Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Jan Harry Cabungcal"'
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract A large body of evidence suggests that intrauterine growth restriction (IUGR) impedes normal neurodevelopment and predisposes the offspring to cognitive and behavioral deficits later in life. A significantly higher risk rate for schizophreni
Externí odkaz:
https://doaj.org/article/3b554ee241eb4b0fbe64e49c1168b814
Publikováno v:
Neurobiology of Disease, Vol 109, Iss , Pp 64-75 (2018)
The GluN2A subunit of NMDA receptors (NMDARs) plays a critical role during postnatal brain development as its expression increases while Glun2B expression decreases. Mutations and polymorphisms in GRIN2A gene, coding for GluN2A, are linked to develop
Externí odkaz:
https://doaj.org/article/3540164d33cf40e88317a981da1dd451
Autor:
Yohan van de Looij, Camille Larpin, Jan-Harry Cabungcal, Eduardo F. Sanches, Audrey Toulotte, Kim Q. Do, Stéphane V. Sizonenko
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Introduction: Intrauterine Growth Restriction (IUGR) refers to an impaired development of the fetus and hence results in adverse neurodevelopmental and psychiatric consequences later in life. Lactoferrin (Lf) is a glycoprotein present in milk that ha
Externí odkaz:
https://doaj.org/article/827954e2f52141c68ef9f467b3d5761d
Autor:
Corinne El Khoueiry, Jan-Harry Cabungcal, Zita Rovó, Margot Fournier, Kim Q. Do, Pascal Steullet
Publikováno v:
Molecular psychiatry, vol. 27, no. 4, pp. 2042-2051
Impairment of parvalbumin interneurons induced by oxidative stress (OxS) is a “hub” on which converge several genetic and environmental risk factors associated with schizophrenia. In patients, this could be a mechanism leading to anomalies of the
Autor:
Daniella Dwir, Philippe Conus, Enea Parietti, Raoul Jenni, Jan-Harry Cabungcal, Paul Klauser, Michel Cuenod, Kim Q. Do, Lijing Xin, Martine Cleusix, Pascal Steullet, Basilio Giangreco
Publikováno v:
Schizophrenia Bulletin
Schizophrenia bulletin, vol. 47, no. 6, pp. 1782-1794
Schizophrenia bulletin, vol. 47, no. 6, pp. 1782-1794
Research in schizophrenia (SZ) emphasizes the need for new therapeutic approaches based on antioxidant/anti-inflammatory compounds and psycho-social therapy. A hallmark of SZ is a dysfunction of parvalbumin-expressing fast-spiking interneurons (PVI),
Autor:
Elidie Béard, Michel Cuenod, Micah M. Murray, Kim Q. Do, Ines Khadimallah, Chrysa Retsa, Jan-Harry Cabungcal, Jean-François Knebel, Kevin M. Spencer, Raoul Jenni, Martine Cleusix, Milena Siciliano, Paul Klauser, Philippe Conus, Pascal Steullet, Margot Fournier
Publikováno v:
Molecular psychiatry, vol. 27, no. 2, pp. 1192-1204
Early detection and intervention in schizophrenia requires mechanism-based biomarkers that capture neural circuitry dysfunction, allowing better patient stratification, monitoring of disease progression and treatment. In prefrontal cortex and blood o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be327964eb92d69e0d56715759d66a98
https://serval.unil.ch/resource/serval:BIB_14C65851BA9E.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_14C65851BA9E.P001/REF.pdf
Publikováno v:
Molecular psychiatry, vol. 26, no. 12, pp. 7679-7689
Recent evidence showed thalamic abnormalities in schizophrenia involving disruptions to the parvalbumin neurons in the thalamic reticular nucleus (TRN). However, their functional consequences, as well as a potential linkage to oxidative stress, are u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3405c9c9ad73b244103d3df062aee1
https://serval.unil.ch/notice/serval:BIB_1E57D5A8721C
https://serval.unil.ch/notice/serval:BIB_1E57D5A8721C
Autor:
Corinne, El Khoueiry, Jan-Harry, Cabungcal, Zita, Rovó, Margot, Fournier, Kim Q, Do, Pascal, Steullet
Publikováno v:
Molecular psychiatry. 27(4)
Impairment of parvalbumin interneurons induced by oxidative stress (OxS) is a "hub" on which converge several genetic and environmental risk factors associated with schizophrenia. In patients, this could be a mechanism leading to anomalies of the tha
Autor:
Jan-Harry Cabungcal, Michel Cuenod, Pascal Steullet, Ines Khadimallah, Kim Q. Do, Philippe Conus, Daniella Dwir, Paul Klauser
Publikováno v:
Molecular psychiatry. 27(4)
A growing body of evidence has emerged demonstrating a pathological link between oxidative stress and schizophrenia. This evidence identifies oxidative stress as a convergence point or “central hub” for schizophrenia genetic and environmental ris
Autor:
Jan-Harry Cabungcal, Delphine Preissmann, Caroline Delseth, Michel Cuénod, Kim Q. Do, Françoise Schenk
Publikováno v:
Neurobiology of Disease, Vol 26, Iss 3, Pp 634-645 (2007)
Glutathione (GSH) metabolism dysfunction is one risk factor in schizophrenia. A transitory brain GSH deficit was induced in Wistar (WIS) and mutant (ODS; lacking ascorbic acid synthesis) rats using BSO (l-buthionine-(S,R)-sulfoximine) from post-natal
Externí odkaz:
https://doaj.org/article/d97b03f054d74e2b9d1b8584bd9927bc