Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Jan Holgersson"'
Autor:
Lillian Streichart, Marie Felldin, Jana Ekberg, Lars Mjörnstedt, Per Lindnér, Annette Lennerling, Verena Bröcker, Johan Mölne, Jan Holgersson, Kristien Daenen, Lars Wennberg, Tomas Lorant, Seema Baid-Agrawal
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Chronic active antibody-mediated rejection (caAMR) in kidney transplants is associated with irreversible tissue damage and a leading cause of graft loss in the long-term. However, the treatment for caAMR remains a challenge to dat
Externí odkaz:
https://doaj.org/article/44ba75643e6d4314bde9aee06803a006
Autor:
Sven‐Erik Bartfay, Emanuele Bobbio, Sorosh Esmaily, Niklas Bergh, Jan Holgersson, Göran Dellgren, Entela Bollano, Kristjan Karason
Publikováno v:
ESC Heart Failure, Vol 10, Iss 4, Pp 2621-2629 (2023)
Abstract Aims Due to the shortage of heart donors, increasing numbers of heart transplantation (HTx) candidates are receiving long‐term mechanical circulatory support (MCS) as bridge‐to‐transplantation. Treatment with MCS is associated with inc
Externí odkaz:
https://doaj.org/article/64fa6ed2f05f479bb2c1255719c06756
Autor:
Bashar Shuoker, Michael J. Pichler, Chunsheng Jin, Hiroka Sakanaka, Haiyang Wu, Ana Martínez Gascueña, Jining Liu, Tine Sofie Nielsen, Jan Holgersson, Eva Nordberg Karlsson, Nathalie Juge, Sebastian Meier, Jens Preben Morth, Niclas G. Karlsson, Maher Abou Hachem
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
This study offers molecular insight into the sialidase and fucosidase decapping apparatus that initiates growth on mucin and promotes nutrient sharing by the dedicated mucolytic symbiont Akkermansia muciniphila with the mucus-associated microbiota.
Externí odkaz:
https://doaj.org/article/9a041ee102734a0eac2f4911f764b7f1
Publikováno v:
Stem Cell Research, Vol 29, Iss , Pp 24-27 (2018)
Successful hematopoietic stem and progenitor cell (HSPC) transplantation rests upon reliable methods for their enumeration in sources such as cord blood (CB). Methods used today are costly, time consuming and exhaust the limited number of cells neede
Externí odkaz:
https://doaj.org/article/de11cf79486d4b9c87a710dfc7e0dc3d
Autor:
Michael E. Breimer, Jan Holgersson
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
N-Glycolylneuraminic acid (Neu5Gc)-terminated glycans are present in all animal cells/tissues that are already used in the clinic such as bioprosthetic heart valves (BHV) as well as in those that potentially will be xenografted in the future to overc
Externí odkaz:
https://doaj.org/article/4d5b470237e44b4bb27d8548c8de531d
Publikováno v:
Biomolecules, Vol 5, Iss 3, Pp 1810-1831 (2015)
Sialylated glycans serve as key elements of receptors for many viruses, bacteria, and bacterial toxins. The microbial recognition and their binding specificity can be affected by the linkage of the terminal sugar residue, types of underlying sugar ch
Externí odkaz:
https://doaj.org/article/106ff8bb8622417da3ce1ae37854cc38
Autor:
Gustaf Ahlén, Lena Strindelius, Tomas Johansson, Anki Nilsson, Nathalie Chatzissavidou, Magnus Sjöblom, Ulrika Rova, Jan Holgersson
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46959 (2012)
Targeting antigens to antigen-presenting cells (APC) improve their immunogenicity and capacity to induce Th1 responses and cytotoxic T lymphocytes (CTL). We have generated a mucin-type immunoglobulin fusion protein (PSGL-1/mIgG(2b)), which upon expre
Externí odkaz:
https://doaj.org/article/fd913b472bff4453b075d65fb6cf27ba
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36378 (2012)
Helicobacter pylori colonizes the mucus niche of the gastric mucosa and is a risk factor for gastritis, ulcers and cancer. The main components of the mucus layer are heavily glycosylated mucins, to which H. pylori can adhere. Mucin glycosylation diff
Externí odkaz:
https://doaj.org/article/6a22a9baa31941c1870d51e2dbf6e095
Publikováno v:
Cell Transplantation, Vol 12 (2003)
Transplantation of allogeneic embryonic neural tissue is a potential treatment for patients with Parkinson's and Huntington's diseases. The supply of human donor tissue is limited, and alternatives such as the use of animal (e.g., porcine) donor tiss
Externí odkaz:
https://doaj.org/article/95df2b6b510d47b4afa1722832468730
Publikováno v:
Cell Transplantation, Vol 8 (1999)
Intracerebral transplantation of porcine embryonic dopamine-producing neurons has been suggested as a method to treat patients with Parkinson's disease. Even though the brain is an immunologically privileged site, neuronal xenografts are usually reje
Externí odkaz:
https://doaj.org/article/789c78880f104c26879c071fc1d25eff