Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Jan Herman Kuiper"'
Publikováno v:
Surgeries, Vol 2, Iss 3, Pp 286-302 (2021)
A range of surgical techniques have been developed for the repair or regeneration of lesioned cartilage in the human knee and a corresponding array of scoring systems have been created to assess their outcomes. The published literature displays a wid
Externí odkaz:
https://doaj.org/article/8a8496a5cffc450c91573378b23b625e
Autor:
Jingsong Wang, Sally Roberts, Jan Herman Kuiper, Weiguo Zhang, John Garcia, Zhanfeng Cui, Karina Wright
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Meniscus degeneration is closely related to the progression of knee osteoarthritis (OA). However, there is currently a lack of quantitative and objective metrics to assess OA meniscal cell phenotypes. In this study we investigated the phenot
Externí odkaz:
https://doaj.org/article/4b449fd555fd4488a242218d7f8e8683
Publikováno v:
Children, Vol 9, Iss 5, p 728 (2022)
Objective: The North Star Ambulatory Assessment (NSAA) is a validated 17-item functional rating scale and widely used to assess motor function in boys with Duchenne muscular dystrophy (DMD). The SARS-CoV-2 pandemic and subsequent Government ‘lockdo
Externí odkaz:
https://doaj.org/article/558682724800455d895746837a50324e
Autor:
Sameera Abas, Jan Herman Kuiper, Sally Roberts, Helen McCarthy, Mike Williams, Andrew Bing, Bernhard Tins, Nilesh Makwana
Publikováno v:
Cells, Vol 11, Iss 4, p 629 (2022)
Osteochondral defects of the ankle (OCD) are being increasingly identified as a clinically significant consequence of injury to the ankle, with the potential to lead to osteoarthritis if left untreated. The aim of this retrospective cohort study was
Externí odkaz:
https://doaj.org/article/cf30e603a58641478ac26afe748ba8a0
Autor:
Timothy Hopkins, Karina T. Wright, Nicola J. Kuiper, Sally Roberts, Paul Jermin, Peter Gallacher, Jan Herman Kuiper
Publikováno v:
Cells, Vol 10, Iss 8, p 1903 (2021)
Chondrocyte-based cartilage repair strategies, such as articular chondrocyte implantation, are widely used, but few studies addressed the communication between native subchondral bone cells and the transplanted chondrocytes. An indirect co-culture mo
Externí odkaz:
https://doaj.org/article/993a17b4a68146efaa1178145b9be12c
Autor:
Michael R. Carmont, Jan Herman Kuiper, Karin Grävare Silbernagel, Jón Karlsson, Katarina Nilsson-Helander
Publikováno v:
Journal of Experimental Orthopaedics, Vol 4, Iss 1, Pp 1-10 (2017)
Abstract Background Rupture of the Achilles tendon often leads to long-term morbidity, particularly calf weakness associated with tendon elongation. Operative repair of Achilles tendon ruptures leads to reduced tendon elongation. Tendon lengthening i
Externí odkaz:
https://doaj.org/article/d773c1063e944bd7ad485cc96b01dea9
Publikováno v:
Journal of Tissue Engineering, Vol 10 (2019)
Autologous chondrocyte implantation is a cell-based therapy for treating chondral defects. The procedure begins by inserting chondrocytes into the defect region. The chondrocytes initiate healing by proliferating and depositing extracellular matrix,
Externí odkaz:
https://doaj.org/article/573dc42f4a8a4edca8a4ef985a96ab24
Publikováno v:
Journal of Tissue Engineering, Vol 10 (2019)
We present a mathematical model of cartilage regeneration after cell therapy, to show how co-implantation of stem cells (mesenchymal stem cells) and chondrocytes into a cartilage defect can impact chondral healing. The key mechanisms involved in the
Externí odkaz:
https://doaj.org/article/5be7ee3ea9aa457581821b21c312fae9
Publikováno v:
Biomolecules, Vol 11, Iss 1, p 92 (2021)
Articular cartilage is considered to have limited regenerative capacity, which has led to the search for therapies to limit or halt the progression of its destruction. Perlecan, a multifunctional heparan sulphate (HS) proteoglycan, promotes embryonic
Externí odkaz:
https://doaj.org/article/d26fffac2e8d4b8d839354fc3d37b42a
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47169 (2012)
Primary cell transplantation is currently the gold standard for cell replacement in Parkinson's disease. However, the number of donors needed to treat a single patient is high, and the functional outcome is sometimes variable. The present work explor
Externí odkaz:
https://doaj.org/article/a24f3a98fbdb4d24a68178742d547c69