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Akademický článek

Autor: Arve Vorland Pedersen, Jan Harry Størksen, Trine Tegdan Moholdt

Publikováno v: Fysioterapeuten, Vol 72, Iss 11, Pp 18-22 (2005)

Much attention has in the recent years been given to the concept of neuromuscular training (NMT), and it has been argued that such training should replace traditional regimes in the rehabilitation of athletes with ruptures of the anterior cruciate li

Externí odkaz: https://doaj.org/article/fb3041019cb54bcc8d6f9fab6e26626a

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Akademický článek

Low protein-induced intrauterine growth restriction as a risk factor for schizophrenia phenotype in a rat model: assessing the role of oxidative stress and neuroinflammation interaction

Autor: Larissa Allgäuer, Jan-Harry Cabungcal, Catherine Yzydorczyk, Kim Quang Do, Daniella Dwir

Publikováno v: Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)

Abstract A large body of evidence suggests that intrauterine growth restriction (IUGR) impedes normal neurodevelopment and predisposes the offspring to cognitive and behavioral deficits later in life. A significantly higher risk rate for schizophreni

Externí odkaz: https://doaj.org/article/3b554ee241eb4b0fbe64e49c1168b814

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Akademický článek

A developmental redox dysregulation leads to spatio-temporal deficit of parvalbumin neuron circuitry in a schizophrenia mouse model

Autor: Cabungcal, Jan-Harry, Steullet, Pascal, Kraftsik, Rudolf, Cuenod, Michel, Do, Kim Q.

Publikováno v: In Schizophrenia Research November 2019 213:96-106

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Akademický článek

A lack of GluN2A-containing NMDA receptors confers a vulnerability to redox dysregulation: Consequences on parvalbumin interneurons, and their perineuronal nets

Autor: Romain Cardis, Jan-Harry Cabungcal, Daniella Dwir, Kim Q. Do, Pascal Steullet

Publikováno v: Neurobiology of Disease, Vol 109, Iss , Pp 64-75 (2018)

The GluN2A subunit of NMDA receptors (NMDARs) plays a critical role during postnatal brain development as its expression increases while Glun2B expression decreases. Mutations and polymorphisms in GRIN2A gene, coding for GluN2A, are linked to develop

Externí odkaz: https://doaj.org/article/3540164d33cf40e88317a981da1dd451

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Akademický článek

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Developmental oxidative stress leads to T-type Ca2+ channel hypofunction in thalamic reticular nucleus of mouse models pertinent to schizophrenia

Autor: Corinne El Khoueiry, Jan-Harry Cabungcal, Zita Rovó, Margot Fournier, Kim Q. Do, Pascal Steullet

Publikováno v: Molecular psychiatry, vol. 27, no. 4, pp. 2042-2051

Impairment of parvalbumin interneurons induced by oxidative stress (OxS) is a “hub” on which converge several genetic and environmental risk factors associated with schizophrenia. In patients, this could be a mechanism leading to anomalies of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29191fafe57b3339cf92a232d16ffa9
https://doi.org/10.1038/s41380-021-01425-2

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Timely N-Acetyl-Cysteine and Environmental Enrichment Rescue Oxidative Stress-Induced Parvalbumin Interneuron Impairments via MMP9/RAGE Pathway: A Translational Approach for Early Intervention in Psychosis

Autor: Daniella Dwir, Philippe Conus, Enea Parietti, Raoul Jenni, Jan-Harry Cabungcal, Paul Klauser, Michel Cuenod, Kim Q. Do, Lijing Xin, Martine Cleusix, Pascal Steullet, Basilio Giangreco

Publikováno v: Schizophrenia Bulletin
Schizophrenia bulletin, vol. 47, no. 6, pp. 1782-1794

Research in schizophrenia (SZ) emphasizes the need for new therapeutic approaches based on antioxidant/anti-inflammatory compounds and psycho-social therapy. A hallmark of SZ is a dysfunction of parvalbumin-expressing fast-spiking interneurons (PVI),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f30a4c6d6c3d75b3a4df33616f2180
http://europepmc.org/articles/PMC8530393

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