos, Andrew Zarski, Nikolaus Schultz, JianJiong Gao, Shawn M. Sweeney, Ritika Kundra, Benjamin E. Gross, Jan Hudecek, Hugo Horlings, Chetna Wathoo, Christine M. Micheel, Semih Dogan, Natalie Blauvelt, Michele L. Lenoue-Newton, Michael J. Hasset, Monica Arnedos, Eva M. Lepisto, Celeste Yu, Bastien Nguyen, Qin Zhou, Lillian M. Smyth
Supplementary Tables and Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6befe845c9b36b4e38f5a11320c2bb0b
https://doi.org/10.1158/2159-8290.22535717
https://doi.org/10.1158/2159-8290.22535717
Autor:
David M. Hyman, Deborah Schrag, Alexia Iasonos, Philippe L. Bedard, Funda Meric-Bernstam, Mia Levy, Fabrice André, Charles L. Sawyers, Ben H. Park, Seth Sheffler-Collins, Jocelyn Lee, Stuart M. Gardos, Andrew Zarski, Nikolaus Schultz, JianJiong Gao, Shawn M. Sweeney, Ritika Kundra, Benjamin E. Gross, Jan Hudecek, Hugo Horlings, Chetna Wathoo, Christine M. Micheel, Semih Dogan, Natalie Blauvelt, Michele L. Lenoue-Newton, Michael J. Hasset, Monica Arnedos, Eva M. Lepisto, Celeste Yu, Bastien Nguyen, Qin Zhou, Lillian M. Smyth
AKT inhibitors have promising activity in AKT1E17K-mutant estrogen receptor (ER)–positive metastatic breast cancer, but the natural history of this rare genomic subtype remains unknown. Utilizing AACR Project GENIE, an international clinicogenomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0817109907ec64ff1ced72b981c80277
https://doi.org/10.1158/2159-8290.c.6547928.v1
https://doi.org/10.1158/2159-8290.c.6547928.v1
Autor:
Jonathan G. Bijron, Joost Bart, Danielle Cohen, Maartje van Seijen, Esther H. Lips, Katarzyna Jóźwiak, Allison Hall, Savitri Krishnamurthy, Jan Hudecek, Jelle Wesseling, Ihssane Bouybayoune, Laura C. Collins, Michael Schaapveld, Alastair M. Thompson, Jeremy Sj Thomas, Wen Ng, Sarah E Pinder, Hilary Stobart
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 3, Pp 233-242 (2021)
Journal of pathology clinical research. Wiley
The Journal of Pathology: Clinical Research
Journal of pathology clinical research. Wiley
The Journal of Pathology: Clinical Research
The prognostic value of cytonuclear grade in ductal carcinoma in situ (DCIS) is debated, partly due to high interobserver variability and the use of multiple guidelines. The aim of this study was to evaluate interobserver agreement in grading DCIS be