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pro vyhledávání: '"Jan Hettwer"'
Autor:
Ulrike Meyer-Lindemann, Carina Mauersberger, Anna-Christina Schmidt, Aldo Moggio, Julia Hinterdobler, Xinghai Li, David Khangholi, Jan Hettwer, Christian Gräßer, Alexander Dutsch, Heribert Schunkert, Thorsten Kessler, Hendrik B. Sager
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundInflammation strongly contributes to atherosclerosis initiation and progression. Consequently, recent clinical trials pharmacologically targeted vascular inflammation to decrease the incidence of atherosclerosis-related complications. Colch
Externí odkaz:
https://doaj.org/article/28df352c26204badaafd3cad9c9270cf
Autor:
Nicholas H Adamstein, Wolfgang Koenig, Peter Libby, Christian Weber, Paul M. Ridker, Marcus-André Deutsch, Oliver Soehnlein, Carina Mauersberger, Hendrik B. Sager, Quinte Braster, Avril A. B. Robertson, Jan Hettwer, Benedikt Miritsch, Mark E. Cooper, Heribert Schunkert, Markus Krane, Xinghai Li, Aldo Moggio, Julia Hinterdobler, Hermann Gram, Olaf Groß, Thorsten Kessler
Publikováno v:
Cardiovascular Research, 118(13):337, 2778-2791. Oxford University Press
AIMS: Targeting vascular inflammation represents a novel therapeutic approach to reduce complications of atherosclerosis. Neutralizing the pro-inflammatory cytokine interleukin-1β (IL-1β) using canakinumab, a monoclonal antibody, reduces the incide